Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 31, Issue -, Pages 117-121Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2014.10.012
Keywords
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Funding
- National Institutes of Health National Center for Advancing Translational Sciences (NIH-NCATS) [UH2TR000491]
- National Science Foundation Major Research Instrumentation program (NSF/MRI) [CHE-1229341]
- Vanderbilt Institute of Chemical Biology
- Vanderbilt Institute for Integrative Biosystems Research and Education
- Vanderbilt College of Arts and Sciences
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1229341] Funding Source: National Science Foundation
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Contemporary strategies that concentrate on only one or a handful of molecular targets limits the utility of the information gained for diagnostic and predictive purposes. Recent advances in the sensitivity, speed, and precision of measurements obtained from ion mobility coupled to mass spectrometry (IM-MS) have accelerated the utility of IM-MS in untargeted, discovery-driven studies in biology. Perhaps most evident is the impact that such wide-scale discovery capabilities have yielded in the areas of systems, synthetic, and chemical biology, where the need for comprehensive, hypothesis-driving studies from multidimensional and unbiased data is required.
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