Journal
CURRENT GENE THERAPY
Volume 15, Issue 2, Pages 201-214Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1566523215666150122130047
Keywords
Anti-gene; efficacious; RNAi; safe; therapeutic
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Funding
- Department of Biotechnology, Government of India
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RNAi based therapeutics hold s great promises to be an efficient strategy of the anti-gene realm in context of its therapeutic applications; however, despite significant potentials, its full efficacy cannot be realized in real sense owing to various confronts that plague its advancement. Efforts need to be driven for the development of specific and efficacious strategies to subdue some of their crucial constraints towards successes in clinics. This article will present the major impediments that encumber successful translation of siRNA concept into reality and the ongoing research endeavours to get through those stumbling blocks along with their inadequacies.
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