Article
Medicine, General & Internal
Julien Beauquis, Hugo M. Setbon, Charles Dassargues, Pierre Carsin, Sam Aryanpour, Jean-Pierre Van Nieuwenhuysen, Julian G. Leprince
Summary: The objective of this study was to evaluate the short-term evolution of pain and the treatment success of full pulpotomy as permanent treatment for irreversible pulpitis. The results showed that there was no significant difference between full pulpotomy and root canal treatment in terms of short-term pain evolution, clinical success, and global success. However, there was a significant difference in radiographic success. This study adds to the existing literature supporting the use of pulpotomy as an acceptable and conservative treatment option for a larger population of dentists.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Biomedical
Ragini Amarnani, Pravin Shende
Summary: Microneedle technology plays an important role in biomedical engineering for their less intrusive access to the skin and various therapeutic applications. However, there are still challenges in the scale-up technique and drug delivery pattern. Microneedles can be considered as a single tool for diagnostic sensing and therapeutic administration. This review article discusses different types of microneedles and their fabrication methods, as well as their applications in treating various medical conditions.
BIOMEDICAL MICRODEVICES
(2022)
Article
Agriculture, Dairy & Animal Science
Josephine B. Rose, Austin Leeds, Linda M. Yang, Rachel LeMont, Melissa A. Fayette, Jeffry S. Proudfoot, Michelle R. Bowman, Allison Woody, James Oosterhuis, David A. Fagan
Summary: Tusk fractures in elephants can lead to various outcomes, from self-healing to life-threatening infection. A survey of global elephant veterinarians revealed that larger pulp canal diameter at the time of fracture and the use of tap water during treatment increase the risk of infected and inflamed pulp. Endodontic treatment reduced the risk of tusk extraction. These findings can guide clinical decision making for elephant managers and clinicians.
Article
Dentistry, Oral Surgery & Medicine
Ana Flavia Almeida Barbosa, Carolina Oliveira de Lima, Estefano Borgo Sarmento, Guilherme Goncalves da Cunha, Luciana Moura Sassone, Ricardo Tadeu Lopes, Emmanuel Joao Nogueira Leal da Silva
Summary: This study evaluated the impact of root canal preparation in teeth with ultraconservative access cavities on the development of dentinal microcracks using nondestructive longitudinal micro-CT imaging. The results showed that regardless of the access cavity and instrumentation system, root canal preparation did not create new dentinal microcracks.
JOURNAL OF ENDODONTICS
(2022)
Article
Surgery
George Skouras, Athanasios Skouras, Elena Skoura
Summary: This study aimed to examine the common problems faced by the senior author in face lifts due to previous minimally invasive procedures and demonstrate the methods used to solve them. Among the 552 face lift patients analyzed, 207 had undergone minimally invasive procedures before. The problems frequently encountered included cheek fat atrophy, scar tissue formation, and the use of large-volume injectables. Surgeons need to be trained to evaluate and address these problems during a face lift.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Review
Biotechnology & Applied Microbiology
Hisham Elnawam, Menatallah Abdelmougod, Ahmed Mobarak, Mai Hussein, Hamdy Aboualmakarem, Michael Girgis, Rania El Backly
Summary: Regenerative endodontic procedures and minimally invasive endodontics are important methods for treating immature necrotic permanent teeth. They promote root maturation and preserve tooth structure. However, finding better disinfecting agents and strategies, as well as improving existing treatment protocols, are crucial for achieving optimal outcomes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Immunology
Edmund Huang, Michael Mengel, Marian C. Clahsen-van Groningen, Annette M. Jackson
Summary: With the advancements in minimally invasive biomarkers in kidney transplantation, new strategies for monitoring allograft health are emerging. However, the current available data does not support the use of blood and urine-based biomarkers as stand-alone diagnostic tests. More studies are needed to evaluate their ability to distinguish different types of rejection and serve as adjuncts to histology, in order to elevate these biomarkers to diagnostic tests.
Article
Dentistry, Oral Surgery & Medicine
Chaehwan Lee, Minju Song
Summary: This study reviewed failed cases after regenerative endodontic procedures (REPs) and proposed a treatment algorithm to assist clinical decision-making. The primary reasons for treatment failure were persistent infection and root resorption. Consideration of the treatability of the tooth, accessibility to the canal, and the presence of an apical seat were identified as key factors in obtaining successful outcomes in clinical decision-making.
JOURNAL OF ENDODONTICS
(2022)
Article
Medicine, General & Internal
Lei Wang, Dan-Jie Meng, Ying-Ze Yang, Yan-Qing Huang, Qian Cao, Zi-Hao Yao, Lu-Li Tian
Summary: This study investigated the clinical effect of ultrasound technology combined with minimally invasive root canal surgery in patients with pulpitis. The results showed that this method can improve the chewing function of patients, shorten the anesthesia time, effectively relieve pain, and has a high level of safety.
ACTA MEDICA MEDITERRANEA
(2022)
Review
Biotechnology & Applied Microbiology
Berkan Celikten, Mehrdad Koohnavard, Aysenur Oncu, Fatma Semra Sevimay, Ayse Isil Orhan, Kaan Orhan
Summary: This study evaluated the minimally invasive approach in root canal treatment, finding that with appropriate case selection, minimally invasive treatment can provide a good prognosis while maintaining the tooth structure.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
(2021)
Article
Health Care Sciences & Services
Jiaqi Wu, Modi Heng, Yunyang Bai
Summary: This study introduces a novel dice-inspired multifunctional 3D printing guided splint that allows minimal invasive access cavity preparation and canal orifice identification. The experimental results show that this new splint can help dental practitioners achieve accurate, conservative, and safe cavity access when dealing with teeth with anatomical malformations.
TECHNOLOGY AND HEALTH CARE
(2023)
Review
Medicine, General & Internal
Kai Chen, Xing Ran, Yan Wang
Summary: This case report presents the presence of two separate root canals in the palatal root of a maxillary first molar. Root canal treatment was performed successfully using an endodontic microscope and cone-beam computed tomography (CBCT).
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Medicine, General & Internal
Yuki Kojima, Ryozo Sendo
Summary: Tooth loss is a predictor of decreased longevity in aging humans. This report proposes a novel therapy for treating pulpitis, which combines antibiotics, steroids, and ultrasound-guided trigeminal nerve block (UGTNB) to protect the dental pulp. This new treatment could improve tooth longevity and oral health.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Multidisciplinary Sciences
Maryam Gholinejad, Egidius Pelanis, Davit Aghayan, Asmund Avdem Fretland, Bjorn Edwin, Turkan Terkivatan, Ole Jakob Elle, Arjo J. Loeve, Jenny Dankelman
Summary: This paper introduces a novel approach called surgical process modelling, which aims to simplify the challenges in improving surgeries by quantitatively analyzing surgical activities. The approach is applied to analyze different Minimally Invasive Liver Treatments (MILTs) and a generic surgical process model is introduced. The model is established at three different granularity levels and includes all surgical and interventional activities, providing a foundation for extensive quantitative analysis and simulations.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Carmine Zoccali, Mariangela Novello, Francesco Arrigoni, Alessandra Scotto di Uccio, Dario Attala, Virginia Ferraresi
Summary: Osteoblastoma is a rare bone tumor that is difficult to diagnose. Surgical excision is the gold standard treatment, but minimally invasive radiological techniques can also be considered. Surgical indications include lesions close to nerves or joints, unclear diagnosis, and risk of fracture.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Dentistry, Oral Surgery & Medicine
Ikhlas El-Karim, Henry F. Duncan, Venkateshbabu Nagendrababu, Mike Clarke
Summary: Endodontic therapy aims to preserve teeth by preventing and treating apical disease. Traditional treatment outcome reporting focuses on clinician-reported outcomes (CROs), while patient-reported outcomes (PROs) are less commonly employed. This lack of consensus in outcome reporting leads to heterogeneity, which hinders meta-analysis, guidelines development, and clinical decision making. The establishment of a core outcome set (COS) in endodontics can reduce these effects.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Review
Dentistry, Oral Surgery & Medicine
Venkateshbabu Nagendrababu, Henry F. Duncan, Paul V. Abbott, Paul M. H. Dummer
Summary: Reporting guidelines play a crucial role in improving the quality and reliability of publications in the field of dental traumatology. The PRIDE suite of reporting guidelines provides a standardized template for manuscript development and ensures adherence to global reporting standards. Editors endorsing these guidelines can expect improved reporting quality in manuscripts submitted to their journals.
DENTAL TRAUMATOLOGY
(2023)
Editorial Material
Dentistry, Oral Surgery & Medicine
Henry F. Duncan
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Review
Dentistry, Oral Surgery & Medicine
Henry F. Duncan, Ikhlas El-Karim, Paul M. H. Dummer, John Whitworth, Venkateshbabu Nagendrababu
Summary: The promotion of minimally invasive treatments focused on maintaining pulp vitality is a priority in endodontics. This review discusses the outcomes of partial and full pulpotomy procedures and analyzes various factors that influence the results. Current evidence suggests that age, gender, tooth type, and intraoperative pulpal hemorrhage do not significantly impact the outcome, while factors such as caries depth, pulp inflammation, capping materials, and restoration integrity may affect the success. Further experimental research is needed to definitively determine the success of pulpotomy procedures.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Venkateshbabu Nagendrababu, Henry F. Duncan, Ashraf F. Fouad, Lise-Lotte Kirkevang, Peter Parashos, Maria Pigg, Michael Vaeth, Jayakumar Jayaraman, Nandini Suresh, Ana Arias, Emma Wigsten, Paul M. H. Dummer
Summary: This article outlines the development process of the PROBE 2023 guidelines, which provide a consensus-based approach for reporting observational studies in endodontics. The guidelines were developed through a series of expert input and feedback, resulting in an 11-section, 58-item checklist aimed at improving the quality of reporting in this field.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ashima Jassal, Ruchika Roongta Nawal, Seema Yadav, Sangeeta Talwar, Sudha Yadav, Henry Fergus Duncan
Summary: This study compared the clinical and radiographic outcomes of partial pulpotomy and full pulpotomy using Biodentine in mature permanent molar teeth with symptoms of irreversible pulpitis. The results showed that partial pulpotomy yielded similar results to full pulpotomy in terms of clinical and radiographic treatment outcomes.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Editorial Material
Dentistry, Oral Surgery & Medicine
Henry F. Duncan
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Venkateshbabu Nagendrababu, Henry F. F. Duncan, Ashraf F. F. Fouad, Lise-Lotte Kirkevang, Peter Parashos, Maria Pigg, Michael Vaeth, Jayakumar Jayaraman, Nandini Suresh, Aleksandar Jakovljevic, Paul M. H. Dummer
Summary: Observational studies are crucial for assessing the prevalence and impact of diseases and interventions. However, there is currently a lack of reporting guidelines for observational studies in the field of Endodontics. To address this gap, the PRIDE team has developed the PROBE 2023 guidelines, which integrate existing checklists and principles. This document serves as a guide for authors, providing explanations and examples for each item in the PROBE 2023 checklist.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Michaela Kearney, Paul R. Cooper, Anthony J. Smith, Henry F. Duncan
Summary: Exciting opportunities exist within regenerative endodontics for the development of targeted biomaterials that harness epigenetic machinery to control pulpitis and stimulate repair. In this study, small RNA sequencing and bioinformatic analysis were used to establish a miRNA expression profile for mineralising dental pulp cells (DPCs) and examine their interaction with histone deacetylase inhibitors and DNA methyltransferase inhibitors. The results showed that these inhibitors induced mineralisation but reduced cell growth, suggesting an increased and dynamic interaction between miRNA and epigenetic modifiers during DPC reparative processes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nursing
Niamh Kelly, Bronagh Blackwood, Nicki Credland, Louise Stayt, Christine Causey, Lewis Winning, Daniel F. McAuley, Fionnuala T. Lundy, Ikhlas El Karim
Summary: The study aimed to investigate oral care practices in adult ICUs in the UK and found significant variability in the provision and methods of oral care, as well as a lack of standardization in oral assessments and care plans. It highlights the need for optimal oral care standards and further research to improve oral care for ICU patients.
NURSING IN CRITICAL CARE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anas Salami, Ikhlas El Karim, Fionnuala Lundy, Tom Loney, Michael Donaldson, Ciaran O'Neill
Summary: This study analyzed anonymous data from mothers in Northern Ireland who gave birth between 2012 and 2017 and their children's dental service use. It found a negative relationship between maternal diabetes status and offspring's use of dental services, contrary to previous research. Further investigation using this valuable data resource is warranted.
Article
Dentistry, Oral Surgery & Medicine
Venkateshbabu Nagendrababu, Clovis M. M. Faggion Jr, Vellore Kannan Gopinath, Srinivasan Narasimhan, Henry F. F. Duncan, Liran Levin, Paul V. V. Abbott, Paul M. H. Dummer
Summary: The methodological quality of systematic reviews (SRs) with meta-analysis in the field of traumatic dental injuries was evaluated using the AMSTAR 2 tool. The results showed that the majority of studies had low or critically low methodological quality. Journal impact factor and year of publication significantly influenced the methodological quality.
DENTAL TRAUMATOLOGY
(2023)
Article
Engineering, Biomedical
Henry F. Duncan, Yoshifumi Kobayashi, Michaela Kearney, Emi Shimizu
Summary: This opinion-led review paper emphasizes the importance of innovative translational research in vital-pulp-treatment (VPT) and discusses the challenges in implementing evidence in clinics. The traditional dentistry approach, which is expensive and invasive, lacks a biological perspective. Recent research focuses on developing minimally-invasive biologically-based 'fillings' that preserve dental pulp and shift the paradigm towards smart restorations targeting biological processes. The potential use of histone-deacetylase (HDAC) inhibitors in stimulating pro-regenerative effects and enhancing biomaterial-driven tissue responses in VPT is analyzed in this article.
BIOACTIVE MATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Valerie Chevalier, Anais Le Fur Bonnabesse, B. Honari, H. F. Duncan
Summary: This study aimed to identify and explain the main sources of stress among preclinical and clinical dental undergraduate students, with a specific focus on stressors related to endodontics. The results showed that performance pressure, workload, and clinical training were the most stressful areas for students in all years. In early years, endodontic students experienced stress related to self-efficacy beliefs, endodontic clinical training, and faculty and administration. In later years, the stress came from endodontic patient treatment, performance pressure in endodontics, and clinical training. Qualitative analysis revealed that patients and COVID-19 played important roles in student stress.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Review
Dentistry, Oral Surgery & Medicine
Hany Mohamed Aly Ahmed, Ikhlas El-karim, Henry F. Duncan, Gabriel Krastl, Kerstin Galler
Summary: This review discusses the implications of root anatomy, pulp chamber, and canals on pulpotomy and revitalization procedures. Pulpotomy procedures can avoid the challenges faced during root canal treatment, but a meticulous understanding of pulp chamber anatomy is required. The complex relationship between the root canal system and outcomes of revitalization procedures in necrotic multi-rooted teeth with mature roots needs further research.
CLINICAL ORAL INVESTIGATIONS
(2023)
