Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

(2016) Yaming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

(2016) Amanda Heslegrave et al.   Molecular Neurodegeneration

Reduced functional segregation between the default mode network and the executive control network in healthy older adults: A longitudinal study

(2016) Kwun Kei Ng et al.   NEUROIMAGE

TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

(2016) Naiara Celarain et al.   Clinical Epigenetics

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

TREM2 mRNA Expression in Leukocytes Is Increased in Alzheimer’s Disease and Schizophrenia

(2015) Yoko Mori et al.   PLoS One

Relationship between the Montreal Cognitive Assessment and Mini-mental State Examination for assessment of mild cognitive impairment in older adults

(2015) Paula T. Trzepacz et al.   BMC Geriatrics

Blood-Based Proteomic Biomarkers of Alzheimer’s Disease Pathology

(2015) Alison L. Baird et al.   Frontiers in Neurology

TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices

(2014) Lih-Fen Lue et al.   BRAIN PATHOLOGY

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(2012) Gaelle Naert et al.   MOLECULAR MEDICINE

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

(2012) N. H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

CC Chemokine Receptor 2 Deficiency Aggravates Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) G. Naert et al.   JOURNAL OF NEUROSCIENCE

APOE4 is associated with greater atrophy of the hippocampal formation in Alzheimer's disease

(2011) Michela Pievani et al.   NEUROIMAGE

Wechsler Adult Intelligence Scale IV (WAIS IV): Return of the Gold Standard

(2009) David E. Hartman   APPLIED NEUROPSYCHOLOGY

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

(2009) Christine L. Hsieh et al.   JOURNAL OF NEUROCHEMISTRY

Apolipoprotein E ε4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia

(2009) Federica Agosta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice

(2008) Stefanie Frank et al.   GLIA

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA