Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer

GLUT1 and ASCT2 as Predictors for Prognosis of Hepatocellular Carcinoma

(2017) Hong-Wei Sun et al.   PLoS One

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

(2016) Shawn M. Davidson et al.   Cell Metabolism

SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate

(2016) Chi Chun Wong et al.   GASTROENTEROLOGY

Clinicopathological significance of LAT1 and ASCT2 in patients with surgically resected esophageal squamous cell carcinoma

(2016) Hiroaki Honjo et al.   JOURNAL OF SURGICAL ONCOLOGY

Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer

(2016) Yujun Hao et al.   Nature Communications

Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer

(2016) Masaaki Miyo et al.   Scientific Reports

Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase

(2016) Kosuke Toda et al.   NEOPLASIA

Amino Acid Transporters in Cancer and Their Relevance to "Glutamine Addiction": Novel Targets for the Design of a New Class of Anticancer Drugs

(2015) Y. D. Bhutia et al.   CANCER RESEARCH

Metabolic Dependencies in RAS-Driven Cancers

(2015) A. C. Kimmelman   CLINICAL CANCER RESEARCH

Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

(2015) Mohamed Hassanein et al.   INTERNATIONAL JOURNAL OF CANCER

Relationship Between 18F-FDG PET/CT Scans and KRAS Mutations in Metastatic Colorectal Cancer

(2015) K. Kawada et al.   JOURNAL OF NUCLEAR MEDICINE

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

(2015) Qian Wang et al.   JOURNAL OF PATHOLOGY

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer

(2015) M van Geldermalsen et al.   ONCOGENE

Expression of Amino Acid Transporters (LAT1 and ASCT2) in Patients with Stage III/IV Laryngeal Squamous Cell Carcinoma

(2015) Osamu Nikkuni et al.   PATHOLOGY & ONCOLOGY RESEARCH

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

(2015) J. Yun et al.   SCIENCE

High expression of Solute Carrier Family 1, member 5 (SLC1A5) is associated with poor prognosis in clear-cell renal cell carcinoma

(2015) Yidong Liu et al.   Scientific Reports

Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5)

(2014) Mariafrancesca Scalise et al.   AMINO ACIDS

ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer

(2014) K Shimizu et al.   BRITISH JOURNAL OF CANCER

Prognostic significance of amino-acid transporter expression (LAT1, ASCT2 and xCT) in surgically resected tongue cancer

(2014) M Toyoda et al.   BRITISH JOURNAL OF CANCER

Regulation of 18F-FDG Accumulation in Colorectal Cancer Cells with Mutated KRAS

(2014) M. Iwamoto et al.   JOURNAL OF NUCLEAR MEDICINE

ATF4 and N-Myc coordinate glutamine metabolism inMYCN-amplified neuroblastoma cells through ASCT2 activation

(2014) Ping Ren et al.   JOURNAL OF PATHOLOGY

KRAS: feeding pancreatic cancer proliferation

(2014) Kirsten L. Bryant et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Relationship between 18F-Fluorodeoxyglucose Accumulation and KRAS/BRAF Mutations in Colorectal Cancer

(2012) K. Kawada et al.   CLINICAL CANCER RESEARCH

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

(2012) Sandra Misale et al.   NATURE

Glutamine addiction: a new therapeutic target in cancer

(2010) David R. Wise et al.   TRENDS IN BIOCHEMICAL SCIENCES

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

(2009) R J DeBerardinis et al.   ONCOGENE

Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

(2009) J. Yun et al.   SCIENCE

Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer

(2008) Carsten Bokemeyer et al.   JOURNAL OF CLINICAL ONCOLOGY

K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer

(2008) Christos S. Karapetis et al.   NEW ENGLAND JOURNAL OF MEDICINE