Article
Biotechnology & Applied Microbiology
Thiago de Sousa Fonseca, Ulisses Marcondes Freire de Oliveira, Maria da Conceicao Ferreira de Oliveira, Telma Leda Gomes de Lemos, Marcos Reinaldo da Silva, Nathalia Saraiva Rios, Luciana Rocha Barros Goncalves, Marcos Carlos de Mattos
Summary: The study investigated the immobilization of Amano lipase AK from P. fluorescens on different chitosan-containing supports, with lower molecular weight chitosan and chitosan lower molecular weight/sodium alginate showing the highest immobilization yields and activity results. In the kinetic resolution process, the most efficient derivatives were lipase immobilized on chitosan average molecular weight and chitosan low molecular weight/sodium alginate, yielding high enantiomeric excess and conversion rates for the synthesis of a drug used in Parkinson's disease treatment.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Energy & Fuels
Ana Carolina Lima, Khadidja Hachemane, Antonio E. Ribeiro, Ana Queiroz, Maria Carolina Sergi Gomes, Paulo Brito
Summary: Ionic liquid choline hydroxide (ChOH) was successfully applied as a catalyst for the transesterification reaction of triacylglycerols present in sunflower oil with methanol. The experimental results showed that a high ester yield can be achieved in a short reaction time under specific conditions. Kinetic modeling study indicated that a first-order model is the best fit for the reaction.
Article
Engineering, Environmental
Wellington Arthur, Danie Diedericks, Gerhardt Coetzee, Eugene Van Rensburg, F. Johann Gorgens
Summary: By recycling enzyme-containing supernatant or whole fermentation broth, significant enzyme savings can be achieved in the simultaneous saccharification and fermentation process of paper waste sludge, leading to up to 23% savings on the overall enzyme loading and an increase in ethanol concentration. This opens up the possibility of significant improvements in the economic viability of ethanol production from lignocellulosic substrates.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Juan Carlos Quintero-Diaz, Diego F. Mendoza, Claudio Avignone-Rossa
Summary: In this study, a kinetic model of acetone-butanol-ethanol (ABE) fermentation based on enzyme kinetics expressions was proposed. The model takes into account the effect of the co-substrate NADH as a modulating factor of cellular metabolism. The simulations obtained with the model showed a good fit to experimental data, surpassing previous models. The introduction of NADH in the model offers a basis for analyzing electrofermentation processes with Clostridium.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Priyanka V. Jawale, Bhalchandra M. Bhanage
Summary: The study focused on analyzing reaction kinetics and mechanism for synthesizing propyl benzoate in solvent-free conditions, immobilizing lipase on HPMC and PVA polymer blend, with CCL showing excellent activity. Optimizing reaction conditions and calculating kinetic parameters revealed that propyl benzoate synthesis using immobilized CCL followed the ternary complex model.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Marcelo Rivas-Astroza, Ivan Paredes, Karlo Guerrero, Silvia Mau, Julian Quintero, Juan Carlos Gentina, Raul Conejeros, German Aroca
Summary: A new kinetic model of Clostridium beijerinckii's Acetone-Butanol-Ethanol fermentation, considering three cell types, accurately replicates batch culture data. The model estimates cell type-specific kinetic parameters, which can improve the operation of ABE fermentation and provide a framework for studying acidogenic and solventogenic metabolic pathways.
JOURNAL OF BIOTECHNOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Yunheng Tang, Yun Huang, Wentian Gan, Ao Xia, Qiang Liao, Xianqing Zhu
Summary: Industrial production processes generate a large amount of inorganic carbon (CO/CO2), which can be used as a carbon substrate for gaseous fermentation to reduce environmental pollution and promote renewable energy. By continuously aerating mixed gases and rabbit feces into the culture, ethanol-producing strains can be enriched. After domestication with CO/CO2, the microbial community structure changed significantly, with ethanol-producing bacteria Blautia becoming dominant and leading to improved fermentation performance.
Article
Chemistry, Physical
Shuhui Wu, Panliang Zhang, Bizhu Sun, Ying Wu, Meiai Huang, Zhuolin Luo, Yingnan Ma, Kewen Tang
Summary: Lipase PS from Pseudomonas cepacia was immobilized on a new support prepared with metal-organic framework (MOF) and polyethyleneimine (PEI), resulting in higher specific activity and enhanced enzyme-substrate affinity compared to free lipase PS. Under optimized conditions, PS@MOF-5-PEI achieved high enantioselectivity and catalytic efficiency for kinetic resolution of TFMP enantiomers.
APPLIED CATALYSIS A-GENERAL
(2023)
Review
Engineering, Environmental
Darijo Sibalic, Anita Salic, Bruno Zelic, Nghiep Nam Tran, Volker Hessel, Krishna D. P. Nigam, Marina Tisma
Summary: Lignocellulosic biorefinery processes for producing bioenergy and value-added products are complex, expensive, energy-intensive, and not environmentally friendly. To overcome these challenges, novel technologies and synergies between existing technologies are needed for sustainable conversion of lignocellulosic biomass into value-added products. This paper investigates cascade processes using ionic liquids and lipases to convert lignocellulosic biomass into value-added products. It provides an overview of the chemical composition of lignocellulosic biomass, solid-state fermentation principles, lipase production by microorganisms on lignocellulosic biomass, ionic liquid utilization for biomass valorization, lipase-catalyzed biotransformation in batch reactors and microreactors, and sustainability assessment using green chemistry metrics.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Lalitendu Das, Ezinne C. Achinivu, Carolina Araujo Barcelos, Eric Sundstrom, Bashar Amer, Edward E. K. Baidoo, Blake A. Simmons, Ning Sun, John M. Gladden
Summary: Ionic liquids (ILs) are important solvents for biomass conversion, with potential to produce biofuels from woody biomass in fire-prone states like California. This study evaluated different types of woody biomass from California and found that pretreatment with ILs like [EOA][OAc] and [Ch][Lys] can efficiently extract glucose and xylose for ethanol production. Blending different feedstocks can further enhance glucose and xylose yields, with the potential to achieve high overall conversion efficiency.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Green & Sustainable Science & Technology
Ting-Yi Huang, Jia Shin Ho, Shuwen Goh, Tzyy Haur Chong
Summary: The study investigated the recovery of ethanol from dilute aqueous solutions using supported ionic liquid membrane (SILM) perstraction. The combination of [THTDP][N(CN)2] as a solvent and polymeric microporous membrane (PVDF-GVHP) showed the best overall performance, with high flux and selectivity maintained for 240 hours. This SILM perstraction system proved to be a promising alternative to energy-intensive purification techniques for extracting ethanol as low as 2 wt% from fermentation broths.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Biophysics
Jakub Hoppe, Ewa Byzia, Radoslaw Drozd, Magdalena Szymanska, Patryk Bielecki, Marcin Smiglak
Summary: In this study, a new series of low transition temperature mixtures (LTTM) were prepared and evaluated for their physicochemical properties and usability in enzymatic transesterification reactions. The addition of various hydrogen bond donors increased the stability and thermal stability of lipase. The transesterification reactions conducted using these mixtures resulted in high yields and high purity of the products.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Engineering, Chemical
Piao Cao, Lin Zheng, Weizhen Sun, Ling Zhao
Summary: Four typical Bronsted acidic ionic liquids (BILs) and concentrated sulphuric acid (H2SO4) were used to catalyze the transesterification of fish oil with ethanol. The results showed that BILs led to higher product quality and fewer side reactions compared to H2SO4. Molecular dynamics simulations indicated that BILs enhanced the contact of fish oil and ethanol at the interface, promoting the transesterification reaction. Furthermore, ultrasound-led liquid-liquid phase emulsification significantly accelerated the reaction rate.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2022)
Article
Engineering, Environmental
Andri Sanjaya, Deni Frans Sakka, Rara Ayu Lestary, Roberty Wisnu Alvania Kartika, Desi Riana Saputri, Damayanti Damayanti, Ria Millati, Wiratni Budhijanto
Summary: This research investigated the conversion of alkaline-pretreated oil palm empty fruit bunch into volatile fatty acids through anaerobic fermentation. The study found that in order to increase the accumulation of VFAs, the growth of methanogens that consume VFAs must be suppressed. It identified temperature and micro aeration as important factors to optimize in order to maximize VFAs production.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Biotechnology & Applied Microbiology
M. Matsumoto, K. Nakao, Y. Tahara
Summary: The study found that both bio-imprinting and water activity affect the catalytic activities and thermostability of lipases during transesterification in ionic liquid and benzene. The impact of imprinting and water activity on reaction activity and kinetic parameters varies in different solvents.
CHEMICAL AND BIOCHEMICAL ENGINEERING QUARTERLY
(2021)
Article
Chemistry, Medicinal
Arbind Kumar, Pradeep Kumar Anand, Saahil Chandel, Anju Shrivatava, Jagdeep Kaur
Summary: This study investigated the impact of the Va1430-Ala mutation in the gene Rv1592c on INH resistance in M. tuberculosis using computational and experimental approaches. The mutation was found to increase stability of the protein and enhance affinity towards INH, potentially leading to modifications that could contribute to drug resistance.
CURRENT COMPUTER-AIDED DRUG DESIGN
(2021)
Article
Acoustics
Gopal Patel, Mahesh D. Patil, Sujit Tangadpalliwar, Shivraj Hariram Nile, Prabha Garg, Guoyin Kai, Uttam Chand Banerjee
Summary: This study focused on modeling and optimizing the production of mycophenolic acid (MPA) from Penicillium brevicompactum using ultrasonic stimulation. By optimizing the ultrasonic treatment conditions, the MPA production was significantly improved.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Amit Kumar Mittal, Uttam Chand Banerjee
Summary: This study synthesized inorganic nanoparticles of various sizes and shapes using plant extracts and phytochemicals, and evaluated their safety, toxicity and efficacy through a series of biological and histopathological assays. Results showed that the nanoparticles exhibited high therapeutic effectiveness with minimal toxic effects on organisms, suggesting their potential for emergency management of life-threatening conditions.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Seema Kirar, Dasharath Chaudhari, Neeraj S. Thakur, Sanyog Jain, Jayeeta Bhaumik, Joydev K. Laha, Uttam C. Banerjee
Summary: A novel A4 type porphyrin photosensitizer was successfully synthesized and encapsulated into gelatin nanoparticles for the development of hydrophilic phototherapeutic nanoagents. The synthesized nanoprobes exhibited good fluorescence performance, indicating potential application in bioimaging. The results of the study demonstrated that these nanoprobes can serve as effective phototherapeutic agents against cancer cells and microbes.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Neeraj S. Thakur, Narattam Mandal, Gopal Patel, Seema Kirar, Y. Nikhileshwar Reddy, Varun Kushwah, Sanyog Jain, Yogeshvar N. Kalia, Jayeeta Bhaumik, Uttam C. Banerjee
Summary: The co-encapsulation of zinc phthalocyanine and quercetin in lipid polymer hybrid nanoparticles significantly enhances the photodynamic anticancer activity. This strategy demonstrates good drug delivery and antitumor effects in in vivo experiments, offering promise as an important approach for future cancer therapy.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2021)
Article
Chemistry, Medicinal
Shailendra Sisodiya, Subarno Paul, Hiteshkumar Chaudhary, Preeti Grewal, Gulshan Kumar, Divine P. Daniel, Biswajit Das, Deepika Nayak, Sankar K. Guchhait, Chanakya N. Kundu, Uttam C. Banerjee
Summary: Two series of compounds were synthesized and screened against cancer cells, with some showing significant apoptotic anti-proliferation effects on cancer cells; they also exhibited relatively less cytotoxicity to normal cells and showed more efficiency in hTopoII alpha inhibition compared to the anticancer drug etoposide.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Linga Banoth, Kezia Devarapalli, Indrani Paul, Karuna Narayan Thete, Sandip Pawar, Uttam Chand Banerjee
Summary: This study isolated a microorganism producing enantioselective lipase for kinetic resolution of racemic alcohols, successfully improving lipase activity and growth conditions. Lipase production and resolution of alcohol compounds were achieved in laboratory scale and bioreactor.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Aashish Sharma, Arbind Kumar, Mudasir Rashid, Ramchandra Vijay Amnekar, Sanjay Gupta, Jagdeep Kaur
Summary: Rv0428c, a hypothetical gene product in Mycobacterium tuberculosis genome, has been identified as a phagosomal acetyl transferase involved in the survival of bacteria under stress conditions. Its expression is upregulated under acidic and nutritive stress conditions, and it shows GCN5 acetyl transferase activity and stability over a wide pH and temperature range.
Review
Chemistry, Physical
Sahil Verma, Rahul Narayanlal Choudhary, Akash Prakash Kanadje, Uttam Chand Banerjee
Summary: Hydrolases, particularly lipases, play a significant role in the pharmaceutical industry by catalyzing the hydrolysis of ester bonds with high specificity and robustness, making them suitable for various organic synthesis procedures. Genetic engineering has further enhanced the catalytic capabilities of lipases, allowing for the development of customized enzymes for greener biocatalytic drug synthesis. Lipases may also play a key role in developing cascade reactions in organic synthesis, making them a promising candidate for future biocatalytic research in the pharmaceutical industry.
Review
Biochemistry & Molecular Biology
Rakesh Kumar, Arbind Kumar, Jagdeep Kaur
Summary: This study presents the application of protein engineering technologies in improving the physical and catalytic properties of enzymes. Protein engineering is commonly used to enhance crucial enzyme characteristics, and a semi-rational approach has emerged as the preferred technology. However, the adoption of an engineering strategy depends on the availability of resources and subject-matter knowledge.
CURRENT PROTEIN & PEPTIDE SCIENCE
(2023)
Article
Microbiology
Parul Singh, Arbind Kumar, Ravindresh Chhabra, Kashmir Singh, Jagdeep Kaur
Summary: This study elucidated the role of MSMEG_5850 in the physiology of mycobacteria. Transcriptome analysis revealed differential expression of 148 genes in an MSMEG_5850 knockout strain. Electrophoretic mobility shift assay and size exclusion chromatography confirmed the binding of MSMEG_5850 to its motif as a monomer. MSMEG_5850 was upregulated under nutritional stress and promoted the survival of mycobacteria.
FUTURE MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Pradeep Kumar Anand, Gagandeep Kaur, Varinder Saini, Jasbinder Kaur, Jagdeep Kaur
Summary: The multigene PE/PPE family is found exclusively in mycobacterium species. Rv3539, identified as PPE63, contains a conserved PPE domain at the N-terminal and a PE-PPE domain at the C-terminal. The study shows that Rv3539 has esterase activity, with the PE-PPE domain demonstrating higher enzyme activity. Additionally, the PPE domain is important for the thermostability and structural integrity of Rv3539.
Article
Microbiology
Pradeep K. K. Anand, Jagdeep Kaur
Summary: The modulation of host immune response is important for the intracellular survival of Mycobacterium tuberculosis. The PPE63 protein was shown to enhance intracellular survival of M. smegmatis by altering cell wall integrity and modulating the host immune response.
CURRENT MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
