Article
Cardiac & Cardiovascular Systems
Sergio Raposeiras-Roubin, Marianna Adamo, Xavier Freixa, Dabit Arzamendi, Tomas Benito-Gonzalez, Antonio Montefusco, Isaac Pascual, Luis Nombela-Franco, Josep Rodes-Cabau, Mony Shuvy, Antonio Portoles-Hernandez, Cosmo Godino, Berenice Caneiro-Queija, Laura Lupi, Ander Regueiro, Chin Hion Li, Felipe Fernandez-Vazquez, Simone Frea, Pablo Avanzas, Gabriela Tirado-Conte, Jean-Michel Paradis, Alona Peretz, Vanessa Monivas, Jose A. Baz, Michele Galasso, Luca Branca, Laura Sanchis, Lluis Asmarats, Carmen Garrote-Coloma, Filippo Angelini, Victor Leon, Eduardo Pozo, Alberto Alperi, Ronen Beeri, Dario Cani, Manel Sabate, Estefania Fernandez-Peregrina, Javier Gualis, Pier Paolo Bocchino, Salvatore Curello, Emad Abu-Assi, Andres Iniguez-Romo, Francesco Bedogni, Antonio Popolo Rubbio, Luca Testa, Carmelo Grasso, Rodrigo Estevez-Loureiro
Summary: This study aimed to create and validate a user-friendly score (MitraScore) to predict the risk of mortality in patients undergoing transcatheter edge-to-edge mitral valve repair (TEER). The MitraScore, derived from 8 independent predictors, showed better discrimination and calibration in predicting mortality compared to existing scores. It also demonstrated predictive value for heart failure rehospitalization and correlated with the probability of clinical improvement.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Kaveh Hosseini, Hamidreza Soleimani, Amir Nasrollahizadeh, Yaser Jenab, Angelos Karlas, Dimitrios V. Avgerinos, Alexandros Briasoulis, Toshiki Kuno, Ilias Doulamis, Polydoros N. Kampaktsis
Summary: A comparison of the PASCAL and MitraClip devices showed similar success rates and complication rates for transcatheter edge-to-edge repair (TEER) of the mitral valve. PASCAL was not inferior to MitraClip in reducing the mitral regurgitation (MR) level at discharge.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Guisela Flores, Dolores Mesa, Soledad Ojeda, Javier Suarez de Lezo, Rafael Gonzalez-Manzanares, Guillermo Duenas, Manuel Pan
Summary: The use of transcatheter edge-to-edge repair for mitral regurgitation has increased in recent years. Knowledge of the potential complications related to the procedure is crucial due to its growing popularity. Transesophageal echocardiography plays a key role in guiding the intervention and preventing and diagnosing these complications early.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Nicolas A. Geis, Philipp Schlegel, Markus B. Heckmann, Hugo A. Katus, Norbert Frey, Patricia Crespo Lopez, Philip W. J. Raake
Summary: Transcatheter edge-to-edge repair using the PASCAL or MitraClip device results in favorable and comparable outcomes regarding safety, efficacy, and clinical improvement after 1 year.
Article
Cardiac & Cardiovascular Systems
Leonardo Italia, Marianna Adamo, Laura Lupi, Marta Scodro, Salvatore Curello, Marco Metra
Summary: This review summarizes the effects of RV dysfunction and TR on prognosis in PMVR recipients and the potential impact of PMVR on the right heart. Predictors such as preprocedural tricuspid annular plane systolic excursion, tricuspid annular tissue Doppler S' velocity, and TR severity can be used for patient selection. Additionally, PMVR may lead to improvements in RV function and reduction in TR severity.
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2021)
Review
Cardiac & Cardiovascular Systems
Eduardo Martinez-Gomez, Angela McInerney, Gabriela Tirado-Conte, Jose Alberto de Agustin, Pilar Jimenez-Quevedo, Andres Escudero, Eduardo Pozo Osinalde, Ana Viana-Tejedor, Josebe Goirigolzarri, Luis Marroquin, David Vivas, Carlos Ferrera, Francisco Noriega, Maria Alejandra Restrepo-Cordoba, Nieves Gonzalo, Javier Escaned, Antonio Fernandez-Ortiz, Ignacio Amat-Santos, Rodrigo Estevez-Loureiro, Carlos Macaya, Luis Nombela-Franco
Summary: The study aimed to evaluate the use of MitraClip device in critically ill patients with significant mitral regurgitation. The results showed that percutaneous mitral valve repair with MitraClip is feasible and effective in reducing MR severity and improving outcomes in high-risk patients. Further prospective trials are needed to confirm these findings and determine the true value of MitraClip in hemodynamically unstable patients.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Selena Zhou, Natalia Egorova, Gil Moskowitz, Gennaro Giustino, Gorav Ailawadi, Michael A. Acker, Marc Gillinov, Alan Moskowitz, Annetine Gelijns
Summary: The trend of mitral valve interventions from 2000 to 2016 showed a decrease in mitral valve replacement procedures, an increase in mitral valve repair and MitraClip procedures, with overall improved outcomes despite an increasingly sicker population. Length of stay decreased for all interventions, while comorbidities burden increased. In-hospital mortality also decreased for all interventions, most significantly for MitraClip recipients.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Jie Zeng, Qinglan Shu, Cong Lu, Yi Wang
Summary: This report presents a rare case of a 68-year-old Chinese man with nonobstructive hypertrophic cardiomyopathy and severe mitral valve regurgitation treated with transcatheter edge-to-edge repair (TEER), resulting in significant improvement in symptoms.
Article
Cardiac & Cardiovascular Systems
Trevor Simard, Sreek Vemulapalli, Richard G. Jung, Andrew Vekstein, Amanda Stebbins, David R. Holmes, Andrew Czarnecki, Benjamin Hibbert, Mohamad Alkhouli
Summary: This study investigated the characteristics and outcomes of patients with significant mitral regurgitation and cardiogenic shock who underwent transcatheter edge-to-edge repair (TEER). The results showed that successful reduction of mitral regurgitation in most patients was associated with lower mortality and heart failure hospitalization.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Sepideh Jahanian, Arman Arghami, Erica D. Wittwer, Katherine S. King, Richard C. Daly, Joseph A. Dearani, Phillip G. Rowse, Juan A. Crestanello, Hartzell Schaff
Summary: This study compared patients undergoing mitral valve repair by open sternotomy and minimally invasive surgery, and found that the minimally invasive surgery group had reduced opioid use but slightly higher pain scores postoperatively. Possible explanations include differences in incision site pain and subjective differences in postoperative pain expectations.
ANNALS OF THORACIC SURGERY
(2023)
Article
Medicine, General & Internal
Raj R. Makkar, Joanna Chikwe, Tarun Chakravarty, Qiudong Chen, Patrick T. O'Gara, Marc Gillinov, Michael J. Mack, Andrew Vekstein, Dhairya Patel, Amanda Lee Stebbins, Annetine C. Gelijns, Moody Makar, Deepak L. Bhatt, Samir Kapadia, Sreekanth Vemulapalli, Martin B. Leon
Summary: A cohort study evaluated the outcomes of transcatheter mitral valve repair for degenerative mitral regurgitation, finding a success rate of 88.9%. Among patients with successful repair, those with mild or less residual regurgitation and low mitral gradients had the lowest mortality.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Review
Medicine, General & Internal
Breda Hennessey, Nestor Sabatovicz Jr, Maria Del Trigo
Summary: Acute ischaemic mitral regurgitation (IMR) is a rare and challenging complication following acute myocardial infarction. Despite advancements in surgical and percutaneous interventions, prognosis for patients with acute IMR is often poor. This review focuses on diagnosis, echocardiographic features, and current treatment options for patients with acute IMR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Clemens Metze, Christos Iliadis, Maria I. Koerber, Jennifer von Stein, Marcel Halbach, Stephan Baldus, Roman P. Fister
Summary: This study analyzed the contribution of heart failure to the physical frailty phenotype by examining patients before and after percutaneous mitral valve repair. The results showed that the frequency of frailty decreased after the procedure, and predictors of postprocedural reversibility of frailty were identified.
JACC-HEART FAILURE
(2023)
Review
Cardiac & Cardiovascular Systems
Rasha Kaddoura, Sanket Bhattarai, Dina Abushanab, Mohammed Al-Hijji
Summary: This systematic review and meta-analysis compared the long-term morbidity and mortality of percutaneous mitral valve repair (PMVr) using MitraClip to surgery or medical therapy for mitral valve regurgitation. The results showed that within 12 months of follow-up, PMVr did not have a significant advantage in maintaining mitral valve regurgitation grade 2+ or symptom-free heart failure compared to surgery. However, compared to medical therapy, PMVr significantly reduced all-cause mortality at 12 and >= 24 months of follow-up.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Tanya Salvatore, Fabrizio Ricci, George D. Dangas, Bushra S. Rana, Laura Ceriello, Luca Testa, Mohammed Y. Khanji, Anna Laura Caterino, Corrado Fiore, Antonio Popolo Rubbio, Marianna Appignani, Maria Di Fulvio, Francesco Bedogni, Sabina Gallina, Marco Zimarino
Summary: Secondary mitral regurgitation occurs in patients with heart failure and left ventricular dysfunction, independently associated with poor outcome. MitraClip through percutaneous mitral valve repair is highly effective in reducing MR in HF patients, but the clinical benefit remains controversial.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)