Neuromedin U alters bioenergetics and expands the cancer stem cell phenotype in HER2-positive breast cancer

Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer

(2016) Yang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuromedin U: A Multifunctional Neuropeptide with Pleiotropic Roles

(2015) V. G. Martinez et al.   CLINICAL CHEMISTRY

Versatile functions for IL-6 in metabolism and cancer

(2015) Jan Mauer et al.   TRENDS IN IMMUNOLOGY

Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors

(2014) S. Rani et al.   CANCER RESEARCH

Hsp27 Regulates Epithelial Mesenchymal Transition, Metastasis, and Circulating Tumor Cells in Prostate Cancer

(2013) M. Shiota et al.   CANCER RESEARCH

Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

(2013) Christine L. Chaffer et al.   CELL

The Warburg effect version 2.0: Metabolic reprogramming of cancer stem cells

(2013) JAVIER MENENDEZ et al.   CELL CYCLE

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Energy metabolism plasticity enables stemness programs

(2012) Clifford D.L. Folmes et al.   Annals of the New York Academy of Sciences

Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population

(2012) Hasan Korkaya et al.   MOLECULAR CELL

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death

(2012) Nicholas A Graham et al.   Molecular Systems Biology

The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells

(2012) Kakajan Komurov et al.   Molecular Systems Biology

Overexpression of Pyruvate Dehydrogenase Kinase 3 Increases Drug Resistance and Early Recurrence in Colon Cancer

(2011) Chun-Wun Lu et al.   AMERICAN JOURNAL OF PATHOLOGY

Metabolic Flux and the Regulation of Mammalian Cell Growth

(2011) Jason W. Locasale et al.   Cell Metabolism

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

(2011) D. Iliopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer metabolism: The Warburg effect today

(2010) Leonardo M.R. Ferreira   EXPERIMENTAL AND MOLECULAR PATHOLOGY

TGF-  IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

(2010) Z. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

(2010) M. G. Vander Heiden et al.   SCIENCE

Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S

(2009) JD Mitchell et al.   BRITISH JOURNAL OF PHARMACOLOGY

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells

(2009) N J Sullivan et al.   ONCOGENE

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nmur1−/− mice are not protected from cutaneous inflammation

(2008) Susan J. Abbondanzo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

(2008) Chun-Wun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY