The taste of toxicity: A quantitative analysis of bitter and toxic molecules

Extraoral bitter taste receptors in health and disease

(2017) Ping Lu et al.   JOURNAL OF GENERAL PHYSIOLOGY

Bitter or not? BitterPredict, a tool for predicting taste from chemical structure

(2017) Ayana Dagan-Wiener et al.   Scientific Reports

The impact of hop bitter acid and polyphenol profiles on the perceived bitterness of beer

(2016) Olayide Oladokun et al.   FOOD CHEMISTRY

Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans

(2016) Kristina Lossow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promiscuity and selectivity of bitter molecules and their receptors

(2015) Antonella Di Pizio et al.   BIOORGANIC & MEDICINAL CHEMISTRY

TAS2R bitter taste receptors regulate thyroid function

(2015) Adam A. Clark et al.   FASEB JOURNAL

Taste of medicinal plants: A potential tool in predicting ethnopharmacological activities?

(2015) Marilena Gilca et al.   JOURNAL OF ETHNOPHARMACOLOGY

Taste receptors in innate immunity

(2014) Robert J. Lee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

T3DB: the toxic exposome database

(2014) David Wishart et al.   NUCLEIC ACIDS RESEARCH

One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade

(2013) Bruno O. Villoutreix et al.   DRUG DISCOVERY TODAY

The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14

(2013) Anat Levit et al.   FASEB JOURNAL

Bitter Taste Receptor Activation by Flavonoids and Isoflavonoids: Modeled Structural Requirements for Activation of hTAS2R14 and hTAS2R39

(2013) Wibke S. U. Roland et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Extraoral bitter taste receptors as mediators of off-target drug effects

(2012) Adam A. Clark et al.   FASEB JOURNAL

T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection

(2012) Robert J. Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional characterization of bitter-taste receptors expressed in mammalian testis

(2012) J. Xu et al.   MOLECULAR HUMAN REPRODUCTION

Functional bitter taste receptors are expressed in brain cells

(2011) Nisha Singh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BitterDB: a database of bitter compounds

(2011) Ayana Wiener et al.   NUCLEIC ACIDS RESEARCH

Cholinergic chemosensory cells in the trachea regulate breathing

(2011) G. Krasteva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of Absolute Solvation Free Energies using Molecular Dynamics Free Energy Perturbation and the OPLS Force Field

(2010) Devleena Shivakumar et al.   Journal of Chemical Theory and Computation

Caffeine (1, 3, 7-trimethylxanthine) in Foods: A Comprehensive Review on Consumption, Functionality, Safety, and Regulatory Matters

(2010) Melanie A. Heckman et al.   JOURNAL OF FOOD SCIENCE

Analysis and comparison of 2D fingerprints: Insights into database screening performance using eight fingerprint methods

(2010) Jianxin Duan et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

(2010) Deepak A Deshpande et al.   NATURE MEDICINE

Green Tea Polyphenols and Cancer: Biologic Mechanisms and Practical Implications

(2010) Nihal Ahmad et al.   NUTRITION REVIEWS

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

T3DB: a comprehensively annotated database of common toxins and their targets

(2009) Emilia Lim et al.   NUCLEIC ACIDS RESEARCH

Herbivore induction of the glucosinolate–myrosinase defense system: major trends, biochemical bases and ecological significance

(2008) Susanne Textor et al.   PHYTOCHEMISTRY REVIEWS

Estimation of acute oral toxicity using the No Observed Adverse Effect Level (NOAEL) from the 28 day repeated dose toxicity studies in rats

(2008) Anna Bulgheroni et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY