Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis

(2016) Carlo De Salvo et al.   AMERICAN JOURNAL OF PATHOLOGY

Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-induced inflammatory tumor necrosis factor-α, contributing to epithelial barrier dysfunction

(2015) Imtiyaz Thagia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Association of TLR5 Gene Polymorphisms in Ulcerative Colitis Patients of North India and Their Role in Cytokine Homeostasis

(2015) Naresh Kumar Meena et al.   PLoS One

Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort

(2015) Steffen Bank et al.   PLoS One

Intestinal Epithelial Cell Toll-like Receptor 5 Regulates the Intestinal Microbiota to Prevent Low-Grade Inflammation and Metabolic Syndrome in Mice

(2014) Benoit Chassaing et al.   GASTROENTEROLOGY

The microbiota and inflammatory bowel disease: Insights from animal models

(2013) Joanna M. Peloquin et al.   ANAEROBE

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation

(2013) D. Corridoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Central Role of the Gut Epithelial Barrier in the Pathogenesis of Chronic Intestinal Inflammation: Lessons Learned from Animal Models and Human Genetics

(2013) Luca Pastorelli et al.   Frontiers in Immunology

New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation

(2012) Giorgos Bamias et al.   CYTOKINE

Interleukin 23 Production by Intestinal CD103+CD11b+ Dendritic Cells in Response to Bacterial Flagellin Enhances Mucosal Innate Immune Defense

(2012) Melissa A. Kinnebrew et al.   IMMUNITY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Probiotic Bacteria Regulate Intestinal Epithelial Permeability in Experimental Ileitis by a TNF-Dependent Mechanism

(2012) Daniele Corridoni et al.   PLoS One

Microbiota, Disease, and Back to Health: A Metastable Journey

(2012) R. Blumberg et al.   Science Translational Medicine

SAMP1/YitFc mouse strain: A spontaneous model of Crohnʼs disease-like ileitis

(2011) Theresa T. Pizarro et al.   INFLAMMATORY BOWEL DISEASES

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

(2010) R. DUCHMANN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Induction of Colitis and Ileitis in Mice Is Associated with Marked Increases in Intestinal Concentrations of Stimulants of TLRs 2, 4, and 5

(2010) Clett Erridge et al.   PLoS One

Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis

(2010) Luca Pastorelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Tight Junction Dysregulation in the SAMP1/YitFc Model of Crohn's Disease-like Ileitis

(2009) Brian K. Reuter et al.   Annals of the New York Academy of Sciences

Novel model of TH2-polarized chronic ileitis: The SAMP1 mouse

(2009) Eoin N. McNamee et al.   INFLAMMATORY BOWEL DISEASES

Increased Immune Reactivity Predicts Aggressive Complicating Crohn's Disease in Children

(2008) Marla C. Dubinsky et al.   Clinical Gastroenterology and Hepatology

An Antibiotic-Responsive Mouse Model of Fulminant Ulcerative Colitis

(2008) Silvia S Kang et al.   PLOS MEDICINE