Review
Neurosciences
Janusz K. Rybakowski
Summary: The narrative review focuses on mood stabilizers. It provides the author's definition of mood-stabilizing drugs and describes the two generations of drugs that meet this definition. The article presents the clinical experiences with first and second-generation mood stabilizers and discusses their use in preventing recurrences of bipolar mood disorder.
Article
Psychology, Clinical
Chelsea Wood-Ross, Michael W. Best, Melissa Milanovic, Christopher R. Bowie
Summary: Individuals with depression tend to avoid cognitive challenges by opting to decrease task difficulty and showing increased EEG alpha power on high challenge levels, indicating disengagement from the task. This behavior has implications for understanding cognitive performance and modifying cognitive impairment in depression.
COGNITIVE THERAPY AND RESEARCH
(2021)
Article
Clinical Neurology
Muriel Vicent-Gil, Sara Gonzalez-Simarro, Beatriz Raventos, Javier Vera, Eduardo D. Marin Martinez, Carlota Sabate-Cao, Josefina Perez-Blanco, Dolors Puigdemont, Javier de Diego-Adelino, Carlo Alemany, Maria Serra-Blasco, Narcis Cardoner, Maria J. Portella
Summary: This study aimed to investigate the impact of INCREM on psychosocial functioning and cognitive performance in clinically remitted depressed patients. The results showed significant improvements in psychosocial functioning and cognitive performance in the INCREM group, which were maintained six months later.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Behavioral Sciences
Aleksandra Lalovic, Shijing Wang, John G. Keilp, Christopher R. Bowie, Sidney H. Kennedy, Sakina J. Rizvi
Summary: Cognitive deficits may serve as neurocognitive markers for identifying individuals at risk for suicide, particularly in depressed suicide attempters. Further studies are needed to clarify the role of cognitive deficits in specific subtypes of individuals at risk for suicide, and to explore the potential of cognitive remediation and psychological interventions.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Biochemistry & Molecular Biology
Lorenza Lucidi, Mauro Pettorruso, Federica Vellante, Francesco Di Carlo, Franca Ceci, Maria Chiara Santovito, Ilenia Di Muzio, Michele Fornaro, Antonio Ventriglio, Carmine Tomasetti, Alessandro Valchera, Alessandro Gentile, Yong-Ku Kim, Giovanni Martinotti, Silvia Fraticelli, Massimo Di Giannantonio, Domenico De Berardis
Summary: The gut microbiota plays a crucial role in maintaining homeostasis, growth, and digestive processes. It also influences the intercommunication system between the gut and the brain, potentially impacting the pathogenesis and clinical management of Bipolar Disorder. Current literature suggests a relationship between compositional alterations in the gut microbiota and BD, with potential benefits in treating BD symptoms through modifications in the microbiota composition. Further research is needed to explore the potential of correcting gut microbiota alterations as a novel strategy in BD management.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Psychiatry
Alice M. Saperstein, C. Jean Choi, Carol Jahshan, David A. Lynch, Melanie Wall, Michael F. Green, Alice Medalia
Summary: The research indicates that different sites have a significant impact on the cognitive training outcomes of schizophrenia patients, with better results in the NY site. Treatment characteristics have a greater influence on cognitive improvement, while participant characteristics are more important for changes in functional capacity.
SCHIZOPHRENIA RESEARCH
(2021)
Article
Psychology, Clinical
Julie Ramain, Lilith Abrahamyan Empson, Luis Alameda, Alessandra Solida, Julien Elowe, Nadir Mebdouhi, Philippe Conus, Philippe Golay
Summary: This study aims to investigate the impact of mood disturbances on the course and outcome of early psychosis. The results revealed that patients with co-occurring manic and depressive dimensions had poorer outcomes, highlighting the importance of accurate assessment and treatment of mood dimensions in early psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Multidisciplinary
Sunniva Brurok Myklebost, Tine Nordgreen, Oda Stakkestad Klakegg, Asa Hammar
Summary: This study examined the long-term effects of an internet-delivered intervention on residual cognitive deficits, rumination, and symptoms of major depressive disorder (MDD). The results showed a reduction in cognitive deficits and rumination, but an increase in symptoms of MDD. Additionally, participants who experienced a new episode of MDD showed different outcomes compared to those who did not.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Catarina Rodrigues Cordeiro, Beatriz Romao Corte-Real, Rodrigo Saraiva, Benicio N. Frey, Flavio Kapczinski, Taiane de Azevedo Cardoso
Summary: This systematic review aimed to identify triggers of acute mood episodes in bipolar disorder (BD). The review found that pharmacotherapy, particularly the use of antidepressants, was the trigger with the strongest evidence for manic/hypomanic relapse. Other identified triggers for mania included brain stimulation, energy drinks, acetyl-lcarnitine, St. John's wort, seasonal changes, hormonal changes, and viral infections. However, there is a lack of evidence regarding triggers for depressive relapses in BD, highlighting the need for further research in this area.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Psychiatry
Darryl Bassett, Philip Boyce, Bill Lyndon, Roger Mulder, Gordon Parker, Richard Porter, Ajeet Singh, Erica Bell, Amber Hamilton, Grace Morris, Gin S. Malhi
Summary: Psychotic episodes occur in a significant proportion of patients with major mood disorders, and their nature and management are less understood compared to non-psychotic periods of illness. This is concerning due to the higher risk of suicide and comorbidity in this subtype of mood disorder. The relationship between psychotic mood and other forms of psychosis, particularly schizophrenia, remains poorly understood. Therefore, our targeted review aims to provide clinical context and a framework for managing these disorders in real-world practice, considering both biological and psychological interventions.
SCHIZOPHRENIA RESEARCH
(2022)
Review
Behavioral Sciences
Susana Gomes-da-Costa, Wolfgang Marx, Filippo Corponi, Gerard Anmella, Andrea Murru, Maria Teresa Pons-Cabrera, Anna Gimenez-Palomo, Felipe Gutierrez-Arango, Cristian Daniel Llach, Giovanna Fico, Georgios D. Kotzalidis, Norma Verdolini, Marc Valenti, Michael Berk, Eduard Vieta, Isabella Pacchiarotti
Summary: This study found through a systematic review and meta-analysis that the use of lithium in patients with Bipolar Disorder does not significantly lead to weight gain. Shorter treatment duration is associated with more pronounced weight gain. There were no significant differences in weight gain between lithium and placebo, but weight gain with lithium was lower compared to other active comparators.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Clinical Neurology
Alexandra Therond, Patrizia Pezzoli, Maria Abbas, Andrea Howard, Christopher R. Bowie, Synthia Guimond
Summary: The study suggests that CR has a positive impact on improving global cognition, verbal memory, attention/processing speed, working memory, and executive functioning in adults with major depressive disorder, with no significant effects on visuospatial memory and verbal fluency. Additionally, no significant moderating effects were observed in terms of participant age, session duration, or session format.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Psychology, Multidisciplinary
Yannick Vander Zwalmen, Kristof Hoorelbeke, Eveline Liebaert, Constance Neve de Mevergnies, Ernst H. W. Koster
Summary: It is increasingly recognized that cognitive impairment has an important role in depression vulnerability. Cognitive remediation strategies and cognitive control training (CCT) have gained attention as possible interventions for depression. Recent studies suggest a small to medium effect on depression vulnerability indicators. Despite initial evidence for the efficacy and effectiveness of CCT, there are still several central questions to be addressed, including potential working mechanisms, optimal administration conditions, and the interaction between CCT and existing depression treatments.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Clinical Neurology
Jennifer C. P. Gillies, David J. A. Dozois
Summary: This study aimed to evaluate the duration of sad mood induced by commonly used Mood Induction Procedures (MIP) and found that the effects were not sufficiently persistent, except for memory-related MIPs which induced the most persistent sad mood.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Clinical
Sunniva Brurok Myklebost, Ole Myklebust Amundsen, Adam W. A. Geraghty, Yavuz Inal, Asa Hammar, Tine Nordgreen
Summary: This study aimed to understand the needs and perspectives of adults with a history of depression during the development of a novel internet-based intervention for residual cognitive symptoms after major depressive disorder (MDD). The findings from exploratory and think-aloud interviews highlighted the experiences of cognitive difficulties, coping strategies, and the requirements for an intervention. The results suggest that including psychoeducation, compensatory strategies, and elements to enhance acceptance and motivation in the intervention may address the concerns and consequences of cognitive difficulties.
JOURNAL OF MENTAL HEALTH
(2022)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)