Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide

(2017) Sarath Vijayakumar et al.   HUMAN MOLECULAR GENETICS

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

(2016) Richard S Finkel et al.   LANCET

Splice-switching antisense oligonucleotides as therapeutic drugs

(2016) Mallory A. Havens et al.   NUCLEIC ACIDS RESEARCH

Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities

(2015) Pranav Mathur et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Novel therapeutics in hypertriglyceridemia

(2015) Steven E. Gryn et al.   CURRENT OPINION IN LIPIDOLOGY

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

(2014) John A Zuris et al.   NATURE BIOTECHNOLOGY

Evolution and development of the tetrapod auditory system: an organ of Corti-centric perspective

(2013) Bernd Fritzsch et al.   EVOLUTION & DEVELOPMENT

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness

(2013) Jennifer J Lentz et al.   NATURE MEDICINE

Eya1-Six1 Interaction Is Sufficient to Induce Hair Cell Fate in the Cochlea by Activating Atoh1 Expression in Cooperation with Sox2

(2012) Mohi Ahmed et al.   DEVELOPMENTAL CELL

Over Half the Hair Cells in the Mouse Utricle First Appear After Birth, with Significant Numbers Originating from Early Postnatal Mitotic Production in Peripheral and Striolar Growth Zones

(2012) Joseph C. Burns et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Deafness and retinal degeneration in a novel USH1C knock-in mouse model

(2010) Jennifer J. Lentz et al.   Developmental Neurobiology

Evolutionary insights into the unique electromotility motor of mammalian outer hair cells

(2010) Oseremen E. Okoruwa et al.   EVOLUTION & DEVELOPMENT

Hearing Impairment: A Panoply of Genes and Functions

(2010) Amiel A. Dror et al.   NEURON

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

(2009) Nicolas Grillet et al.   NEURON

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

(2008) G. Lefevre et al.   DEVELOPMENT

Prestin-Based Outer Hair Cell Motility Is Necessary for Mammalian Cochlear Amplification

(2008) Peter Dallos et al.   NEURON