Article
Medicine, General & Internal
Carlos Constantin Otto, Zoltan Czigany, Daniel Heise, Philipp Bruners, Drosos Kotelis, Sven Arke Lang, Tom Florian Ulmer, Ulf Peter Neumann, Christian Klink, Jan Bednarsch
Summary: This study investigated clinical predictors of postoperative mortality in patients undergoing surgical and/or interventional treatment for acute mesenteric ischemia (AMI). The study identified leukocytes, lactate, bilirubin, creatinine, etiology, and portomesenteric vein gas as independent predictors of postoperative mortality.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Alexandre Nuzzo, Kevin Guedj, Sonja Curac, Claude Hercend, Claude Bendavid, Nathalie Gault, Alexy Tran-Dinh, Maxime Ronot, Antonino Nicoletti, Yoram Bouhnik, Yves Castier, Olivier Corcos, Katell Peoc'h
Summary: This study aimed to assess the accuracy of three promising circulating biomarkers for diagnosing AMI, including citrulline, I-FABP, and d-lactate. The results showed that citrulline concentration was significantly lower in AMI patients compared to controls, but it had low accuracy in diagnosing AMI. I-FABP and d-lactate did not show statistical differences between AMI patients and controls, indicating a need for further research to identify new biomarkers.
SCIENTIFIC REPORTS
(2021)
Article
Gastroenterology & Hepatology
Rainer Grotelueschen, Verena Miller, Lena M. Heidelmann, Nathaniel Melling, Tarik Ghadban, Katharina Grupp, Matthias Reeh, Maria-Noemi Welte, Faik Guntac Uzunoglu, Jakob R. Izbicki, Kai A. Bachmann
Summary: Diagnosing acute mesenteric ischemia is challenging due to low sensitivity and specificity of established parameters. Exploratory laparotomy remains the most reliable diagnostic method for detecting mesenteric infarction. New diagnostic parameters are needed to improve accuracy in diagnosis.
Article
Surgery
Satoshi Karasawa, Talza-alzi Nalzada, Mamoru Sato, Talzu Miyasho, Tadanaga Shimada, Talzu Oshima, Koichi Suda, Koichiro Shinozalzi, Shigeto Oda
Summary: The study demonstrated that blood levels of cell-free DNA were significantly higher in the AMI model than in sham and abdominal sepsis models, and they were positively correlated with the pathologic ischemia severity score. Additionally, higher levels of paraoxonase-1 were found in the AMI models compared to the abdominal sepsis models, suggesting a potential role in the differential diagnosis of mesenteric ischemia.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Arnaud Juif, Paul Calame, Hadrien Winiszewski, Celia Turco, Pierre Verdot, Sebastien Pili-Floury, Gael Piton, Eric Delabrousse
Summary: The study showed that abdominal atherosclerosis, especially in the SMA, is associated with poorer outcomes in patients with nonocclusive mesenteric ischemia (NOMI).
EUROPEAN JOURNAL OF RADIOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Jana Smalcova, Jan Belohlavek
Summary: This paper summarizes current knowledge on pathophysiology, diagnosis, treatment, and prognostic significance of NOMI in CA patients.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pierre Verdot, Paul Calame, Hadrien Winiszewski, Franck Grillet, Alexandre Malakhia, Zaher Lakkis, Maxime Ronot, Sebastien Pili-Floury, Gael Piton, Eric Delabrousse
Summary: The absence of bowel wall enhancement remains the key CT feature for diagnosing transmural necrosis in non-occlusive mesenteric ischemia, regardless of the bowel segment involved. Inter-reader agreement of CT features is lower in the colon compared to the small bowel. Proximal TN is associated with poorer overall survival.
EUROPEAN RADIOLOGY
(2021)
Article
Surgery
Karri Kase, Annika Reintam Blaser, Kadri Tamme, Merli Mandul, Alastair Forbes, Peep Talving, Marko Murruste
Summary: This study conducted a population-based research on AMI in Estonia and found an incidence rate of 8.7 per 100,000. Most cases were female and the main comorbidities included hypertension, atherosclerosis, and atrial fibrillation. Superior mesenteric artery occlusion was the primary cause of AMI, and active treatment was associated with lower mortality rates.
WORLD JOURNAL OF SURGERY
(2023)
Article
Emergency Medicine
Dillon Warr, Troy Rivera, Michelle Romeo
Summary: This case report describes a non-occlusive acute mesenteric ischemia caused by sildenafil-induced transient hypotension. The patient received rapid fluid resuscitation in the emergency department and was discharged after symptom resolution during a 7-day inpatient stay.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Antoine Topolsky, Olivier Pantet, Lucas Liaudet, Christine Sempoux, Alban Denys, Jean-Francois Knebel, Sabine Schmidt
Summary: This study evaluated the influence of vasoconstrictor agents on vasoconstriction and bowel ischemia detected by MDCT in patients with non-occlusive mesenteric ischemia. The results showed that patients treated with vasoconstrictor agents had more severe mesenteric artery vasoconstriction and more frequent abdominal organ infarcts compared to patients not treated with vasoconstrictor agents. The use of vasoconstrictor agents also led to lower blood pressure and hemoglobin levels, indicating worse clinical condition.
EUROPEAN RADIOLOGY
(2023)
Article
Critical Care Medicine
Matti Tolonen, Aurora Lemma, Pirkka Vikatmaa, Erno Peltola, Panu Mentula, Patrick Bjorkman, Ari Leppaniemi, Ville Sallinen
Summary: Implementing a pathway and care bundle led to improved management and outcomes in patients with acute mesenteric ischemia, with significant improvements in diagnosis, treatment, and 30-day mortality observed in the postgroup.
JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
(2021)
Article
Surgery
Antonio Brillantino, Michele Lanza, Massimo Antropoli, Alfonso Amendola, Simone Squillante, Vincenzo Bottino, Adolfo Renzi, Maurizio Castriconi
Summary: For non-critical patients with limited acute mesenteric ischemia, the damage control approach by two-step surgical procedure may provide better clinical outcomes compared to one-step surgical treatment, reducing the risks of anastomosis dehiscence and the need for ileostomy.
UPDATES IN SURGERY
(2022)
Article
Medicine, Research & Experimental
Abolfazl Badripour, Mohamad Behzadi, Amin Hassanipour, Pasha Reza Shams Azar, Alireza Rahbar, Zhaleh Abbaslou, Elnaz Ehghaghi, Ashkan Piranviseh, Mohammad Mahdi Khavandi, Seyed Mohsen Ahmadi-Tafti, Mohammad Ashouri, Zahra Ebrahim Soltani, Ahmadreza Dehpour
Summary: This study aimed to evaluate the effects of Albendazole pretreatment on mesenteric ischemia reperfusion (MIR) injury. The findings demonstrated that Albendazole could ameliorate the inflammatory response and enhance the ischemia threshold following MIR injury.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Gastroenterology & Hepatology
Simon Bourcier, Julian Klug, Lee S. Nguyen
Summary: Acute mesenteric ischemia (AMI) is a severe condition associated with poor prognosis, and non-occlusive mesenteric ischemia (NOMI) is a particular form of AMI prevalent in critically ill patients. Accurate diagnosis is crucial for NOMI management, but the lack of tools for detection has hindered improvement in NOMI prognosis. Artificial intelligence (AI) offers the potential for accurate diagnosis through machine-learning-based algorithms.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Aida Ksouri, Pauline Copin, Fanny Bonvalet, Lilian Bozi, Dominique Cazals-Hatem, Lorenzo Garzelli, Yves Panis, Emmanuel Weiss, Yves Castier, Yoram Bouhnik, Olivier Corcos, Valerie Vilgrain, Maxime Ronot, Alexandre Nuzzo
Summary: Colonic involvement in patients with acute mesenteric ischemia is associated with increased morbidity and mortality, and should be carefully assessed during initial CT scans.
EUROPEAN RADIOLOGY
(2022)
Editorial Material
Nutrition & Dietetics
Jean-Charles Preiser, Steven Laureys, Arthur Raymond Hubert van Zanten, Andre Van Gossum
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2021)
Review
Endocrinology & Metabolism
Annika Reintam Blaser, Arthur Raymond Hubert van Zanten
Summary: Various electrolyte disorders are common in critically ill patients, with refeeding syndrome being identified by hypophosphatemia, hypokalemia, and hypomagnesemia occurring after feeding initiation. In addition to correcting electrolyte levels, reducing caloric intake may help improve the outcome of refeeding syndrome.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
(2021)
Review
Critical Care Medicine
Hanneke Pierre Franciscus Xaverius Moonen, Karin Josephina Hubertina Beckers, Arthur Raymond Hubert van Zanten
Summary: Indirect calorimetry is strongly recommended for guiding nutrition therapy in critically ill patients, but its superiority in clinical trials is not yet proven. Energy expenditure is influenced by various factors, and personalized calculation is needed for optimal nutrition support.
JOURNAL OF INTENSIVE CARE
(2021)
Article
Nutrition & Dietetics
W. A. C. Koekkoek, K. Hettinga, J. H. M. de Vries, A. R. H. van Zanten
Summary: ICU patients had lower plasma levels of selenium, beta-carotene, vitamin C, and vitamin E compared to healthy controls upon admission. Vitamin C levels dropped significantly during the first days of ICU admission, while beta-carotene and vitamin E levels increased after 5-7 days. Micronutrient levels were not associated with severity of illness, C-reactive protein (CRP), or micronutrient intake.
CLINICAL NUTRITION
(2021)
Review
Critical Care Medicine
Hanneke Pierre Franciscus Xaverius Moonen, Arthur Raymond Hubert Van Zanten
Summary: Insight into body composition using bioelectric impedance analysis (BIA) is valuable in the ICU setting, but its validity and interpretation in critically ill patients remain uncertain. Correlations have been found between BIA parameters and adverse outcomes in critical illness, but cut-off values and reference standards are still unclear, necessitating further research and validation.
CURRENT OPINION IN CRITICAL CARE
(2021)
Article
Nutrition & Dietetics
Rianne Slingerland-Boot, Marianne Bouw-Ruiter, Christiaan van Manen, Sesmu Arbous, Arthur van Zanten
Summary: The study evaluates the performance of video-assisted feeding tube placement in critically ill patients, showing a success rate of 58% for post-pyloric placement and 96.8% for gastric placement. IRIS technology was able to detect tracheal misplacements and had few adverse events.
CLINICAL NUTRITION
(2021)
Article
Infectious Diseases
Jochem B. Buil, Arthur R. H. van Zanten, Robbert G. Bentvelsen, Tom A. Rijpstra, Bram Goorhuis, Sanne van der Voort, Linda J. Wammes, Jeroen A. Janson, Max Melchers, Moniek Heusinkveld, Willem J. G. Melchers, Ed J. Kuijper, Paul E. Verweij
Summary: This study describes four secondary fungal infections caused by Mucorales species in COVID-19 patients, with three cases occurring in ICU. The majority of the cases were male, and the clinical presentations varied, with infections occurring in patients with and without diabetes mellitus.
Article
Nutrition & Dietetics
Hanneke Pierre Franciscus Xaverius Moonen, Bert Strookappe, Arthur Raymond Hubert van Zanten
Summary: COVID-19 ICU survivors are vulnerable to ICU-acquired weakness, but show a better tendency towards physical rehabilitation compared to non-COVID pneumosepsis ICU survivors, particularly in terms of Medical Research Council Sum-Score (MRC-SS) and Chelsea Critical Care Physical Assessment tool (CPAx). COVID-19 ICU patients may benefit from early, more intensive physical therapy.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Emergency Medicine
Anneke Gielen, Kristine Koekkoek, Marijke van der Steen, Martijn-Looijen Looijen, Arthur R. H. van Zanten
Summary: The study analyzed data from 53,180 patients admitted to a general hospital ward, finding that a high-risk initial EWS was associated with increased in-hospital mortality, ICU admission rate, and prolonged hospital LOS.
WESTERN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Nutrition & Dietetics
H. Slingerland-Boot, S. Adhikari, M. R. Mensink, A. R. H. van Zanten
Summary: This study evaluated the performance of an unevaluated device for determining energy requirements in mechanically ventilated critically ill patients. The Beacon indirect calorimeter accurately estimated resting energy expenditure compared to the gold standard Quark device. Predictive equations performed poorly in this population.
CLINICAL NUTRITION ESPEN
(2022)
Letter
Nutrition & Dietetics
Robert G. Martindale, Stanislaw Klek, Zudin Puthucheary, Martin D. Rosenthal, Christian Stoppe, Arthur R. H. van Zanten, Dan L. Waitzberg, Paul E. Wischmeyer
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Rianne Slingerland-Boot, Ino van der Heijden, Nienke Schouten, Luuk Driessen, Sjoerd Meijer, Marco Mensink, Arthur van Zanten
Summary: This study aims to describe energy and protein intake in detail over the entire post-ICU hospitalization period and explore associations between protein intake and clinical outcomes. The findings show that most patients did not meet energy and protein targets in the post-ICU hospitalization period. Nutrition performance was highly dependent on the route of nutrition, with the best intake observed in patients receiving (supplemental) enteral nutrition.
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Rianne Slingerland-Boot, Eveline Rooijakkers, Kristine Koekkoek, Dick van Blokland, Sesmu Arbous, Arthur van Zanten
Summary: This study evaluates the associations between macronutrient intake and clinical outcomes in ICU patients with refeeding hypophosphatemia. The results suggest that high protein intake during the first three days of ICU admission is associated with increased 6-month mortality.
CLINICAL NUTRITION ESPEN
(2023)
Article
Nutrition & Dietetics
Max Melchers, Anoek Jacqueline Hubertine Hermans, Suzanne Belia Hulsen, Imre Willemijn Kehinde Kouw, Arthur Raymond Hubert van Zanten
Summary: This study highlights the importance of providing adequate nutritional therapy to COVID-19 patients in the ICU who require invasive mechanical ventilation. Meeting over 80% of the protein goals based on BIA-derived FFM was associated with lower mortality rates.
CLINICAL NUTRITION
(2023)
Review
Critical Care Medicine
Jean-Charles Preiser, Yaseen M. Arabi, Mette M. Berger, Michael Casaer, Stephen McClave, Juan C. Montejo-Gonzalez, Sandra Peake, Annika Reintam Blaser, Greet Van den Berghe, Arthur van Zanten, Jan Wernerman, Paul Wischmeyer
Summary: This article provides practical guidance on enteral nutrition in critically ill patients. It covers topics such as the safe timing for low-dose enteral nutrition, protein intake, assessment of refeeding syndrome, and signs of gastrointestinal intolerance.