Preconditioning of primary human renal proximal tubular epithelial cells without tryptophan increases survival under hypoxia by inducing autophagy

Indoleamine 2,3-dioxygenase, by degrading L-tryptophan, enhances carnitine palmitoyltransferase I activity and fatty acid oxidation, and exerts fatty acid-dependent effects in human alloreactive CD4+ T-cells

(2016) Theodoros Eleftheriadis et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Mitochondrial metabolic remodeling in response to genetic and environmental perturbations

(2016) Kate E.R. Hollinshead et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Autophagy is activated to protect against endotoxic acute kidney injury

(2016) Shuqin Mei et al.   Scientific Reports

Autophagy Protects Renal Tubular Cells Against Ischemia / Reperfusion Injury in a Time-Dependent Manner

(2015) Xuejing Guan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Amino Acid Metabolism Inhibits Antibody-Driven Kidney Injury by Inducing Autophagy

(2015) Kapil Chaudhary et al.   JOURNAL OF IMMUNOLOGY

Regulation of G1 Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2α Phosphorylation

(2015) Yan Liu et al.   NEOPLASIA

Indoleamine 2,3-dioxygenase increases p53 levels in alloreactive human T cells, and both indoleamine 2,3-dioxygenase and p53 suppress glucose uptake, glycolysis and proliferation

(2014) T. Eleftheriadis et al.   INTERNATIONAL IMMUNOLOGY

FGF21 is an endocrine signal of protein restriction

(2014) Thomas Laeger et al.   JOURNAL OF CLINICAL INVESTIGATION

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR

(2013) Jordan Gallinetti et al.   BIOCHEMICAL JOURNAL

Autophagy regulation by nutrient signaling

(2013) Ryan C Russell et al.   CELL RESEARCH

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

(2013) Wafa B’chir et al.   NUCLEIC ACIDS RESEARCH

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury

(2012) Shuya Liu et al.   Autophagy

Tryptophan Depletion and the Kinase GCN2 Mediate IFN- -Induced Autophagy

(2012) S. Fougeray et al.   JOURNAL OF IMMUNOLOGY

Autophagy in proximal tubules protects against acute kidney injury

(2012) Man Jiang et al.   KIDNEY INTERNATIONAL

Surgical Stress Resistance Induced by Single Amino Acid Deprivation Requires Gcn2 in Mice

(2012) W. Peng et al.   Science Translational Medicine

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy Protects the Proximal Tubule from Degeneration and Acute Ischemic Injury

(2011) T. Kimura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3

(2011) N. H. Kwon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-Reperfusion Injury

(2010) Man Jiang et al.   AMERICAN JOURNAL OF PATHOLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

p53 at a glance

(2010) C. A. Brady et al.   JOURNAL OF CELL SCIENCE

Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation

(2010) V. M. Hubbard et al.   JOURNAL OF IMMUNOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Long-term Risk of Mortality and Other Adverse Outcomes After Acute Kidney Injury: A Systematic Review and Meta-analysis

(2009) Steven G. Coca et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

PCAF is an HIF-1α cofactor that regulates p53 transcriptional activity in hypoxia

(2008) G Xenaki et al.   ONCOGENE