Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation
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Title
Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation
Authors
Keywords
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Journal
INTERNATIONAL IMMUNOLOGY
Volume 29, Issue 8, Pages 365-375
Publisher
Oxford University Press (OUP)
Online
2017-09-21
DOI
10.1093/intimm/dxx049
References
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Note: Only part of the references are listed.- Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
- (2017) Masahiro Okada et al. Epigenetics & Chromatin
- Control of Foxp3 stability through modulation of TET activity
- (2016) Xiaojing Yue et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Vitamin C Facilitates Demethylation of theFoxp3Enhancer in a Tet-Dependent Manner
- (2016) Varun Sasidharan Nair et al. JOURNAL OF IMMUNOLOGY
- Roles of transcription factors and epigenetic modifications in differentiation and maintenance of regulatory T cells
- (2016) Takashi Sekiya et al. MICROBES AND INFECTION
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Induced Regulatory T Cells: Their Development, Stability, and Applications
- (2016) Mitsuhiro Kanamori et al. TRENDS IN IMMUNOLOGY
- Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism
- (2016) Alain R. Weber et al. Nature Communications
- Induced Foxp3+ T Cells Colonizing Tolerated Allografts Exhibit the Hypomethylation Pattern Typical of Mature Regulatory T Cells
- (2016) Robert Hilbrands et al. Frontiers in Immunology
- Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate
- (2016) Angelika Schmidt et al. PLoS One
- Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
- (2015) Min-Zu Wu et al. CANCER RESEARCH
- Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis
- (2015) Ruili Yang et al. IMMUNITY
- Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
- (2015) Tuomas Laukka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
- (2015) B-H Yang et al. Mucosal Immunology
- The microbiota regulates type 2 immunity through ROR t+ T cells
- (2015) C. Ohnmacht et al. SCIENCE
- Maternal TET3 is dispensable for embryonic development but is required for neonatal growth
- (2015) Yu-ichi Tsukada et al. Scientific Reports
- Function of a Foxp3 cis -Element in Protecting Regulatory T Cell Identity
- (2014) Xudong Li et al. CELL
- Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
- (2014) Yongqiang Feng et al. CELL
- Cutting Edge: Antigen-Specific TGF -Induced Regulatory T Cells Suppress Th17-Mediated Autoimmune Disease
- (2014) E. N. Huter et al. JOURNAL OF IMMUNOLOGY
- Prevention of Allogeneic Cardiac Graft Rejection by Transfer of Ex Vivo Expanded Antigen-Specific Regulatory T-Cells
- (2014) Fumika Takasato et al. PLoS One
- TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma
- (2014) Christopher J. Mariani et al. Cell Reports
- Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation
- (2013) Lulu Hu et al. CELL
- Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine
- (2013) Emily A. Minor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Smad2/3 and IRF4 Play a Cooperative Role in IL-9-Producing T Cell Induction
- (2013) T. Tamiya et al. JOURNAL OF IMMUNOLOGY
- Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus
- (2013) A. Toker et al. JOURNAL OF IMMUNOLOGY
- Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
- (2013) Kathryn Blaschke et al. NATURE
- Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis
- (2013) Takashi Sekiya et al. NATURE IMMUNOLOGY
- TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity
- (2013) Go Muto et al. PLoS One
- Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes
- (2013) Yohko Kitagawa et al. Frontiers in Immunology
- T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
- (2012) Naganari Ohkura et al. IMMUNITY
- Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut
- (2012) Susan M. Schlenner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TGF-β Drives DNA Demethylation
- (2012) David Wotton MOLECULAR CELL
- TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex
- (2012) Gobi Thillainadesan et al. MOLECULAR CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Transcription Factor Smad-Independent T Helper 17 Cell Induction by Transforming-Growth Factor-β Is Mediated by Suppression of Eomesodermin
- (2011) Kenji Ichiyama et al. IMMUNITY
- IL-2 Controls the Stability of Foxp3 Expression in TGF- -Induced Foxp3+ T Cells In Vivo
- (2011) Q. Chen et al. JOURNAL OF IMMUNOLOGY
- Smad2 and Smad3 Are Redundantly Essential for the TGF- -Mediated Regulation of Regulatory T Plasticity and Th1 Development
- (2010) T. Takimoto et al. JOURNAL OF IMMUNOLOGY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells
- (2009) Yoshinori Yoshida et al. Cell Stem Cell
- Alloantigen-specificde novo-induced Foxp3+Treg revertin vivoand do not protect from experimental GVHD
- (2009) Christian Koenecke et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
- (2009) Noriko Komatsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- DNA methylation controls Foxp3 gene expression
- (2008) Julia K. Polansky et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
- (2008) Yuri P. Rubtsov et al. IMMUNITY
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