Rare Genetic Variant in SORL1 May Increase Penetrance of Alzheimer’s Disease in a Family with Several Generations of APOE-ɛ4 Homozygosity

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease

(2016) Jan Verheijen et al.   ACTA NEUROPATHOLOGICA

Coding mutations inSORL1and Alzheimer disease

(2015) Badri N. Vardarajan et al.   ANNALS OF NEUROLOGY

ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA

(2015) Ryuji Yajima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease

(2015) G Nicolas et al.   MOLECULAR PSYCHIATRY

2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease

(2014) Keith N. Fargo et al.   Alzheimers & Dementia

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease

(2014) Frank Jessen et al.   Alzheimers & Dementia

Imputation of truncated p-values for meta-analysis methods and its genomic application

(2014) Shaowu Tang et al.   Annals of Applied Statistics

Apolipoprotein E in Alzheimer's Disease: An Update

(2014) Jin-Tai Yu et al.   Annual Review of Neuroscience

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Lysosomal Sorting of Amyloid-  by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation

(2014) S. Caglayan et al.   Science Translational Medicine

Disease variants in genomes of 44 centenarians

(2014) Yun Freudenberg-Hua et al.   Molecular Genetics & Genomic Medicine

Dyslipidemia and the Risk of Alzheimer’s Disease

(2013) Christiane Reitz   Current Atherosclerosis Reports

Transmembrane Protein 214 (TMEM214) Mediates Endoplasmic Reticulum Stress-induced Caspase 4 Enzyme Activation and Apoptosis

(2013) Chao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sorting receptor SORLA - a trafficking path to avoid Alzheimer disease

(2013) T. E. Willnow et al.   JOURNAL OF CELL SCIENCE

Genetics of cerebral amyloid angiopathy: systematic review and meta-analysis

(2013) K. Rannikmae et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Caspase-4 Is Required for Activation of Inflammasomes

(2012) G. Sollberger et al.   JOURNAL OF IMMUNOLOGY

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

(2011) E Genin et al.   MOLECULAR PSYCHIATRY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population

(2010) M. Schuur et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

EEG abnormalities in early and late onset Alzheimer's disease: understanding heterogeneity

(2010) H. de Waal et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE ɛ4 allele

(2010) Wiesje M van der Flier et al.   LANCET NEUROLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4

(2009) Yuji Kajiwara et al.   PLoS One

EEG alterations in non-demented individuals related to apolipoprotein E genotype and to risk of Alzheimer disease

(2007) N.V. Ponomareva et al.   NEUROBIOLOGY OF AGING