Journal
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Volume 61, Issue -, Pages 7-12Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2017.04.003
Keywords
Mediterranean spotted fever; Rickettsia israelensis; Israeli spotted fever
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Mediterranean spotted fever (MSF) is endemic in Italy, where Rickettsia conorii subsp. conorii was thought to be the only pathogenic rickettsia and Rhipicephalus sanguineus the vector and main reservoir. R. conorii subsp. israelensis, which belongs to the R. conorii complex, is the agent of Israeli spotted fever (ISF); apart from Israel, it has also been found in Italy (Sicily and Sardinia) and in different regions of Portugal. We describe here two severe cases of ISF which occurred in otherwise healthy Italian adults. Their characteristics are analyzed and discussed in the light of other 91 cases found through a systematic review of international literature. (C) 2017 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
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