PET Tau and Amyloid-β Burden in Mild Alzheimer’s Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers

Regional profiles of the candidate tau PET ligand18F-AV-1451 recapitulate key features of Braak histopathological stages

(2016) Adam J. Schwarz et al.   BRAIN

Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease

(2016) Rik Ossenkoppele et al.   BRAIN

The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging

(2016) Brian A. Gordon et al.   BRAIN

Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly

(2016) Jasmeer P. Chhatwal et al.   NEUROLOGY

PET Imaging of Tau Deposition in the Aging Human Brain

(2016) Michael Schöll et al.   NEURON

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

[18F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation

(2016) W. Richard Bevan Jones et al.   Annals of Clinical and Translational Neurology

Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue

(2015) Marta Marquié et al.   ANNALS OF NEUROLOGY

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Alzheimer’s disease cerebrospinal fluid biomarker in cognitively normal subjects

(2015) Jon B. Toledo et al.   BRAIN

Regional β-amyloid burden does not correlate with cognitive or language deficits in Alzheimer's disease presenting as aphasia

(2015) Y. Jung et al.   EUROPEAN JOURNAL OF NEUROLOGY

Tau imaging: early progress and future directions

(2015) Victor L Villemagne et al.   LANCET NEUROLOGY

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Fluid Biomarkers in Clinical Trials of Alzheimer’s Disease Therapeutics

(2015) Aaron Ritter et al.   Frontiers in Neurology

PET Imaging of Tau Pathology in Alzheimer’s Disease and Tauopathies

(2015) Olga G. James et al.   Frontiers in Neurology

Medial temporal atrophy in early and late-onset Alzheimer's disease

(2014) Enrica Cavedo et al.   NEUROBIOLOGY OF AGING

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accuracy of Brain Amyloid Detection in Clinical Practice Using Cerebrospinal Fluid β-Amyloid 42

(2014) Sebastian Palmqvist et al.   JAMA Neurology

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI

(2013) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

[18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

(2013) Chun-Fang Xia et al.   Alzheimers & Dementia

Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer’s disease

(2013) Manja Lehmann et al.   BRAIN

Different patterns of gray matter atrophy in early- and late-onset Alzheimer’s disease

(2013) Christiane Möller et al.   NEUROBIOLOGY OF AGING

Brain  -amyloid load approaches a plateau

(2013) C. R. Jack et al.   NEUROLOGY

FDG PET and MRI in Logopenic Primary Progressive Aphasia versus Dementia of the Alzheimer’s Type

(2013) Ajay Madhavan et al.   PLoS One

Amyloid imaging in dementias with atypical presentation

(2012) David A. Wolk et al.   Alzheimers & Dementia

Nonamnestic Presentations of Early-Onset Alzheimer’s Disease

(2012) Mario F. Mendez et al.   American Journal of Alzheimers Disease and Other Dementias

Early-onset Alzheimer disease clinical variants: Multivariate analyses of cortical thickness

(2012) G. R. Ridgway et al.   NEUROLOGY

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study

(2011) Melissa E Murray et al.   LANCET NEUROLOGY

Amyloid PET imaging in patients with mild cognitive impairment: A 2-year follow-up study

(2011) J. Koivunen et al.   NEUROLOGY

Increased metabolic vulnerability in early-onset Alzheimer’s disease is not related to amyloid burden

(2010) Gil D. Rabinovici et al.   BRAIN

Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease

(2010) C. R. Jack et al.   BRAIN

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy

(2010) Andri C. Tziortzi et al.   NEUROIMAGE

Cerebrospinal fluid tau and ptau181increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease

(2009) Anne M. Fagan et al.   EMBO Molecular Medicine

Conversion of amyloid positive and negative MCI to AD over 3 years: An 11C-PIB PET study

(2009) A. Okello et al.   NEUROLOGY

Most rapid cognitive decline in APOE ε4 negative Alzheimer's disease with early onset

(2009) A. E. van der Vlies et al.   PSYCHOLOGICAL MEDICINE