Induction of Cbl-dependent epidermal growth factor receptor degradation in Ling Zhi-8 suppressed lung cancer

Small Molecule T315 Promotes Casitas B-Lineage Lymphoma–Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation

(2016) Kuo-Yen Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ling Zhi-8 reduces lung cancer mobility and metastasis through disruption of focal adhesion and induction of MDM2-mediated Slug degradation

(2016) Tung-Yi Lin et al.   CANCER LETTERS

Preclinical Trials for Prevention of Tumor Progression of Hepatocellular Carcinoma by LZ-8 Targeting c-Met Dependent and Independent Pathways

(2015) Jia-Ru Wu et al.   PLoS One

Tid1-L Inhibits EGFR Signaling in Lung Adenocarcinoma by Enhancing EGFR Ubiquitinylation and Degradation

(2013) Chi-Yuan Chen et al.   CANCER RESEARCH

Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands

(2013) Lasse Henriksen et al.   PLoS One

EPS8 Inhibition Increases Cisplatin Sensitivity in Lung Cancer Cells

(2013) Lidija K. Gorsic et al.   PLoS One

Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes

(2013) Shih-Fen Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation

(2012) C-C Chang et al.   CELL DEATH AND DIFFERENTIATION

The road to resistance: EGFR mutation and cetuximab

(2012) Alberto Bardelli et al.   NATURE MEDICINE

GMI, an immunomodulatory protein fromGanoderma microsporum, induces autophagy in non-small cell lung cancer cells

(2011) I-Lun Hsin et al.   Autophagy

Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway

(2011) Chien-Ting Wu et al.   CARCINOGENESIS

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells

(2010) Y Gan et al.   ONCOGENE

Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells

(2008) Hsien-Yeh Hsu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Tale of Two Cbls: Interplay of c-Cbl and Cbl-b in Epidermal Growth Factor Receptor Downregulation

(2008) S. Pennock et al.   MOLECULAR AND CELLULAR BIOLOGY

Crystal structure of LZ-8 from the medicinal fungusGanoderma lucidium

(2008) Liang Huang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS