Journal
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
Volume 14, Issue 6, Pages 1088-1100Publisher
WILEY
DOI: 10.1111/ijac.12712
Keywords
biological properties; fluorhydroxyapatite; graphene oxide; in situ synthesis; mechanical properties; solubility
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Funding
- Key Laboratory of Inorganic Coating Materials, Chinese Academy of Sciences [KLICM-2014-05]
- Natural Science Foundation of Inner Mongolia Autonomous Region [2014BS0504]
- Inner Mongolia talent development fund [[2016]-149]
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A novel graphene oxide-based fluorhydroxyapatite (GO/FHA) composite is prepared using an in situ chemical synthesis method. The mechanical properties, chemical stability, in vitro bioactivity, and antibacterial properties of the as-synthesized GO/FHA composites with different GO amounts are reported. The result shows that the mechanical properties of the composites are strongly dependent on the adding amount of GO. The result of chemical stability indicates that the substitution of fluorine (F) into the hydroxyapatite (HA) crystal has a positive effect on the dissolution resistance. The in vitro bioactivity assessment shows that the osteoblast proliferation and differentiation ability on GO/FHA composites are improved.
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