In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis

Optimal dosing regimen of biapenem in Chinese patients with lower respiratory tract infections based on population pharmacokinetic/pharmacodynamic modelling and Monte Carlo simulation

(2016) Jing Dong et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Carbapenems against Mycobacterium tuberculosis: a review of the evidence

(2016) D. Jaganath et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Pharmacokinetics and brain penetration of carbapenems in mice

(2016) Kazuaki Matsumoto et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Non-classical transpeptidases yield insight into new antibacterials

(2016) Pankaj Kumar et al.   Nature Chemical Biology

β-Lactams against Tuberculosis — New Trick for an Old Dog?

(2016) Andreas H. Diacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Repurposing clinically approved cephalosporins for tuberculosis therapy

(2016) Santiago Ramón-García et al.   Scientific Reports

In VitroActivity of β-Lactams in Combination with β-Lactamase Inhibitors against Multidrug-Resistant Mycobacterium tuberculosis Isolates

(2015) Dan Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenems and Rifampin Exhibit Synergy against Mycobacterium tuberculosis and Mycobacterium abscessus

(2015) Amit Kaushik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting DnaN for tuberculosis therapy using novel griselimycins

(2015) A. Kling et al.   SCIENCE

In VitroSusceptibility of Mycobacterium tuberculosis Isolates to an Oral Carbapenem Alone or in Combination with β-Lactamase Inhibitors

(2014) Yasuhiro Horita et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rapid Cytolysis of Mycobacterium tuberculosis by Faropenem, an Orally Bioavailable β-Lactam Antibiotic

(2014) Neeraj Dhar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nonclassical Transpeptidases of Mycobacterium tuberculosis Alter Cell Size, Morphology, the Cytosolic Matrix, Protein Localization, Virulence, and Resistance to  -Lactams

(2014) M. K. Schoonmaker et al.   JOURNAL OF BACTERIOLOGY

In VitroCross-Linking of Mycobacterium tuberculosis Peptidoglycan by l,d-Transpeptidases and Inactivation of These Enzymes by Carbapenems

(2013) Mathilde Cordillot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroandIn VivoEfficacy of β-Lactams against Replicating and Slowly Growing/Nonreplicating Mycobacterium tuberculosis

(2013) Suresh Solapure et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis

(2012) Ian M. Rosenthal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Meropenem inhibits D,D-carboxypeptidase activity inMycobacterium tuberculosis

(2012) Pradeep Kumar et al.   MOLECULAR MICROBIOLOGY

Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2

(2012) Sabri B. Erdemli et al.   STRUCTURE

Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis

(2011) Rokeya Tasneen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenems: Past, Present, and Future

(2011) Krisztina M. Papp-Wallace et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin

(2010) Radhika Gupta et al.   NATURE MEDICINE

Comparison of the Pharmacodynamics of Biapenem in Bronchial Epithelial Lining Fluid in Healthy Volunteers Given Half-Hour and Three-Hour Intravenous Infusions

(2009) E. Kikuchi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis

(2009) J.-E. Hugonnet et al.   SCIENCE

Pharmacokinetic-Pharmacodynamic Target Attainment Analysis of Biapenem in Adult Patients: A Dosing Strategy

(2008) Kazuro Ikawa et al.   CHEMOTHERAPY

Parenteral carbapenems

(2008) P.M. Shah   CLINICAL MICROBIOLOGY AND INFECTION

The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by L,D-Transpeptidation

(2008) M. Lavollay et al.   JOURNAL OF BACTERIOLOGY