Pharmacodynamics of dose-escalated ‘front-loading’ polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli

Paradoxical Effect of Polymyxin B: High Drug Exposure Amplifies Resistance in Acinetobacter baumannii

(2016) Brian T. Tsuji et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Detection ofmcr-1among Escherichia coli Clinical Isolates Collected Worldwide as Part of the SENTRY Antimicrobial Surveillance Program in 2014 and 2015

(2016) Mariana Castanheira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of the Plasmid-Mediatedmcr-1Gene in Colistin-Resistant Enterobacter aerogenes and Enterobacter cloacae: TABLE 1

(2016) Kun-jiao Zeng et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Escherichia coli Harboringmcr-1andblaCTX-Mon a Novel IncF Plasmid: First Report ofmcr-1in the United States

(2016) Patrick McGann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies to Control Antimicrobial Resistance From Food Animal Production

(2016) Peter C. Collignon et al.   CLINICAL INFECTIOUS DISEASES

Molecular mechanisms of polymyxin resistance: knowns and unknowns

(2016) Sophie Baron et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Detection of the plasmid-mediatedmcr-1gene conferring colistin resistance in human and food isolates ofSalmonella entericaandEscherichia coliin England and Wales

(2016) Michel Doumith et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High-intensity meropenem combinations with polymyxin B: new strategies to overcome carbapenem resistance inAcinetobacter baumannii

(2016) Justin R. Lenhard et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Plasmid-mediated carbapenem and colistin resistance in a clinical isolate of Escherichia coli

(2016) Laurent Poirel et al.   LANCET INFECTIOUS DISEASES

Dissemination of the mcr-1 colistin resistance gene

(2016) Michael R Mulvey et al.   LANCET INFECTIOUS DISEASES

Colistin resistance gene mcr-1 in extended-spectrum β-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany

(2016) Linda Falgenhauer et al.   LANCET INFECTIOUS DISEASES

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

Antibiotic Adjuvants: Rescuing Antibiotics from Resistance

(2016) Gerard D. Wright   TRENDS IN MICROBIOLOGY

Colistin- and Carbapenem-Resistant Escherichia coli Harboring mcr-1 and bla NDM-5 , Causing a Complicated Urinary Tract Infection in a Patient from the United States: TABLE 1 

(2016) José R. Mediavilla et al.   mBio

Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens

(2016) Soon-Ee Cheah et al.   Scientific Reports

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

(2016) Mohd Hafidz Mahamad Maifiah et al.   Scientific Reports

Development and validation of a liquid chromatography–mass spectrometry assay for polymyxin B in bacterial growth media

(2014) Soon-Ee Cheah et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

New Dosing Strategies for an Old Antibiotic: Pharmacodynamics of Front-Loaded Regimens of Colistin at Simulated Pharmacokinetics in Patients with Kidney or Liver Disease

(2013) Gauri G. Rao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens

(2013) Ana M. Sandri et al.   CLINICAL INFECTIOUS DISEASES

Development of a New Pre- and Post-Processing Tool (SADAPT-TRAN) for Nonlinear Mixed-Effects Modeling in S-ADAPT

(2011) Jurgen Bernd Bulitta et al.   AAPS Journal

Attenuation of Colistin Bactericidal Activity by High Inoculum of Pseudomonas aeruginosa Characterized by a New Mechanism-Based Population Pharmacodynamic Model

(2010) J. B. Bulitta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY