Review
Endocrinology & Metabolism
Juan Juan, Yiying Sun, Yumei Wei, Shuang Wang, Geng Song, Jie Yan, Pengxiang Zhou, Huixia Yang
Summary: A systematic review and meta-analysis found that women diagnosed with gestational diabetes mellitus (GDM) according to the International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria have a higher risk of developing type 2 diabetes mellitus (T2DM) and prediabetes. The risk of T2DM in GDM women increases with longer follow-up duration.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Anam Shakil Rai, Line Sletner, Anne Karen Jenum, Nina Cecilie Overby, Signe Nilssen Stafne, Tove Lekva, Are Hugo Pripp, Linda Reme Sagedal
Summary: This study assessed the prevalence of gestational diabetes using three diagnostic criteria and evaluated the predictive accuracy of commonly used risk factors. The results showed that the prevalence of GDM was higher for non-European women under the 2013WHO criteria. Clinical risk factors like age and BMI were not effective in predicting GDM without a high percentage of women undergoing OGTT testing.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Endocrinology & Metabolism
Maryam Saeedi, Yang Cao, Helena Fadl, Hanne Gustafson, David Simmons
Summary: The study found that implementing the IADPSG criteria resulted in a 75% increase in gestational diabetes prevalence compared to old GDM criteria, but also led to more homogeneity. More research is needed to evaluate the benefits, harms, psychological effects, and health costs of implementing the IADPSG criteria.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
B. Bhavadharini, R. M. Anjana, M. Deepa, R. Pradeepa, R. Uma, P. Saravanan, V Mohan
Summary: The study aimed to examine the association between abnormal glucose values and FPG levels with pregnancy outcomes. Results showed that the risk for poor pregnancy outcomes increases with higher abnormal values in the OGTT or FPG > 92mg/dl. Risk of cesarean section and large for gestation age was significantly higher in women with abnormal glucose values or high FPG levels.
ACTA DIABETOLOGICA
(2022)
Article
Multidisciplinary Sciences
Penny Lam, Brendan J. Mein, Ronald J. Benzie, John T. Ormerod, Kristy P. Robledo, Emily J. Hibbert, Ralph K. Nanan
Summary: This study analyzed the effects of maternal diabetes mellitus and body mass index on central and peripheral fat accrual in large for gestational age offspring. The results showed that diabetes mellitus was associated with increased abdominal and mid-thigh fat accumulation in fetuses, independent of BMI.
Article
Multidisciplinary Sciences
Qing-Xiang Zheng, Hai-Wei Wang, Xiu-Min Jiang, Yan Lin, Gui-Hua Liu, Mian Pan, Li Ge, Xiao-Qian Chen, Jing-Ling Wu, Xiao-Yun Zhang, Yu-Qing Pan, Hong-Gu He
Summary: This study aimed to determine the ranges of gestational weight gain (GWG) in Chinese women with gestational diabetes mellitus (GDM) and investigate the associations between prepregnancy body mass index (BMI), GWG, and maternal-infant adverse outcomes. The findings revealed that the ranges of GWG in Chinese women with GDM were different from the National Academy of Medicine's recommendation, and GDM women with high prepregnancy BMI and excessive GWG were associated with higher risks of adverse outcomes for both the mother and the infant.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Anais Serati, Chiara Novielli, Gaia Maria Anelli, Maria Mandalari, Francesca Parisi, Irene Cetin, Renata Paleari, Chiara Mando
Summary: Maternal obesity and gestational diabetes mellitus (GDM) are associated with adverse maternal and foetal outcomes, and involve epigenetic alterations contributing to the pathogenesis of metabolic diseases. This pilot study analyzed plasma microRNAs in obese pregnant women with/without GDM, revealing differentially expressed microRNAs related to oxidative stress, inflammation, nutrients, and hormones metabolism. These findings provide insight into the complex epigenetic network regulating metabolic pathways in MO and GDM, but further investigations are needed.
Article
Endocrinology & Metabolism
Evelyne M. Aubry, Luigi Raio, Stephan Oelhafen
Summary: The introduction of the IADPSG criteria for screening GDM significantly increased the prevalence of GDM, however, it did not substantially improve GDM-related events for women without risk factors. Instead, it reduced the risks for newborns large for gestational age (LGA), neonatal hypoglycemia, and preterm birth.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Chen Zhang, Lilian Bai, Kuan Sun, Guolian Ding, Xinmei Liu, Yanting Wu, Hefeng Huang
Summary: This study examines the combined effects of FT4 and TG on the prevalence of GDM in early pregnancy and finds that low TG levels are an important mediator in reducing the risk of GDM.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Jiangheng Li, Jingli Yan, Linghua Ma, Yongquan Huang, Maoling Zhu, Wu Jiang
Summary: The study found that the prevalence of gestational diabetes mellitus (GDM) and advanced maternal age (AMA, >= 35 years) is increasing worldwide. This study evaluated the risks of pregnancy outcomes among younger and older women with GDM and analyzed the epidemiological interaction between GDM and AMA.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Microbiology
Stephanie Dias, Carmen Pheiffer, Sumaiya Adam
Summary: Gestational diabetes mellitus (GDM) is associated with adverse maternal and neonatal outcomes and may be influenced by alterations in the maternal microbiome. Further research and clinical trials are necessary to fully understand and utilize the therapeutic potential of the maternal microbiome.
Article
Endocrinology & Metabolism
Yu Liu, Alan Kuang, James R. Bain, Michael J. Muehlbauer, Olga R. Ilkayeva, Lynn P. Lowe, Boyd E. Metzger, Christopher B. Newgard, Denise M. Scholtens, William L. Lowe
Summary: This study analyzed metabolites in women at approximately 28 weeks' gestation and found associations with GDM and postpartum disorders of glucose metabolism. Some metabolites were identified as mediating the relationship between GDM and postpartum disorders, highlighting the pathophysiological transition from GDM to a postpartum disorder of glucose metabolism.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Marie Parfaite Uwimana Muhuza, Lixia Zhang, Qi Wu, Lu Qi, Danqing Chen, Zhaoxia Liang
Summary: This study investigated the association between HbA1c levels and adverse outcomes in women with gestational diabetes mellitus (GDM), considering maternal age, pre-pregnancy BMI, and gestational weight gain (GWG). The results showed that HbA1c was significantly associated with macrosomia, pregnancy-induced hypertension (PIH), preterm birth, and primary Cesarean section. The associations varied with maternal age, pre-pregnancy BMI, and GWG.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Gergely A. Visolyi, Attila Kun, Orsolya Szalai, Mark M. Svebis, Beatrix A. Domjan, Laszlo Zsirai, Adam G. Tabak
Summary: Untreated 'mild' gestational diabetes mellitus (GDM) in pregnant women had worse pregnancy outcomes compared to normal glucose tolerant women, but these differences were explained by pre-pregnancy BMI after adjustment.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Endocrinology & Metabolism
Anne H. Y. Chu, Wen Lun Yuan, See Ling Loy, Shu E. Soh, Jonathan Y. Bernard, Mya-Thway Tint, Sarah S. T. Ho-Lim, Huecin Goh, Adaikalavan Ramasamy, Mukkesh Kumar, Claire Goh, Li Ting Ang, Lynette Pei-Chi Shek, Yap Seng Chong, Kok Hian Tan, Lin Lin Su, Arijit Biswas, Fabian Yap, Yung Seng Lee, Claudia Chi, Keith M. Godfrey, Johan Gunnar Eriksson, Shiao-Yng Chan
Summary: The study found an association between height and gestational diabetes (GDM) diagnosis and complications during pregnancy, with shorter women more likely to be diagnosed with GDM, and GDM being more strongly associated with complications such as preterm delivery and higher birthweight among taller women.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Pediatrics
Ali Ovayolu, Gamze Ovayolu, Erbil Karaman, Tuncay Yuce, Murat A. Ozek, Vugar A. Turksoy
CONGENITAL ANOMALIES
(2020)
Article
Obstetrics & Gynecology
Deniz Karcaaltincaba, Murat Aykut Ozek, Nagehan Ocal, Pinar Calis, Melis Altug Inan, Merih Bayram
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2020)
Article
Pathology
Pinar Calis, Merve Seymen, Yagmur Soykan, Kevser Delen, Bahriye Sirav Aral, Gulnur Take Kaplanoglu, Deniz Karcaaltincaba
Summary: The study showed that prenatal exposure to smart phone radiation can lead to a decrease in ovarian reserve in offspring, while supplementation of omega-3 during pregnancy may help reduce the potential risk of premature ovarian failure.
FETAL AND PEDIATRIC PATHOLOGY
(2021)
Article
Obstetrics & Gynecology
Ali Ovayolu, Vugar Ali Turksoy, Gamze Ovayolu, Murat Aykut Ozek, Ilkay Dogan, Erbil Karaman
Summary: This study investigated the concentrations of presepsin and other inflammatory markers in preeclampsia and healthy pregnant women. The results showed that lower concentrations of interleukin-6/presepsin and higher concentrations of pentraxin-3 were associated with the development of preeclampsia.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ali Ovayolu, Gamze Ovayolu, Tuncay Yuce, Murat Aykut Ozek, Ilkay Dogan, Nuray Bostancieri
JOURNAL OF PERINATAL MEDICINE
(2020)
Letter
Obstetrics & Gynecology
Deniz Karcaaltincaba, Murat Aykut Ozek, Nagehan Ocal, Pinar Calis, Melis Altug Inan, Merih Bayram
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Article
Health Care Sciences & Services
Pinar Calis, Deniz Karcaaltincaba, Gizem Isik, Firat Buyuktaskin, Merih Bayram, Onur Karabacak
EASTERN MEDITERRANEAN HEALTH JOURNAL
(2020)
Article
Surgery
Omer Faruk Akcay, Haci Hasan Yeter, Deniz Karcaaltincaba, Merih Bayram, Galip Guz, Yasemin Erten
Summary: The study investigated obstetric and graft outcomes in 29 pregnancies of 18 female kidney transplant recipients. It found that pregnancy after kidney transplantation is associated with high rates of maternal and fetal complications, and may lead to sustained decline of graft function compared to recipients without pregnancy history.
CLINICAL TRANSPLANTATION
(2021)
Article
Obstetrics & Gynecology
Ezgi Turgut, Gokce Turan, Halis Ozdemir, Fatma Aktulum, Merih Bayram, Deniz Karcaaltincaba
Summary: This retrospective study analyzed the changes in fetal cardiac morphology and geometry in gestational diabetes mellitus (GDM) pregnancies at 20-22 weeks of gestation. The findings indicate significant differences in cardiac structural measurements between the GDM A1 and GDM A2 groups compared to the control group, suggesting that GDM can cause early changes in fetal cardiac structure.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ezgi Turgut, Halis Ozdemir, Gokce Turan, Merih Bayram, Deniz Karcaaltincaba
Summary: The study found that a higher percentage of FGR fetuses required neonatal intensive care unit compared to SGA fetuses. FGR fetuses demonstrated lower left spherical index, decreased left ventricular wall thickness, increased right/left ventricular wall ratio, lower tricuspid/mitral valve ratio, lower mitral annular plane systolic excursion value, and higher myocardial performance index. These findings suggest cardiac structural and functional changes in FGR cases, with both systolic and diastolic dysfunctions detected in the left heart.
JOURNAL OF PERINATAL MEDICINE
(2022)
Article
Acoustics
Ezgi Turgut, Halis Ozdemir, Gokce Turan, Deniz Karcaaltincaba, Merih Bayram
Summary: This study classified congenital heart defects (CHDs) based on cerebral blood flow oxygenation and assessed their impact on fetal brain structure. The results showed that brain structure changes were more prominent in groups with low cerebral oxygenation, particularly in the single ventricle (SV) and transposition of great arteries (TGA) cases.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Obstetrics & Gynecology
Deniz Karcaaltincaba, Mehmet Emin Ozdogan, Ezgi Turgut, Halis Ozdemir, Gulten Tacoy, Gozde Inan
Summary: Successful pregnancy outcomes are possible in female heart transplant recipients of reproductive age with careful and close surveillance by a multidisciplinary team. Monitoring and care are essential for ensuring a healthy pregnancy and delivery.
CASE REPORTS IN PERINATAL MEDICINE
(2021)
Article
Anesthesiology
Berrin Gunaydin, Selin Bagcaz, Gozde Inan, Esin Tckin, Deniz Karcaaltmcaba
Summary: A parturient experienced acute parotitis complication during elective CS under spinal anaesthesia, with a history of similar complication after epidural anaesthesia.
TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
(2021)
Article
Medicine, General & Internal
Erkan Yurtcu, Deniz Karcaaltincaba, Hasan Huseyin Kazan, Halis Ozdemir, Meral Yirmibes Karaoguz, Pinar Calis, Gulsum Kayhan, Sezen Guntekin Ergun, Ferda Percin, Merih Bayram, Mustafa Necmi Ilhan, Gamze Bilgili, Tugrul Kaymak, Mehmet Ali Ergun
Summary: The study aimed to isolate fetal cells from endocervical samples and identify possible anomalies using specific antibodies. However, the success rate of the method was limited, and further improvements are needed for its applicability in clinics.
TURKISH JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Obstetrics & Gynecology
Ezgi Turgut, Gozde Inan, Dudu Berrin Gunaydin, Beyza Buyukgebiz, Sibel Konca, Deniz Karcaaltincaba, Merih Bayram
Summary: A study of 20 pregnant women who underwent renal transplant showed good perinatal outcomes despite complications such as hypertension and preeclampsia. Antenatal/peripartum follow-up and analgesia/anesthesia management of renal transplant recipients resulted in successful perinatal outcomes.
TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
