Adolescent Alcohol Exposure-Induced Changes in Alpha-Melanocyte Stimulating Hormone and Neuropeptide Y Pathways via Histone Acetylation in the Brain During Adulthood

Intra-cerebral and intra-nasal melanocortin-4 receptor antagonist blocks withdrawal hyperalgesia in alcohol-dependent rats

(2016) Emily A. Roltsch Hellard et al.   ADDICTION BIOLOGY

A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood

(2016) Amul J. Sakharkar et al.   Brain Structure & Function

Adolescent Alcohol Exposure: Burden of Epigenetic Reprogramming, Synaptic Remodeling, and Adult Psychopathology

(2016) Evan J. Kyzar et al.   Frontiers in Neuroscience

Lateral hypothalamic melanocortin receptor signaling modulates binge-like ethanol drinking in C57BL/6J mice

(2015) Gretchen M. Sprow et al.   ADDICTION BIOLOGY

Comparative effects of intranasal neuropeptide Y and HS014 in preventing anxiety and depressive-like behavior elicited by single prolonged stress

(2015) Esther L. Sabban et al.   BEHAVIOURAL BRAIN RESEARCH

A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation

(2015) Benoit Laurent et al.   MOLECULAR CELL

Potential role of adolescent alcohol exposure-induced amygdaloid histone modifications in anxiety and alcohol intake during adulthood

(2015) Subhash C. Pandey et al.   NEUROBIOLOGY OF DISEASE

Molecular mechanisms of synaptic remodeling in alcoholism

(2015) Evan J. Kyzar et al.   NEUROSCIENCE LETTERS

Binge ethanol exposure during adolescence leads to a persistent loss of neurogenesis in the dorsal and ventral hippocampus that is associated with impaired adult cognitive functioning

(2015) Ryan P. Vetreno et al.   Frontiers in Neuroscience

Alpha-melanocyte stimulating hormone modulates ethanol self-administration in posterior ventral tegmental area through melanocortin-4 receptors

(2014) Gajanan P. Shelkar et al.   ADDICTION BIOLOGY

Adolescent Alcohol Exposure Alters GABAAReceptor Subunit Expression in Adult Hippocampus

(2014) Samuel W. Centanni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories

(2014) Johannes Gräff et al.   CELL

Effects of acute ethanol exposure on anxiety measures and epigenetic modifiers in the extended amygdala of adolescent rats

(2014) Amul J. Sakharkar et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

MOLECULAR EVOLUTION OF GPCRS: Melanocortin/melanocortin receptors

(2014) Robert M Dores et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Blockage of melanocortin-4 receptors by intranasal HS014 attenuates single prolonged stress-triggered changes in several brain regions

(2014) Lidia I. Serova et al.   JOURNAL OF NEUROCHEMISTRY

Adolescent alcohol exposure and persistence of adolescent-typical phenotypes into adulthood: A mini-review

(2014) Linda Patia Spear et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Adolescent, but Not Adult, Binge Ethanol Exposure Leads to Persistent Global Reductions of Choline Acetyltransferase Expressing Neurons in Brain

(2014) Ryan P. Vetreno et al.   PLoS One

Targeting central melanocortin receptors: a promising novel approach for treating alcohol abuse disorders

(2014) Jeffrey J. Olney et al.   Frontiers in Neuroscience

Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress

(2013) Lidia I. Serova et al.   BEHAVIOURAL BRAIN RESEARCH

Aberrant Histone Deacetylase2–Mediated Histone Modifications and Synaptic Plasticity in the Amygdala Predisposes to Anxiety and Alcoholism

(2013) Sachin Moonat et al.   BIOLOGICAL PSYCHIATRY

Addiction as a stress surfeit disorder

(2013) George F. Koob et al.   NEUROPHARMACOLOGY

Adolescent binge-like ethanol exposure reduces basal α-MSH expression in the hypothalamus and the amygdala of adult rats

(2013) Jose Manuel Lerma-Cabrera et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Extreme Binge Drinking Among 12th-Grade Students in the United States

(2013) Megan E. Patrick et al.   JAMA Pediatrics

Male Germline Transmits Fetal Alcohol Adverse Effect on Hypothalamic Proopiomelanocortin Gene Across Generations

(2012) Dmitry Govorko et al.   BIOLOGICAL PSYCHIATRY

Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens

(2012) Byung Kook Lim et al.   NATURE

Neuropeptide Y (NPY) in the extended amygdala is recruited during the transition to alcohol dependence

(2012) Nicholas W. Gilpin   NEUROPEPTIDES

Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens

(2012) Stéphanie Alaux-Cantin et al.   NEUROPHARMACOLOGY

Central Neuropeptide Y Modulates Binge-Like Ethanol Drinking in C57BL/6J Mice via Y1 and Y2 Receptors

(2012) Angela M Sparrow et al.   NEUROPSYCHOPHARMACOLOGY

Adolescent Binge Drinking Leads to Changes in Alcohol Drinking, Anxiety, and Amygdalar Corticotropin Releasing Factor Cells in Adulthood in Male Rats

(2012) Nicholas W. Gilpin et al.   PLoS One

Histone Deacetylases (HDAC)-Induced Histone Modifications in the Amygdala: A Role in Rapid Tolerance to the Anxiolytic Effects of Ethanol

(2011) Amul J. Sakharkar et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Periadolescent ethanol exposure reduces adult forebrain ChAT+IR neurons: correlation with behavioral pathology

(2011) C.L. Ehlers et al.   NEUROSCIENCE

Research on alcohol and adolescent brain development: opportunities and future directions

(2010) Ellen D. Witt   ALCOHOL

Knocking down the transcript of protein kinase C-lambda modulates hypothalamic glutathione peroxidase, melanocortin receptor and neuropeptide Y gene expression in amphetamine-treated rats

(2010) Yih-Shou Hsieh et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Involvement of α-MSH in the social isolation induced anxiety- and depression-like behaviors in rat

(2010) Dadasaheb M. Kokare et al.   NEUROPHARMACOLOGY

Neuropeptide Y Signaling in the Central Nucleus of Amygdala Regulates Alcohol-Drinking and Anxiety-Like Behaviors of Alcohol-Preferring Rats

(2009) Huaibo Zhang et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Melanocortin activity in the amygdala controls appetite for dietary fat

(2009) Stéphane Boghossian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Brain stress systems in the amygdala and addiction

(2009) George F. Koob   BRAIN RESEARCH

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Neuropeptide Y suppresses ethanol drinking in ethanol-abstinent, but not non–ethanol-abstinent, Wistar rats

(2008) Nicholas W. Gilpin et al.   ALCOHOL

Involvement of alpha-melanocyte stimulating hormone (α-MSH) in differential ethanol exposure and withdrawal related depression in rat: Neuroanatomical–behavioral correlates

(2008) Dadasaheb M. Kokare et al.   BRAIN RESEARCH

Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat

(2008) Maria Pascual et al.   JOURNAL OF NEUROCHEMISTRY

Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

A Role for Brain Stress Systems in Addiction

(2008) George F. Koob   NEURON

Neuropeptide Y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking

(2008) Nicholas W. Gilpin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE