Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice

Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus

(2015) Guey-Chuen Perng et al.   CURRENT EYE RESEARCH

HLA-A02:01–Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8+T Cells from Seropositive Asymptomatic Individuals and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpes

(2015) Ruchi Srivastava et al.   JOURNAL OF IMMUNOLOGY

Therapeutic Immunization with a Mixture of Herpes Simplex Virus 1 Glycoprotein D-Derived “Asymptomatic” Human CD8+T-Cell Epitopes Decreases Spontaneous Ocular Shedding in Latently Infected HLA Transgenic Rabbits: Association with Low Frequency of Local PD-1+TIM-3+CD8+Exhausted T Cells

(2015) Arif A. Khan et al.   JOURNAL OF VIROLOGY

Phenotypic and Functional Characterization of Herpes Simplex Virus Glycoprotein B Epitope-Specific Effector and Memory CD8+T Cells from Symptomatic and Asymptomatic Individuals with Ocular Herpes

(2015) Arif A. Khan et al.   JOURNAL OF VIROLOGY

Establishment of HSV1 Latency in Immunodeficient Mice Facilitates Efficient In Vivo Reactivation

(2015) Chandran Ramakrishna et al.   PLoS Pathogens

CXCL1 but Not IL-6 Is Required for Recurrent Herpetic Stromal Keratitis

(2014) D. M. West et al.   JOURNAL OF IMMUNOLOGY

Animal models of herpes simplex virus immunity and pathogenesis

(2014) Christina M. Kollias et al.   JOURNAL OF NEUROVIROLOGY

Asymptomatic memory CD8+T cells

(2014) Arif Azam Khan et al.   Human Vaccines & Immunotherapeutics

Asymptomatic HLA-A*02:01-Restricted Epitopes from Herpes Simplex Virus Glycoprotein B Preferentially Recall Polyfunctional CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect HLA Transgenic Mice against Ocular Herpes

(2013) X. Dervillez et al.   JOURNAL OF IMMUNOLOGY

Recurrent Herpetic Stromal Keratitis in Mice: A Model for Studying Human HSK

(2012) Patrick M. Stuart et al.   Clinical & Developmental Immunology

CD8+ T Cells Suppress Viral Replication in the Cornea but Contribute to VEGF-C-Induced Lymphatic Vessel Genesis

(2012) C. D. Conrady et al.   JOURNAL OF IMMUNOLOGY

Herpes Simplex Epithelial and Stromal Keratitis: An Epidemiologic Update

(2012) Asim V. Farooq et al.   SURVEY OF OPHTHALMOLOGY

Of mice and not humans: How reliable are animal models for evaluation of herpes CD8+-T cell-epitopes-based immunotherapeutic vaccine candidates?

(2011) Gargi Dasgupta et al.   VACCINE

A Novel HLA (HLA-A*0201) Transgenic Rabbit Model for Preclinical Evaluation of Human CD8 + T Cell Epitope-Based Vaccines against Ocular Herpes

(2010) Aziz A. Chentoufi et al.   JOURNAL OF IMMUNOLOGY

Exacerbation of corneal scarring in HSV-1 gK-immunized mice correlates with elevation of CD8+CD25+ T cells in corneas of ocularly infected mice

(2010) Sariah J. Allen et al.   VIROLOGY

Developing an asymptomatic mucosal herpes vaccine: the present and the future

(2009) Gargi Dasgupta et al.   Future Microbiology

CCL3 protects mice from corneal pathology during recurrent HSV-1 infection

(2008) Patrick et al.   Frontiers in Bioscience-Landmark

Asymptomatic Human CD4+ Cytotoxic T-Cell Epitopes Identified from Herpes Simplex Virus Glycoprotein B

(2008) A. A. Chentoufi et al.   JOURNAL OF VIROLOGY

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE

Interferon gamma is not required for recurrent herpetic stromal keratitis

(2008) Tammie L. Keadle et al.   VIROLOGY

Ocular HSV-1 Latency, Reactivation and Recurrent Disease

(2008) Hassanain S. Toma et al.   Seminars in Ophthalmology