Host defenses against metabolic endotoxaemia and their impact on lipopolysaccharide detection

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

(2016) Tommi Vatanen et al.   CELL

Chasing a ghost? – Issues with the determination of circulating levels of endotoxin in human blood

(2016) Anne Gnauck et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Reduced dietary intake of pro-inflammatory Toll-like receptor stimulants favourably modifies markers of cardiometabolic risk in healthy men

(2016) M. Herieka et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Protein tyrosine phosphatase-1B contributes to LPS-induced leptin resistance in male rats

(2015) Beatriz de Carvalho Borges et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Small intestinal bacterial overgrowth and toll-like receptor signaling in patients with non-alcoholic fatty liver disease

(2015) Shweta Kapil et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Limulus Amebocyte Lysate assay may be unsuitable for detecting endotoxin in blood of healthy female subjects

(2015) Anne Gnauck et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Immune Responses to O-Specific Polysaccharide and Lipopolysaccharide of Vibrio cholerae O1 Ogawa in Adult Bangladeshi Recipients of an Oral Killed Cholera Vaccine and Comparison to Responses in Patients with Cholera

(2014) Taher Uddin et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Plasma Lipopolysaccharide Is Closely Associated With Glycemic Control and Abdominal Obesity: Evidence from bariatric surgery

(2013) M. Troseid et al.   DIABETES CARE

The Structural Basis for Endotoxin-induced Allosteric Regulation of the Toll-like Receptor 4 (TLR4) Innate Immune Receptor

(2013) Teresa Paramo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal alkaline phosphatase prevents metabolic syndrome in mice

(2013) K. Kaliannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages

(2012) Dowty Movita et al.   JOURNAL OF LEUKOCYTE BIOLOGY

High Fat Diet-Induced Gut Microbiota Exacerbates Inflammation and Obesity in Mice via the TLR4 Signaling Pathway

(2012) Kyung-Ah Kim et al.   PLoS One

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

(2012) U. Ohto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endotoxemia Is Associated With an Increased Risk of Incident Diabetes

(2011) P. J. Pussinen et al.   DIABETES CARE

E. coli Lipopolysaccharide: Acute oral toxicity study in mice

(2011) Marc S. Harper et al.   FOOD AND CHEMICAL TOXICOLOGY

Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection

(2011) A. Haas et al.   GUT

Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin

(2011) Baomei Shao et al.   HEPATOLOGY

Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression

(2010) Husam Ghanim et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Alternative Pathway Is Critical for Pathogenic Complement Activation in Endotoxin- and Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2010) Talat H. Malik et al.   CIRCULATION

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Endogenous ligands of TLR2 and TLR4: agonists or assistants?

(2010) Clett Erridge   JOURNAL OF LEUKOCYTE BIOLOGY

ABCA1 promotes the efflux of bacterial LPS from macrophages and accelerates recovery from LPS-induced tolerance

(2010) Patricia A. Thompson et al.   JOURNAL OF LIPID RESEARCH

Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation

(2010) Fabienne Laugerette et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Changes in endotoxin levels in T2DM subjects on anti-diabetic therapies

(2009) Omar S Al-Attas et al.   Cardiovascular Diabetology

Experimental Endotoxemia Induces Adipose Inflammation and Insulin Resistance in Humans

(2009) N. N. Mehta et al.   DIABETES

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice

(2009) Astrid Spruss et al.   HEPATOLOGY

Structural prerequisites for endotoxic activity in the Limulus test as compared to cytokine production in mononuclear cells

(2009) T. Gutsmann et al.   Innate Immunity

Bacteroides fragilis signals through Toll-like receptor (TLR) 2 and not through TLR4

(2009) M. Alhawi et al.   JOURNAL OF MEDICAL MICROBIOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Failure of oralE. coliO83 lipopolysaccharide to influence intestinal morphology and cell proliferation in rats: Short communication

(2008) György Illyés et al.   ACTA VETERINARIA HUNGARICA

Endotoxemia is Related to Systemic Inflammation and Atherosclerosis in Peritoneal Dialysis Patients

(2008) C.-C. Szeto et al.   Clinical Journal of the American Society of Nephrology

Continuous pharmacodynamic activity of eritoran tetrasodium, a TLR4 antagonist, during intermittent intravenous infusion into normal volunteers

(2008) Daniel P. Rossignol et al.   Innate Immunity

SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance

(2008) Lei Cai et al.   JOURNAL OF CLINICAL INVESTIGATION

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH

Effect of short-term intralipid infusion on the immune response during low-dose endotoxemia in humans

(2007) Rikke Krogh-Madsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Antiinflammatory and Antiatherogenic Effects of the NF-κB Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE −/− Mice

(2007) Clarisse Cuaz-Pérolin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY