Article
Microbiology
Yue Sun, Zi-Lu Liu, Bo-Yang Hu, Qing-Jun Chen, Ai-Zhen Yang, Qiu-Ying Wang, Xiao-Feng Li, Jia-Yan Zhang, Guo-Qing Zhang, Yong-Chang Zhao
Summary: An extracellular laccase (GLL) was successfully purified from the litter-decomposing fungus Gymnopus luxurians, showing high specific activity, purification fold, thermostability, pH stability, and effective dye decolorization abilities.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Chao Duan, Feng-Hua Tian, Lan Yao, Jian-Hua Lv, Chuan-Wen Jia, Chang-Tian Li
Summary: In this study, the developmental transcriptomes of Sarcomyxa edulis were analyzed to uncover the molecular mechanisms underlying lignocellulose degradation. A co-expression network analysis revealed gene modules significantly associated with lignocellulose degradation, and key genes and transcription factor families involved in this process were identified. These findings provide important insights into the molecular genetic mechanisms of lignocellulose degradation in S. edulis.
SCIENTIFIC REPORTS
(2022)
Article
Biotechnology & Applied Microbiology
Alshaimaa M. M. Elsayed, Mohamed Mahmoud, Ghada S. A. Abdel Karim, Mohamed Abdelraof, Abdelmageed M. M. Othman
Summary: Two laccase isoenzymes (LacA and LacB) were isolated and purified from Trichoderma harzianum S7113. LacA had a molecular weight of 63 kDa, while LacB had a molecular weight of 48 kDa. Both isoenzymes exhibited optimum activity at 50℃, but at slightly different pH values. They also showed similar thermal and pH stability. LacA and LacB had high specific activity toward ABTS, with LacB having a lower K-m and V-max value than LacA. The catalytic activity of both isoenzymes was affected by various ions, and completely inhibited by sodium azide.
MICROBIAL CELL FACTORIES
(2023)
Article
Energy & Fuels
Ayesha Riffat, Zahid Anwar, Muddassar Zafar, Fareeha Nadeem, Tahir Mehmood
Summary: This study demonstrates the high yield of laccase production from the indigenous fungal strain Fomes fomentarius using corn stover as a substrate. The purified laccase showed optimal activity at pH 7 and 35-40 degrees C, and exhibited significant lignin degradation and decolorization properties.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Chemistry, Multidisciplinary
Yun-peng Jiang, Jun-li Cai, Jian-jun Pei, Qi Li, Lin-guo Zhao
Summary: The thermostable and organic solvent-tolerant bacterial laccase from Bacillus pumilus ARA has potential in decolorizing various industrial synthetic dyes. With optimal temperature and pH conditions, the enzyme activity significantly increased, showing promising applications in the future.
Article
Materials Science, Biomaterials
Adriany das Gracas Nascimento Amorim, Marta Sanchez-Paniagua, Taiane Maria de Oliveira, Ana Carolina Mafud, Durcilene Alves da Silva, Jose Roberto de Souza de Almeida Leite, Beatriz Lopez-Ruiz
Summary: This study demonstrated the immobilization of an enzyme on cashew gum nanoparticles for the development of an electrochemical biosensor. The enzyme-CG nanoparticles showed good particle size distribution and colloidal stability. The resulting amperometric biosensor exhibited fast response time, high sensitivity, wide linear range, and low detection limit.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Biotechnology & Applied Microbiology
Ahmed A. Hamed, Ahmed M. Abd-Elaziz, Manal M. E. Ghanem, Mohamed E. Elawady, Mohamed S. Abdel-Aziz
Summary: A laccase-producing fungus (MY3) was isolated from soil samples in Egypt, showing higher laccase production compared to other isolated fungi. It was identified as Curvularia lunata MY3 using the molecular technique 18SrRNA. The enzyme was purified using several chromatography techniques, and its properties, such as optimal temperature and pH, stability, and substrate specificity, were determined. The antimicrobial activity of the purified enzyme against pathogenic strains was also evaluated.
FOLIA MICROBIOLOGICA
(2023)
Article
Chemistry, Multidisciplinary
Cagatay M. Oral, Martina Ussia, Martin Pumera
Summary: In this study, enzyme-immobilized self-propelled zinc oxide microrobots were proposed to effectively remove antibiotics released into water bodies. The presence of laccase enzyme on the microrobot surfaces enhanced the removal of antibiotics via oxidation. This concept provides an environmentally friendly strategy for the removal of released antibiotics from water bodies.
Article
Cell Biology
Olga M. Demkiv, Galina Z. Gayda, Daniel Broda, Mykhailo V. Gonchar
Summary: This study obtained a highly purified laccase from a fungal source and demonstrated its potential applications in bioanalytics and bioremediation. Through screening of fungal strains, the optimal producer of laccase was identified and key characteristics of the enzyme were determined.
CELL BIOLOGY INTERNATIONAL
(2021)
Article
Chemistry, Physical
Sonal Chaudhary, Ajit Varma, Saurabh Jha, Sanjay K. S. Patel, Shalini Porwal
Summary: Bacterial laccase from Bhargavaea beijingensis was successfully amplified, transformed, and purified. The purified laccase showed optimum pH and temperature at 8.0 and 50 degrees C, respectively, and exhibited stable activity across a broad range of pH and temperature. The laccase demonstrated significant dye decolorization capability, particularly towards congo red.
Article
Biochemistry & Molecular Biology
Azam ElyasiGhahfarokhi, Saba Hashemi, Mina Saeedi, Mahnaz Khanavi, Mohammad Ali Faramarzi
Summary: This study describes an efficient method for purifying laccase (PaL) from Pistacia atlantica Desf. resin, achieving a high specific activity and purification fold. PaL showed stability and high affinity towards specific substrates, as well as significant growth inhibition effects on cancer cells in vitro.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Navleen Kaur Chopra, Sonica Sondhi
Summary: The laccase gene from Bacillus licheniformis NS2324 was cloned and expressed in E. coli, and its properties and activities were studied. The results showed that the recombinant laccase exhibited good tolerance and decolorization ability, making it suitable for eco-friendly and cost-effective dye decolorization in industrial applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Environmental Sciences
Jing Si, Yi Wu, Hong-Fei Ma, Yong-Jia Cao, Yi-Fei Sun, Bao-Kai Cui
Summary: This study discovered a new pH- and temperature-stable laccase, Galacc-F, from Ganoderma australe, with high activity, broad substrate specificity, and stability in industrial processes. The enzyme was successfully immobilized onto Fe3O4@Chitosan composite nanoparticles using glutaraldehyde as a crosslinker, showing high tolerance to various conditions.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2021)
Article
Microbiology
Benedicte Z. E. Aka, Theodore N. Djeni, Hubert K. Konan, Cristina A. Semeniuc, Ancuta M. Rotar, Ramona Suharoschi, Marcellin K. Dje
Summary: In this study, Trametes polyzona strain with high laccase activity was isolated and found to have promising application in POME treatment. Under specific culture conditions, this strain can significantly reduce COD, suspended solids, total solids, and total phenolics in POME.
CURRENT MICROBIOLOGY
(2021)
Review
Food Science & Technology
Dilshad Begum M. Golgeri, Sikandar Mulla, Zabin K. Bagewadi, Swati Tyagi, Anyi Hu, Swati Sharma, Muhammad Bilal, Ram Naresh Bharagava, Luiz Fernando R. Ferreira, Dummi Mahadevan Gurumurthy, Ashok Kumar Nadda
Summary: Microbial enzymes, particularly carbohydrases, have gained significant attention due to their stability and potential applications in areas such as bioenergy, biofuel production, and biobleaching. Isolating novel microbes from harsh environments has become a major focus for scientists. This review highlights the importance and properties of carbohydrases, specifically amylase, cellulase, laccase, pectinase, and xylanase, and explores their applications, production optimization, molecular approaches for enhanced production, and future biotechnological perspectives. Green and sustainable catalytic conversion strategies using enzyme nanoparticles are also discussed.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biotechnology & Applied Microbiology
Yuan Yuan, Fang Wu, Jing Si, Yi-Fan Zhao, Yu-Cheng Dai
Article
Biochemistry & Molecular Biology
Jing Si, Ge Meng, Yi Wu, Hong-Fei Ma, Bao-Kai Cui, Yu-Cheng Dai
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2019)
Article
Microbiology
Lin Zhu, Jie Song, Jun-Liang Zhou, Jing Si, Bao-Kai Cui
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Mycology
L. L. Shen, M. Wang, J. L. Zhou, J. H. Xing, B. K. Cui, Y. C. Dai
Article
Mycology
Jia-Hui Xing, Jun-Liang Zhou, Bao-Kai Cui
MYCOLOGICAL PROGRESS
(2020)
Article
Mycology
Y. -F. Sun, D. H. Costa-Rezende, J. -H. Xing, J. -L. Zhou, B. Zhang, T. B. Gibertoni, G. Gates, M. Glen, Y. -C. Dai, B. -K. Cui
Article
Microbiology
Shun Liu, Lu-Lu Shen, Yan Wang, Tai-Min Xu, Genevieve Gates, Bao-Kai Cui
Summary: Cyanosporus is a cosmopolitan brown-rot fungal genus characterized by blue-tinted basidiocarps. Recent studies have identified five new species within this genus and transferred fifteen species from another complex. Phylogenetic analyses were conducted using various genetic markers to support these taxonomic changes.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Jing Si, Hongfei Ma, Yongjia Cao, Baokai Cui, Yucheng Dai
Summary: This study introduces a valuable laccase, ThLacc-S, which efficiently metabolizes endocrine disrupting chemicals and has high specific activity. The enzyme maintains stability in a wide temperature range and pH range, making it a promising green catalyst for various biotechnological and industrial applications.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Chang-Ge Song, Yuan-Yuan Chen, Shun Liu, Tai-Min Xu, Xiao-Lan He, Di Wang, Bao-Kai Cui
Summary: In this study, phylogenetic and taxonomic analyses of Phellodon from China were conducted using both single and multi-gene analysis. Three new species were discovered. This study provides a foundation for future phylogenetic studies of the genus.
Article
Mycology
Shun Liu, Yuan-Yuan Chen, Yi-Fei Sun, Xiao-Lan He, Chang-Ge Song, Jing Si, Dong-Mei Liu, Genevieve Gates, Bao-Kai Cui
Summary: Brown-rot fungi are important for forest ecosystems as they degrade wood cellulose and hemicellulose, and contribute to nutrient cycling. Recent studies have shown that the ability to produce brown rot has evolved independently multiple times. This study focuses on the classification and phylogenetic relationships of brown-rot fungi within the Polyporales, based on DNA sequences from various loci. The study proposes new families, genera, species, and combinations, and provides illustrations and descriptions for the new species.
Article
Microbiology
Chang-Ge Song, Yi-Fei Sun, Shun Liu, Yuan-Yuan Chen, Bao-Kai Cui
Summary: In this study, four new species of the Phellodon genus, namely P. caesius, P. henanensis, P. concentricus, and P. subgriseofuscus, were described from China based on morphological characters and molecular evidence. Phylogenetic analyses were conducted using the ITS + nLSU gene regions and the combined sequence dataset of ITS + nLSU + nSSU + RPB1 + RPB2 gene regions. Illustrated descriptions and ecological habits of the newly described species are provided.
Article
Microbiology
Xing Ji, Yi-Fei Sun, Dong-Mei Wu, Neng Gao, Bao-Kai Cui
Summary: In this study, phylogenetic analyses were conducted on Perenniporia species and related genera using DNA sequences of multiple loci. It was found that the genus Perenniporia is polyphyletic. Based on morphology and phylogeny, 15 new genera were proposed, 2 new species were described, and 37 new combinations were proposed. Illustrated descriptions of the new species were provided, along with identification keys to Perenniporia and its related genera.
Article
Microbiology
Hao Wang, Jin-Xin Ma, Dong-Mei Wu, Neng Gao, Jing Si, Bao-Kai Cui
Summary: This study investigated the bioactive components and antioxidant activities of various species of Sanghuangporus fungi. The results showed that the antioxidant capacity of Sanghuangporus is closely related to the contents of flavonoid and ascorbic acid, followed by polyphenol and triterpenoid, and finally, polysaccharide. These findings provide important resources and guidance for the separation, purification, and development of bioactive agents from wild Sanghuangporus species, as well as the optimization of their artificial cultivation conditions.
Article
Mycology
Sergei Polme, Kessy Abarenkov, R. Henrik Nilsson, Bjorn D. Lindahl, Karina Engelbrecht Clemmensen, Havard Kauserud, Nhu Nguyen, Rasmus Kjoller, Scott T. Bates, Petr Baldrian, Tobias Guldberg Froslev, Kristjan Adojaan, Alfredo Vizzini, Ave Suija, Donald Pfister, Hans-Otto Baral, Helle Jarv, Hugo Madrid, Jenni Norden, Jian-Kui Liu, Julia Pawlowska, Kadri Poldmaa, Kadri Partel, Kadri Runnel, Karen Hansen, Karl-Henrik Larsson, Kevin David Hyde, Marcelo Sandoval-Denis, Matthew E. Smith, Merje Toome-Heller, Nalin N. Wijayawardene, Nelson Menolli, Nicole K. Reynolds, Rein Drenkhan, Sajeewa S. N. Maharachchikumbura, Tatiana B. Gibertoni, Thomas Laessoe, William Davis, Yuri Tokarev, Adriana Corrales, Adriene Mayra Soares, Ahto Agan, Alexandre Reis Machado, Andres Arguelles-Moyao, Andrew Detheridge, Angelina de Meiras-Ottoni, Annemieke Verbeken, Arun Kumar Dutta, Bao-Kai Cui, C. K. Pradeep, Cesar Marin, Daniel Stanton, Daniyal Gohar, Dhanushka N. Wanasinghe, Eveli Otsing, Farzad Aslani, Gareth W. Griffith, Thorsten H. Lumbsch, Hans-Peter Grossart, Hossein Masigol, Ina Timling, Inga Hiiesalu, Jane Oja, John Y. Kupagme, Jozsef Geml, Julieta Alvarez-Manjarrez, Kai Ilves, Kaire Loit, Kalev Adamson, Kazuhide Nara, Kati Kungas, Keilor Rojas-Jimenez, Kriss Bitenieks, Laszlo Irinyi, Laszlo Laszlo Nagy, Liina Soonvald, Li-Wei Zhou, Lysett Wagner, M. Catherine Aime, Maarja opik, Maria Isabel Mujica, Martin Metsoja, Martin Ryberg, Martti Vasar, Masao Murata, Matthew P. Nelsen, Michelle Cleary, Milan C. Samarakoon, Mingkwan Doilom, Mohammad Bahram, Niloufar Hagh-Doust, Olesya Dulya, Peter Johnston, Petr Kohout, Qian Chen, Qing Tian, Rajasree Nandi, Rasekh Amiri, Rekhani Hansika Perera, Renata dos Santos Chikowski, Renato L. Mendes-Alvarenga, Roberto Garibay-Orijel, Robin Gielen, Rungtiwa Phookamsak, Ruvishika S. Jayawardena, Saleh Rahimlou, Samantha C. Karunarathna, Saowaluck Tibpromma, Shawn P. Brown, Siim-Kaarel Sepp, Sunil Mundra, Zhu-Hua Luo, Tanay Bose, Tanel Vahter, Tarquin Netherway, Teng Yang, Tom May, Torda Varga, Wei Li, Victor Rafael Matos Coimbra, Virton Rodrigo Targino de Oliveira, Vitor Xavier de Lima, Vladimir S. Mikryukov, Yongzhong Lu, Yosuke Matsuda, Yumiko Miyamoto, Urmas Koljalg, Leho Tedersoo
Summary: The article introduces a database FungalTraits to facilitate functional assignments and ecological interpretation of fungi, discussing the challenges between molecular identification of fungal diversity and knowledge of functional traits. Through the involvement of expert knowledge and tools, researchers reannotated a large number of fungal and Stramenopila genera, summarizing them into 17 lifestyle-related traits suitable for environmental studies.
Article
Mycology
Hai-Sheng Yuan, Xu Lu, Yu-Cheng Dai, Kevin D. Hyde, Yu-He Kan, Ivana Kusan, Shuang-Hui He, Ning-Guo Liu, V. Venkateswara Sarma, Chang-Lin Zhao, Bao-Kai Cui, Nousheen Yousaf, Guangyu Sun, Shu-Yan Liu, Fang Wu, Chuan-Gen Lin, Monika C. Dayarathne, Tatiana Baptista Gibertoni, Lucas B. Conceicao, Roberto Garibay-Orijel, Margarita Villegas-Rios, Rodolfo Salas-Lizana, Tie-Zheng Wei, Jun-Zhi Qiu, Ze-Fen Yu, Rungtiwa Phookamsak, Ming Zeng, Soumitra Paloi, Dan-Feng Bao, Pranami D. Abeywickrama, De-Ping Wei, Jing Yang, Ishara S. Manawasinghe, Dulanjalee Harishchandra, Rashika S. Brahmanage, Nimali I. de Silva, Danushka S. Tennakoon, Anuruddha Karunarathna, Yusufjon Gafforov, Dhandevi Pem, Sheng-Nan Zhang, Andre L. C. M. de Azevedo Santiago, Jadson Diogo Pereira Bezerra, Balint Dima, Krishnendu Acharya, Julieta Alvarez-Manjarrez, Ali H. Bahkali, Vinod K. Bhatt, Tor Erik Brandrud, Timur S. Bulgakov, E. Camporesi, Ting Cao, Yu-Xi Chen, Yuan-Yuan Chen, Bandarupalli Devadatha, Abdallah M. Elgorban, Long-Fei Fan, Xing Du, Liu Gao, Camila Melo Goncalves, Luis F. P. Gusmao, Naruemon Huanraluek, Margita Jadan, Ruvishika S. Jayawardena, Abdul Nasir Khalid, Ewald Langer, Diogo X. Lima, Nelson Correia de Lima-Junior, Carla Rejane Sousa de Lira, Jian-Kui (Jack) Liu, Shun Liu, Saisamorn Lumyong, Zong-Long Luo, Neven Matocec, M. Niranjan, Jose Ribamar Costa Oliveira-Filho, Viktor Papp, Eduardo Perez-Pazos, Alan J. L. Phillips, Peng-Lei Qiu, Yihua Ren, Rafael F. Castaneda Ruiz, Kamal C. Semwal, Karl Soop, Carlos A. F. de Souza, Cristina Maria Souza-Motta, Li-Hua Sun, Meng-Le Xie, Yi-Jian Yao, Qi Zhao, Li-Wei Zhou
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)