High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles

Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation

(2016) Sivapriya Kailasan Vanaja et al.   CELL

Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity

(2015) Jieling Yang et al.   CURRENT OPINION IN IMMUNOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Purified monomeric ligand.MD-2 complexes reveal molecular and structural requirements for activation and antagonism of TLR4 by Gram-negative bacterial endotoxins

(2014) Theresa L. Gioannini et al.   IMMUNOLOGIC RESEARCH

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

(2014) D. M. Pilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic labeling to characterize the overall composition of Francisella lipid A and LPS grown in broth and in human phagocytes

(2013) Jason H Barker et al.   Innate Immunity

Modulating the innate immune response by combinatorial engineering of endotoxin

(2013) Brittany D. Needham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Caspase-11 Protects Against Bacteria That Escape the Vacuole

(2013) Y. Aachoui et al.   SCIENCE

NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

(2012) Liping Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

(2011) Gregory A Esparza et al.   Innate Immunity

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Morphology, size distribution, and aggregate structure of lipopolysaccharide and lipid A dispersions from enterobacterial origin

(2010) Walter Richter et al.   Innate Immunity

The BPI/LBP family of proteins: A structural analysis of conserved regions

(2010) Lesa J. Beamer et al.   PROTEIN SCIENCE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Wall Teichoic Acid Deficiency in Staphylococcus aureus Confers Selective Resistance to Mammalian Group IIA Phospholipase A2 and Human  -Defensin 3

(2008) T. Koprivnjak et al.   INFECTION AND IMMUNITY

Isolation of Monomeric and Dimeric Secreted MD-2

(2008) Athmane Teghanemt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY