Hypoxia Mediates Differential Response to Anti-EGFR Therapy in HNSCC Cells

Cetuximab sensitivity of head and neck squamous cell carcinoma xenografts is associated with treatment-induced reduction in EGFR, pEGFR, and pSrc

(2017) Adam Jedlinski et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

The hypoxic microenvironment: A determinant of cancer stem cell evolution

(2016) Amancio Carnero et al.   BIOESSAYS

Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma

(2016) Aparna Jayachandran et al.   Journal of Hematology & Oncology

The relationship between EMT, CD44high/EGFRlowphenotype, and treatment response in head and neck cancer cell lines

(2016) Ann-Charlotte Johansson et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Correction: Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways

(2016) David W. Greening et al.   Oncotarget

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

(2016) Shih-Han Kao et al.   Journal of Clinical Medicine

The Epithelial-Mesenchymal Transition and Cancer Stem Cells: Functional and Mechanistic Links

(2015) Xiangqiang Liu et al.   CURRENT PHARMACEUTICAL DESIGN

Roles of hypoxia, stem cells and epithelial-mesenchymal transition in the spread and treatment resistance of head and neck cancer

(2015) Luke Gammon et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

The expression pattern of PFKFB3 enzyme distinguishes between induced-pluripotent stem cells and cancer stem cells

(2015) Artur Cieślar-Pobuda et al.   Oncotarget

Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

(2015) Sandra Schmitz et al.   Oncotarget

Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions

(2015) Oihana Iriondo et al.   Oncotarget

Clinical implications of hypoxia biomarker expression in head and neck squamous cell carcinoma: a systematic review

(2015) Justin E. Swartz et al.   Cancer Medicine

Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

(2015) Yu-Chin Lin et al.   NEOPLASIA

Cell adhesion molecules and their relation to (cancer) cell stemness

(2014) Ensieh Farahani et al.   CARCINOGENESIS

Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

(2014) V. Zecchini et al.   EMBO JOURNAL

YAP1 is a potential biomarker for cetuximab resistance in head and neck cancer

(2014) Fredrik Jerhammar et al.   ORAL ONCOLOGY

Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors

(2013) M Ahmadi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance

(2013) L Chang et al.   Cell Death & Disease

EGFR status and EGFR ligand expression influence the treatment response of head and neck cancer cell lines

(2012) Adam Jedlinski et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

A CD44high/EGFRlow Subpopulation within Head and Neck Cancer Cell Lines Shows an Epithelial-Mesenchymal Transition Phenotype and Resistance to Treatment

(2012) Linnea La Fleur et al.   PLoS One

The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure

(2012) Steven B. Chinn et al.   Frontiers in Endocrinology

Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma

(2011) Fredrik Jerhammar et al.   CANCER BIOLOGY & THERAPY

Cancer Stem Cells in Squamous Cell Carcinoma Switch between Two Distinct Phenotypes That Are Preferentially Migratory or Proliferative

(2011) A. Biddle et al.   CANCER RESEARCH

Evidence for Epithelial-Mesenchymal Transition in Cancer Stem Cells of Head and Neck Squamous Cell Carcinoma

(2011) Chao Chen et al.   PLoS One

Epithelial–mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells

(2011) Carmen Holz et al.   RADIOTHERAPY AND ONCOLOGY

E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells

(2011) Jan Theys et al.   RADIOTHERAPY AND ONCOLOGY

Revisiting the TCA cycle: signaling to tumor formation

(2011) Nuno Raimundo et al.   TRENDS IN MOLECULAR MEDICINE

Epithelial-Mesenchymal Transition in tumor microenvironment

(2011) Yingying Jing et al.   Cell and Bioscience

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Targeting breast cancer stem cells

(2009) Max S. Wicha   BREAST

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer

(2009) K Lundgren et al.   BRITISH JOURNAL OF CANCER

Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

(2009) Nawneet K. Kurrey et al.   STEM CELLS

Requirement of hypoxia-inducible factor-1  down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab

(2008) X. Li et al.   MOLECULAR CANCER THERAPEUTICS