Optimization of Polyplex Formation between DNA Oligonucleotide and Poly(ʟ-Lysine): Experimental Study and Modeling Approach

Recent Advances in Nucleic Acid-Based Delivery: From Bench to Clinical Trials in Genetic Diseases

(2016) Cláudia Oliveira et al.   Journal of Biomedical Nanotechnology

Experimental design, modeling and optimization of polyplex formation between DNA oligonucleotides and branched polyethylenimine

(2015) Lilia Clima et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chemistry specificity of DNA–polycation complex salt response: a simulation study of DNA, polylysine and polyethyleneimine

(2015) Hanne S. Antila et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The Antimicrobial Mechanism of Action of Epsilon-Poly-l-Lysine

(2014) Morten Hyldgaard et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Application of response surface methodology and artificial neural network methods in modelling and optimization of biosorption process

(2014) Anna Witek-Krowiak et al.   BIORESOURCE TECHNOLOGY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Optimization of recombinant hexaoligochitin-producing chitinase production with response surface methodology

(2013) Chao-Lin Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cost effective production of pullulan from agri-industrial residues using response surface methodology

(2013) Ananya Mehta et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Innovative use of Mucuna monosperma (Wight) callus cultures for continuous production of melanin by using statistically optimized biotransformation medium

(2013) Shrirang Inamdar et al.   JOURNAL OF BIOTECHNOLOGY

Gene therapy clinical trials worldwide to 2012 - an update

(2013) Samantha L. Ginn et al.   JOURNAL OF GENE MEDICINE

Independent versus Cooperative Binding in Polyethylenimine–DNA and Poly(l-lysine)–DNA Polyplexes

(2013) Tiia-Maaria Ketola et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

(2012) Julien Nicolas et al.   CHEMICAL SOCIETY REVIEWS

Understanding the Effect of Polylysine Architecture on DNA Binding Using Molecular Dynamics Simulations

(2011) Robert M. Elder et al.   BIOMACROMOLECULES

The effect of environmental pH on polymeric transfection efficiency

(2011) Han Chang Kang et al.   BIOMATERIALS

Development of pH-sensitive tamarind seed polysaccharide–alginate composite beads for controlled diclofenac sodium delivery using response surface methodology

(2011) Amit Kumar Nayak et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin

(2011) Zhenyu Wang et al.   JOURNAL OF BIOTECHNOLOGY

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS

Structure, Dynamics, and Energetics of siRNA−Cationic Vector Complexation: A Molecular Dynamics Study

(2010) Defang Ouyang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Molecular Dynamics Simulations of DNA-Polycation Complex Formation

(2009) Jesse Ziebarth et al.   BIOPHYSICAL JOURNAL

Non-viral gene delivery carrier and its three-dimensional transfection system

(2009) Cai-Xia He et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

Response surface methodology (RSM) as a tool for optimization in analytical chemistry

(2008) Marcos Almeida Bezerra et al.   TALANTA