Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity

Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

(2016) Marika Ziętak et al.   Cell Metabolism

Mitochondria-targeted dodecyltriphenylphosphonium (C12TPP) combats high-fat-diet-induced obesity in mice

(2016) A V Kalinovich et al.   INTERNATIONAL JOURNAL OF OBESITY

Obesity but not high-fat diet impairs lymphatic function

(2016) G D García Nores et al.   INTERNATIONAL JOURNAL OF OBESITY

miR-200a regulates Rheb-mediated amelioration of insulin resistance after duodenal–jejunal bypass

(2016) W Guo et al.   INTERNATIONAL JOURNAL OF OBESITY

Synergism between NF-kappa B inhibitor, celastrol, and XIAP inhibitor, embelin, in an acute myeloid leukemia cell line, HL-60

(2016) HosseinZarei Jaliani et al.   Journal of Cancer Research and Therapeutics

Embelin inhibits proliferation, induces apoptosis and alters gene expression profiles in breast cancer cells

(2016) Priyank Shah et al.   Pharmacological Reports

Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes

(2016) Sergio Rodriguez-Cuenca et al.   PLoS One

Gut Microbiota Orchestrates Energy Homeostasis during Cold

(2015) Claire Chevalier et al.   CELL

Molecular Pathways: Fatty Acid Synthase

(2015) S. F. Jones et al.   CLINICAL CANCER RESEARCH

miR-20a regulates adipocyte differentiation by targeting lysine-specific demethylase 6b and transforming growth factor-β signaling

(2015) J Zhou et al.   INTERNATIONAL JOURNAL OF OBESITY

Embelin-Induced Apoptosis of Human Prostate Cancer Cells Is Mediated through Modulation of Akt and β-Catenin Signaling

(2015) Nahee Park et al.   PLoS One

miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop

(2015) Xiaohui Guan et al.   STEM CELLS

miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling

(2015) Xin Zhang et al.   Scientific Reports

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat

(2015) Kangxing Song et al.   Oncotarget

Embelin inhibits pancreatic cancer progression by directly inducing cancer cell apoptosis and indirectly restricting IL-6 associated inflammatory and immune suppressive cells11These authors contributed equally to this work.

(2014) Meiyu Peng et al.   CANCER LETTERS

Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

(2014) Deepa R. Avisetti et al.   PLoS One

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin

(2013) Anja M. Schaible et al.   BIOCHEMICAL PHARMACOLOGY

Embelin accelerates cutaneous wound healing in diabetic rats

(2013) Pradeep T. Deshmukh et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Multicomponent Synthesis of Antibacterial Dihydropyridin and Dihydropyran Embelin Derivatives

(2013) Rosalyn Peña et al.   JOURNAL OF ORGANIC CHEMISTRY

Anti-tumor activity of the X-linked inhibitor of apoptosis (XIAP) inhibitor embelin in gastric cancer cells

(2013) Da-Guang Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Embelin Suppresses Dendritic Cell Functions and Limits Autoimmune Encephalomyelitis Through the TGF-β/β-catenin and STAT3 Signaling Pathways

(2013) Zhenyi Xue et al.   MOLECULAR NEUROBIOLOGY

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

(2013) Morgan D Fullerton et al.   NATURE MEDICINE

Anti-diabetic activity of embelin: Involvement of cellular inflammatory mediators, oxidative stress and other biomarkers

(2013) Suresh R. Naik et al.   PHYTOMEDICINE

miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6

(2013) J Wang et al.   Cell Death & Disease

Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats

(2012) Gopalsamy Rajiv Gandhi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans

(2012) Birgit Gustafson et al.   DIABETES

Instruction of mesenchymal cell fate by the transcription factor C/EBPβ

(2012) Jeske J. Smink et al.   GENE

Preventive Effect of Embelin fromEmbelia ribeson Lipid Metabolism and Oxidative Stress in High-Fat Diet-Induced Obesity in Rats

(2012) Hemantkumar Chaudhari et al.   PLANTA MEDICA

Antioxidant activity and protection of pancreaticβ-cells by embelin in streptozotocin-induced diabetes

(2012) Rajnish GUPTA et al.   Journal of Diabetes

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

(2011) Ji Young Heo et al.   CANCER LETTERS

Wnt signaling and adipocyte lineage commitment

(2011) Robert R. Bowers et al.   CELL CYCLE

Synthesis and Evaluation of Analgesic and Anti-inflammatory Activities of Most Active Free Radical Scavenging Derivatives of Embelin—A Structure–Activity Relationship

(2011) Sekar Mahendran et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Protective Effect of Embelin from Embelia ribes Burm. Against Transient Global Ischemia-Induced Brain Damage in Rats

(2011) B. S. Thippeswamy et al.   NEUROTOXICITY RESEARCH

Transcriptional networks and chromatin remodeling controlling adipogenesis

(2011) Rasmus Siersbæk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

An allostatic control of membrane lipid composition by SREBP1

(2010) Rachel M. Hagen et al.   FEBS LETTERS

Effects of Embelin on Lipid Peroxidation and Free Radical Scavenging Activity against Liver Damage in Rats

(2009) Dharmendra Singh et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Misexpression of CCAAT/enhancer binding protein beta causes osteopenia

(2009) Stefano Zanotti et al.   JOURNAL OF ENDOCRINOLOGY