Article
Chemistry, Inorganic & Nuclear
Chao Zhang, Xusheng Guo, Xuwen Da, Zhanhua Wang, Xuesong Wang, Qianxiong Zhou
Summary: The Ru1 compound designed in this study exhibits multiple anticancer mechanisms and significantly enhanced photocytotoxicity under 600 nm light irradiation, making it a promising candidate for photodynamic therapy and photoactivated chemotherapy.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Lukas Siebenmann, Robin Bolliger, Henrik Braband, Olivier Blacque, Roger Alberto
Summary: In this study, the arene substitution reactions of manganese were investigated and benzene substitution was achieved by altering the hapticity of coordinated benzene. Mechanistic elucidation of these reactions was carried out through NMR studies, isolation of reaction intermediates, and comprehensive characterizations. The results highlight the significant reactivity and mechanistic insights of these reactions.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Jia-Ahn Pan, Justin C. Ondry, Dmitri Talapin
Summary: A direct photopatterning approach for lead halide perovskite nanocrystals has been introduced, allowing for the creation of patterns through molecular cleavage after photoirradiation. Postpatterning ligand exchange results in increased photoluminescence quantum yields and emission wavelength tunability. The patterned nanocrystal films exhibit photoconductive behavior, indicating good electrical contact between the nanocrystals.
Article
Chemistry, Multidisciplinary
Martin L. Kirk, David A. Shultz, Patrick Hewitt, Ju Chen, Art van der Est
Summary: Photoinduced electron spin polarization (ESP) in the ground state of luminescent materials is investigated, and the phenomenon is found to be influenced by the connecting structure and have a relatively long duration.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Multidisciplinary Sciences
Pritam Sadhukhan, Shu-Qi Wu, Shinji Kanegawa, Sheng-Qun Su, Xiaopeng Zhang, Takumi Nakanishi, Jeremy Ian Long, Kaige Gao, Rintaro Shimada, Hajime Okajima, Akira Sakamoto, Joy G. Chiappella, Myron S. Huzan, Thomas Kroll, Dimosthenis Sokaras, Michael L. Baker, Osamu Sato
Summary: Energy harvesting by utilizing optical control has emerged as a promising solution to alleviate energy and environmental crisis. However, it is challenging to realize nano-scale energy storage and conversion in the same material. Here the authors report a nonferroelectric molecular [CoGa] crystal that uses light as an external stimulus to exhibit photoenergy conversion and energy storage properties.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Morris E. Olumba, Hanah Na, Alan E. Friedman, Thomas S. Teets
Summary: In this study, a facile [4 + 4] coordination-driven self-assembly of cyclometalated iridium(III) using linear aryldiisocyanide bridging ligands (BLs) is demonstrated. A family of nine new [Ir(C^N)2(μ-BL)](4)(4+) coordination cages was prepared with isolated yields of 40-83%, and detailed photophysical studies revealed the nature of the luminescent triplet states in these complexes. This work illustrates that aromatic diisocyanide ligands enable coordination-driven assembly of inert iridium(III) nodes under mild conditions, producing supramolecular coordination complexes with desirable photophysical properties.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Gina Elena Giacomazzo, Luca Conti, Annalisa Guerri, Marco Pagliai, Camilla Fagorzi, Patrick Severin Sfragano, Ilaria Palchetti, Giangaetano Pietraperzia, Alessio Mengoni, Barbara Valtancoli, Claudia Giorgi
Summary: This study successfully tuned the mode of action of nitroimidazole derivatives by synthesizing different architectures of ruthenium complexes, and improved their antibacterial activity upon light exposure. This is of significant importance for the design of novel antimicrobials and their application in biologically relevant environments.
INORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Emanuele Zanda, Natalia Busto, Lorenzo Biancalana, Stefano Zacchini, Tarita Biver, Begona Garcia, Fabio Marchetti
Summary: The study found that certain ruthenium complexes exhibited remarkable stability in water and cell culture medium, showing strong cytotoxicity against cancer cell lines, with RUCYN being the most promising one with significant selectivity compared to non-cancerous cells. The variability of affinity of the complexes for BSA and DNA binding was determined, with certain complexes showing enhanced cell internalization and cytotoxicity at the expense of selectivity.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Biochemistry & Molecular Biology
Xia Hu, Ning-Yi Liu, Yuan-Qing Deng, Shan Wang, Ting Liu, Xue-Wen Liu
Summary: The study found that the two new phenanthroline-based ligand ruthenium complexes show good performance in interacting with DNA, with complex 2 demonstrating higher DNA affinity and photocleavage activity. The complexes showed no toxicity towards tumor cells in the dark, but demonstrated obvious photocytotoxicities, with complex 2 exhibiting large phototherapeutic indices towards HeLa cells. These complexes may act as DNA intercalators, DNA photocleavers, and photocytotoxic agents.
Article
Chemistry, Multidisciplinary
George S. Biggs, Oskar James Klein, Sarah L. Maslen, J. Mark Skehel, Trevor J. Rutherford, Stefan M. V. Freund, Florian Hollfelder, Sally R. Boss, Paul D. Barker
Summary: The study focuses on generating artificial metalloenzymes through ligand exchange, with a fast and robust procedure developed using Ru-II(eta(6)-arene)(bipyridine) complexes. By successfully introducing metal cofactors into proteins to generate catalysts, the research demonstrates a significant increase in catalytic activity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Inorganic & Nuclear
Nilmadhab Roy, Utsav Sen, Prithvi Moharana, Lavanya Thilak Babu, Binoy Kar, Seshu Vardhan, Suban K. Sahoo, Bipasha Bose, Priyankar Paira
Summary: By synthesizing 2,2'-bipyrimidine-based complexes, LRuIr was found to exhibit inhibitory effects on both MDA-MB-468 and Caco-2 cells, with apoptotic events occurring in MDA-MB-468 cancer cells through cell cycle arrest.
DALTON TRANSACTIONS
(2021)
Article
Biochemistry & Molecular Biology
Maomao He, Ran Wang, Peiyuan Wan, Hexiang Wang, Yi Cheng, Pengcheng Miao, Zhiyong Wei, Xuefei Leng, Yang Li, Jianjun Du, Jiangli Fan, Wen Sun, Xiaojun Peng
Summary: A biodegradable Ru-containing polymer with high drug loading capacity has been developed for effective release of anticancer drug and inhibition of tumor growth under light stimulation. The method shows good biocompatibility and opens up opportunities for multi-therapeutic agent delivery and enhanced phototherapy.
Article
Chemistry, Inorganic & Nuclear
Rain Ng, Man-Chun Chong, Wai-Man Cheung, Herman H-Y Sung, Ian D. Williams, Wa-Hung Leung
Summary: Heterometallic mu-nitrido complexes have been synthesized from organometallic complexes containing O/S-donor ligands and a ruthenium(VI) nitride. The bonding in these complexes is described as double bond character of the Ir-N-(nitride) bonds. The reactions of these complexes with other ligands and reagents were also studied.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Yuliang Yang, Ya Gao, Yanyan Sun, Jian Zhao, Shaohua Gou
Summary: A series of novel ruthenium(II) and iridium(III) complexes with different ancillary ligands and a PARP-1-inhibitory chelating ligand were designed and synthesized. The complexes exhibited potent antiproliferative activity on cancer cell lines, with the ruthenium(II) complexes being more cytotoxic. The most active ruthenium complex induced apoptosis in cancer cells through multiple mechanisms.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Yan Lei, Ruijuan Qi, Jinpeng Wu, Haodan Guo, Xiangrong Li, Yanyan Fang, Dongmei Xie, Yuan Lin
Summary: The surface of InZnP CQDs has been reconstructed with PbS via a chemical engineering strategy, leading to significantly enhanced photoinduced charge carrier transfer and the performance of solid state solar cells.
JOURNAL OF POWER SOURCES
(2022)
Article
Chemistry, Inorganic & Nuclear
Angela Lis, Viorica Gladchi, Gheorghe Duca, Sergey Travin
Summary: This work presents studies on the photochemical transformations of TU and Cys with the addition of Cu(II) or Fe(III) ions. The results show that the oxidation rate of the thiols increases significantly when Cu(II) or Fe(III) ions are added to the system. It has also been found that TU and Cys can form stable complex compounds with the studied metal ions. The oxidation rates of the thiols are found to depend on the radiation intensity and emission spectrum of the irradiation sources.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Cristiane F. A. Teixeira, Estefane I. Teixeira, J. P. C. Nascimento, M. Amilcar Junior, L. M. C. Pinto, Anderson R. L. Caires, G. B. Alcantara, Ana C. Micheletti, Victor M. Deflon, Davi F. Back, Heveline Silva, Lucas Pizzuti, Gleison Antonio Casagrande
Summary: Novel binuclear heteroleptic copper(I) complexes based on mixed DPPE/thiocarbamoyl-pyrazoline ligands were synthesized and structurally characterized. These complexes exhibited similar structural behavior around the Copper(I) atoms and showed promising antimicrobial and anticancer activities.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Chen Chen, Li Liu, Xin-Xin Zhong, Fa-Bao Li, Hai-Mei Qin
Summary: Thermally activated delayed fluorescent (TADF) Cu(I) halide complexes with short lifetimes and intense emissions were synthesized and characterized. These complexes exhibit intense green to yellow-green delayed fluorescence and are suitable for OLED devices.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Tian-Yu Zhang, Xue-Qian Wu, Heng-Yu Ruan, Yi Yuan, Le Wang, Ya-Pan Wu, Qing-Wen Han, Ruan Chi, Dong-Sheng Li
Summary: In this study, a novel Ni(II)-based metal-organic framework with good electrocatalytic oxidation performance was successfully synthesized, showing potential for direct alcohol fuel cells.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Susanta Das Baishnab, R. N. Dutta Purkayastha, Waldemar Maniukiewicz, Rosa M. Gomila, Antonio Frontera
Summary: The synthesis, structure, and DNA binding ability of three decavanadate complexes containing cationic organic moieties were reported. The complexes were characterized by various techniques and their solid-state structures were analyzed. The complexes showed interesting assembly patterns and exhibited moderately strong intercalative binding with CTDNA. Additionally, their micellization behavior in the presence of the surfactant CTAB was studied.
INORGANICA CHIMICA ACTA
(2024)
Review
Chemistry, Inorganic & Nuclear
Jubaraj B. Baruah
Summary: Isomorphous series are generated by replacing atoms or molecules to form materials with similar compositions. They allow modulation of structure and properties, and generate equivalent compositions with novel material properties. The study of stereo-electronic aspects of different equivalent compositions can improve the utility of the original composition.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Kamelah S. Al-Rashdi, Bandar A. Babgi, Ehab M. M. Ali, Bambar Davaasuren, Abdul-Hamid M. Emwas, Mariusz Jaremko, Mark G. Humphrey, Mostafa A. Hussien
Summary: Tridentate ligands were used to synthesize a set of palladium complexes, which were characterized and found to have DNA and BSA binding abilities. The complexes also showed differences in anticancer activities.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Diane Isaacs, Chandler Cox, Mark A. Bezpalko, W. Scott Kassel, William G. Dougherty
Summary: The structure and electrochemical properties of zinc(II) complexes with a face-capping ligand have been investigated, revealing the effect of the ligand on bound semiquinonate (SQ) radicals. The substitution pattern of the SQ ring plays a crucial role in determining the fate of the bound SQ radicals. Additionally, the protective pocket formed by the ligand's phenyl substituents is unable to prevent decomposition of SQ radicals with minimal steric bulk, suggesting that substitution of the SQ ring is the main contributor to their stabilization.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Xingliang Chen, Zhiqiang Jiang
Summary: Here, a series of zinc tetrahedral tetrazolate frameworks (Zn-TTFs) are presented, and it is demonstrated that rotation of carboxyl group can generate structural diversity. Compound 3 exhibits a unique zeolite-like structure, while compound 4 shows both super acid and alkali resistance.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Ankita Puri, Allison Mcaninch, Sheng Shu, Khashayar Rajabimoghadam, Maxime A. Siegler, Marcel Swart, Isaac Garcia-Bosch
Summary: In this article, the synthesis and characterization of copper, nickel, and palladium complexes bound by bidentate ligands derived from ortho-phenylenediamine are described. The complexes contain tunable H-bond donors and their crystal structures reveal intramolecular H-bonding interactions between the ligand scaffolds. Variations in the coordination sphere led to the isolation of the complexes in square-planar or twisted pseudo-tetrahedral geometries. Structural analysis showed that intramolecular H-bonding interactions can be altered by disrupting the bonds between countercations, solvent of crystallization, and ligand scaffold, resulting in changes in the geometry of the complexes. DFT calculations confirmed that Cu complexes prefer twisted geometries while Ni and Pd complexes favor square-planar geometries.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Laiane dos Santos Oliveira, Pedro Henrique de Souza Guarda, Leticia Bazilio Rosa, Gustavo Clauss Rodrigues, Daniele Daiane Affonso, Joao Ernesto de Carvalho, Igor Andrade Santos, Mark Harris, Douglas Hideki Nakahata, Jose Ricardo Sabino, Danilo Ciccone Miguel, Ana Lucia Tasca Gois Ruiz, Ana Carolina Gomes Jardim, Camilla Abbehausen
Summary: Chalcones are chemical precursors of flavonoids that have various biological properties. In this study, novel copper(II)-2'-hydroxy-4-benzyloxychalcone complexes were synthesized and evaluated for their antileishmanial, antiproliferative, and antiviral activities. The results demonstrated that these complexes showed potential effects against tumor cells, leishmania parasites, and SARS-CoV-2 virus. The study also highlighted the influence of ligand structure on biological activity.
INORGANICA CHIMICA ACTA
(2024)
Review
Chemistry, Inorganic & Nuclear
Archana Thakur, Harpreet Kaur, Vishal Tyagi
Summary: This review article discusses the findings of research on the 13C NMR spectra of di- and tri-butyltin carboxylates, highlighting the importance of 13C NMR chemical shifts in determining the chemical surroundings of carbon nuclei and their role in structure elucidation.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Qiang Zhao, Qi-Yang Li, Zhi Shen, Guo Zang, Wen-Jun Lv
Summary: In this study, five metal complexes were synthesized using a solvothermal reaction and their structures were analyzed by single crystal X-ray diffraction. Fluorescence and magnetic properties of some complexes were also investigated.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Jeremy Erb, Darcy Setter, Jake Swavey, Frederick Willits, Shawn Swavey
Summary: Three BODIPY-Ru(II) complexes were synthesized by coordinating [Ru(bpy)2Cl]+ complexes to BODIPY ligands. The spectroscopic and electrochemical properties of the complexes were characterized. The complexes exhibited intense absorption peaks due to the pi pi* transitions localized on the BODIPY core, and additional charge transfer transitions associated with the metal center. The complexes showed significant singlet oxygen generation and were able to induce photo-nicking of DNA.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Sahin Reja, Dilip Sarkar, Kaushik Sarkar, Deboshmita Mukherjee, T. K. S. Fayaz, Palash Sanphui, Rajesh Kumar Das
Summary: A promising bioinspired metallocatalyst has been produced and characterized, showing high catalytic activity in oxygen dependant enzymatic radical pathway. The catalyst also exhibits inter and intra molecular H-bonding and C-H-pi interactions.
INORGANICA CHIMICA ACTA
(2024)