Article
Medicine, General & Internal
Carlos Roncero, Joselin Perez, Jesus Molina, Jose Antonio Quintano, Ana Isabel Campuzano, Javier Perez, Marc Miravitlles
Summary: This study aims to investigate the prevalence of suicidal ideation in patients with chronic obstructive pulmonary disease (COPD) and its association with demographic and clinical variables. The study found that suicidal ideation is common in COPD patients, especially in women. Severe depression is significantly associated with the occurrence of suicidal ideation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Chien-Chia Huang, Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Chia-Hsiang Fu, Ta-Jen Lee
Summary: This study aimed to investigate depression- and anxiety-associated psychological symptoms in patients with empty nose syndrome (ENS) before and after surgical reconstruction, and to compare them with those of control subjects. The results showed that patients with ENS experienced significant improvement in nasal and psychological evaluations after surgery, but both were still significantly greater than those in the control group. Preoperative BDI-II and BAI scores were significant predictors of postoperative residual psychological symptoms.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Francisco Javier Ruiz-Sanchez, Maria do Rosario Martins, Salete Soares, Carlos Romero-Morales, Daniel Lopez-Lopez, Juan Gomez-Salgado, Ana Maria Jimenez-Cebrian
Summary: This study examined the level of depression in patients with multiple sclerosis (MS) compared to a healthy population. The findings showed that MS patients had higher levels of depression, indicating a negative impact on their quality of life.
Article
Health Care Sciences & Services
Chien-Hung Lin, Shih-Ting Tseng, Yao-Chung Chuang, Chun-En Kuo, Nai-Ching Chen
Summary: The study found that grounding significantly improved sleep quality among patients with mild AD, but did not have a significant impact on anxiety and depression symptoms.
Article
Peripheral Vascular Disease
Wei-Chung Tsai, Wen-Hsien Lee, Ying-Chih Chen, Yi-Hsueh Liu, Ching-Tang Chang, Po-Chao Hsu, Chun-Yuan Chu, Tsung-Hsien Lin, Chee-Siong Lee, Chien-Hung Lee, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu, Ho-Ming Su
Summary: Combining low ABI and high ABID to create an ABI score has shown significant predictive ability for overall and cardiovascular mortality, outperforming other ABI-related multivariable models in predicting mortality.
HYPERTENSION RESEARCH
(2021)
Article
Psychiatry
Ana Maria Jimenez-Cebrian, Patricia Palomo-Lopez, Ricardo Becerro-de-Bengoa Vallejo, Marta Elena Losa-Iglesias, Emmanuel Navarro-Flores, Marta San-Antolin, Cesar Calvo-Lobo, Daniel Lopez-Lopez
Summary: The study aimed to assess the impact of depression in adult patients with hemophilia and compare it with healthy matched-paired controls.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Dermatology
Hamza Yildiz, Serkan Zincir
Summary: This study investigated the comorbidity of depression and anxiety in patients with patchy AA and compared it with a healthy control group. The results showed that depression and anxiety were more prevalent in patients with AA compared to healthy volunteers. Dermatologists should consider psychiatric diseases like depression and anxiety when diagnosing AA.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Clinical Neurology
Minho Han, Young Dae Kim, Ilhyung Lee, Hyungwoo Lee, Joonnyung Heo, Hye Sun Lee, Hyo Suk Nam
Summary: The study found that the toe-brachial index (TBI) is associated with poor prognosis in stroke patients, even in those with normal ankle-brachial index (ABI). Low TBI is independently associated with poor short- and long-term outcomes in acute ischemic stroke patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Anna Zalewska, Monika Galczyk, Katarzyna Van Damme-Ostapowicz
Summary: The study found that about every fourth person in Poland experienced moderate to severe depressive symptoms during the COVID-19 pandemic. Women had higher mean depression scores, and there were significant correlations between age and depression measures in men. Asymptomatic individuals had the lowest levels of depression, while those with severe symptoms had major depressive disorder.
Article
Microbiology
Jana Hlavacova, Jaroslav Flegr, Katerina Fiuraskova, Sarka Kankova
Summary: The study revealed opposite effects of latent Toxoplasma infection on depression in men and women. Specifically, women with Toxoplasma had higher depression scores compared to Toxoplasma-negative women, while the reverse was true for men. The results may be attributed to gender differences in reactions to chronic stress associated with lifelong infection.
Article
Psychiatry
Satoshi Yokoyama, Go Okada, Koki Takagaki, Eri Itai, Kohei Kambara, Yuki Mitsuyama, Hotaka Shinzato, Yoshikazu Masuda, Ran Jinnin, Yasumasa Okamoto
Summary: This study examined the network structure of depressive symptoms in different depressive states and found that current depression has a stronger and denser network compared to nonclinical groups. Interestingly, remitted depression reached a similar level as healthy controls but still retained the same network structure as current depression, indicating traces of depression. The findings provide insights into the development and formation of depression.
EUROPEAN PSYCHIATRY
(2022)
Article
Clinical Neurology
Andreas Hostmaelingen, Pal Ulvenes, Helene Amundsen Nissen-Lie, Mikkel Eielsen, Bruce E. Wampold
Summary: This study examined the factor structure of the Beck Depression Inventory-II in inpatient treatment patients with chronic depression, revealing a two-factor solution with stability and invariance across primary diagnosis and comorbidity. The findings suggest implications for clinicians in treatment choices for patients with chronic depression.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Ahmed Esmael, Mohamed Elsherif, Mohamed Elegezy, Hosam Egilla
Summary: Patients with neurobrucellosis exhibit cognitive impairment and more psychiatric symptoms, such as behavioral changes, anxiety, and depression, compared to those with non-neurobrucellosis. It is important to consider the diagnosis and treatment of neurobrucellosis in patients with neuropsychiatric manifestations.
NEUROLOGICAL RESEARCH
(2021)
Article
Geriatrics & Gerontology
Georgios Papazisis, Ioannis Tsakiridis, Alexandra Ainatzoglou, Athanasia Pappa, Thalia Bellali, Dimitrios Kouvelas, Themistoklis Dagklis
Summary: The study found that more than one in four post-menopausal women in Greece screened positive for symptoms indicative of depression, with a personal history of depression, age < 55 years, smoking, and current working status being identified as independent predictors of its emergence.
Article
Clinical Neurology
Gianpaolo Maggi, Alfonsina D'Iorio, Edoardo Nicolo Aiello, Barbara Poletti, Nicola Ticozzi, Vincenzo Silani, Marianna Amboni, Carmine Vitale, Gabriella Santangelo
Summary: This study assessed the psychometric and diagnostic properties of the Beck Depression Inventory-II (BDI-II) in an Italian Parkinson's disease (PD) cohort. The results showed that the BDI-II performed well in terms of internal consistency and construct validity, making it a reliable tool for screening depression in PD patients.
NEUROLOGICAL SCIENCES
(2023)
Letter
Medicine, General & Internal
How-Ran Guo, Sheng-Yow Ho
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2021)
Article
Endocrinology & Metabolism
Hui-Teng Cheng, Xiaoqi Xu, Paik Seong Lim, Kuan-Yu Hung
Summary: The study compared the incidence of diabetes-related end-stage renal disease globally from 2000 to 2015, finding significant geographic variation in the risk of diabetic patients reaching ESRD in different regions during the study period.
Article
Urology & Nephrology
Wan-Chuan Tsai, Hon-Yen Wu, Yen-Ling Chiu, Ju-Yeh Yang, Mei-Fen Pai, Yong-Ru Wu, Wan-Yu Lin, Kuan-Yu Hung, Kuo-Liong Chien, Shih-Ping Hsu, Yu-Sen Peng
Summary: The study found that increased dietary phosphorus intake rapidly increases serum phosphate, iPTH, and iFGF23 levels, and decreases serum calcium levels, highlighting the important role of daily fluctuations in dietary habits in disturbed mineral homeostasis in hemodialysis patients.
Article
Clinical Neurology
Yun-Wen Chiao, Hanoch Livneh, How-Ran Guo, Wei-Jen Chen, Ming-Chi Lu, Miao-Chiu Lin, Chia-Chou Yeh, Tzung-Yi Tsai
Summary: This study aimed to investigate the effect of Chinese herbal medicines (CHMs) on the risk of depression among individuals with insomnia. The findings demonstrated that adding CHMs to conventional treatment significantly reduces depression risk among patients with insomnia.
FRONTIERS IN NEUROLOGY
(2021)
Review
Toxicology
Rong-Jane Chen, Yu-Hsuan Lee, Tzu-Hao Chen, Yu-Ying Chen, Ya-Ling Yeh, Ching-Ping Chang, Chien-Cheng Huang, How-Ran Guo, Ying-Jan Wang
Summary: Carbon monoxide, known as a silent killer, can reduce oxygen carrying capacity in the body by binding to hemoglobin. While toxic at high concentrations, CO has cyto- and tissue-protective effects at low concentrations, modulating inflammatory responses through regulation of cytokine production. Understanding the interplay between mitochondria, autophagy, exosomes, and the inflammasome is crucial for understanding the health effects of CO and potential treatment strategies for inflammation-related diseases.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Chia-Ter Chao, Szu-Ying Lee, Jui Wang, Kuo-Liong Chien, Kuan-Yu Hung
Summary: Patients with incident diabetes and subsequently developed chronic kidney disease had a significantly higher risk of mortality, heart failure, acute myocardial infarction, and peripheral vascular disease compared to those without CKD. The risk of mortality, heart failure, and acute myocardial infarction associated with CKD became significant soon after diabetes occurred and remained significant throughout follow-up, indicating the need for early cardiovascular care strategies for newly diagnosed diabetic patients.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Urology & Nephrology
Chia-Ter Chao, Ching- Chang, Pa-Chun Wang, Ching-Feng Chiang, Chia-Pei Chen, Hui-Shu Hsu, Kuan-Yu Hung
Summary: This study found that a kidney-care DSC certification program significantly improved multiple performance indicators of participating institutes, including patients' haemoglobin, albumin, and shunt re-creation probability among patients with end-stage renal disease.
Article
Environmental Sciences
Shu-Yuan Wang, Ya-Yun Cheng, How-Ran Guo, Yen-Cheng Tseng
Summary: A study in Taiwan found that prenatal exposure to carbon monoxide and nitrogen dioxide was associated with an increased risk of developing ASD. The research showed that exposure to CO and NO2 in all three trimesters were linked to higher risks of ASD.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Ying-Fong Ker, Perng-Jy Tsai, How-Ran Guo
Summary: The study demonstrates that when a study population is relatively healthier, proportional mortality ratios (PMRs) are more appropriate than mortality ratios in assessing risk, as they can detect increases in mortality. In the case of workers exposed to acid mists, PMRs revealed elevated risks for cancer, especially stomach cancer, indicating potential carcinogenic effects of low-level acid mist exposures on the stomach.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Cardiac & Cardiovascular Systems
Peir-Haur Hung, Chih-Ching Yeh, Chih-Yen Hsiao, Chih-Hsin Muo, Kuan-Yu Hung, Kuen-Jer Tsai
Summary: For patients receiving hemodialysis, the use of erythropoietin is not associated with an increased risk of stroke or any of its subtypes.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Biochemistry & Molecular Biology
Chong-Sun Khoi, Yu-Wen Lin, Jia-Huang Chen, Biing-Hui Liu, Tzu-Yu Lin, Kuan-Yu Hung, Chih-Kang Chiang
Summary: This study demonstrates that OTA induces nephrotoxicity through ER stress-related apoptosis in human renal cells, with a pathway mediated by ROS.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Chong-Sun Khoi, Jia-Huang Chen, Tzu-Yu Lin, Chih-Kang Chiang, Kuan-Yu Hung
Summary: OTA is a mycotoxin widely found in various foods and feeds, causing harmful effects on humans and animals, with the kidneys being the main target. Recent research has focused on the intracellular molecular interactions and signaling pathways of OTA-induced nephrotoxicity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Environmental Sciences
Bo-Lei Chen, Ya-Yun Cheng, Cheng-Yu Lin, How-Ran Guo
Summary: This study examines the risk of voice disorders in private school teachers in Taiwan. The results show that private school teachers have a higher risk of developing voice disorders compared to other occupations, and this risk is especially higher for elementary and high-school teachers. This study supports the causal relationship between occupation and voice disorders in teachers.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Chong-Sun Khoi, Cai-Qin Xiao, Kuan-Yu Hung, Tzu-Yu Lin, Chih-Kang Chiang
Summary: This study investigated the mechanism of vascular dysfunction induced by palmitic acid, and revealed the crucial roles of XBP1s and OSGIN1 in maintaining endothelial cell migration and regulating autophagy.
Article
Cell Biology
Jia-Huang Chen, Chia-Hsien Wu, Jia-Rong Jheng, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung, Shing-Hwa Liu, Chih-Kang Chiang
Summary: This study investigated the role of XBP1, a key regulator of the unfolded protein response (UPR), in the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). The findings demonstrated that XBP1 expression was attenuated after AKI and inversely correlated with the severity of renal fibrosis. XBP1 deficiency in mice resulted in exacerbated renal fibrosis. Silencing XBP1 in human proximal tubular epithelial cells led to cell cycle arrest and increased TGF-beta 1 secretion. The study also identified TNF receptor associated protein 1 (Trap1) as a potential downstream target of XBP1, and showed that Trap1 overexpression alleviated the profibrotic effects of XBP1 deficiency.
JOURNAL OF BIOMEDICAL SCIENCE
(2022)