Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice

NDP-α-MSH induces intense neurogenesis and cognitive recovery in Alzheimer transgenic mice through activation of melanocortin MC4 receptors

(2015) Daniela Giuliani et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A Dual Inhibitor of Cyclooxygenase and 5-Lipoxygenase Protects Against Kainic Acid-Induced Brain Injury

(2015) Letteria Minutoli et al.   NEUROMOLECULAR MEDICINE

The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

(2015) Angélica Maria Sabogal-Guáqueta et al.   NEUROPHARMACOLOGY

A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy

(2014) Laura Caberlotto et al.   BMC Systems Biology

Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions

(2014) Alessandra Bitto et al.   MEDIATORS OF INFLAMMATION

Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer’s disease

(2013) Sathish Kumar et al.   ACTA NEUROPATHOLOGICA

Sustained Interleukin-1  Overexpression Exacerbates Tau Pathology Despite Reduced Amyloid Burden in an Alzheimer's Mouse Model

(2013) S. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Immunotherapy against amyloid pathology in Alzheimer's disease

(2013) Daniela Galimberti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The NLRP3 Inflammasome in Alzheimer’s Disease

(2013) Meng-Shan Tan et al.   MOLECULAR NEUROBIOLOGY

Melanocortins protect against progression of Alzheimer's disease in triple-transgenic mice by targeting multiple pathophysiological pathways

(2013) Daniela Giuliani et al.   NEUROBIOLOGY OF AGING

Intra-Hippocampal Transplantation of Neural Precursor Cells with Transgenic Over-Expression of IL-1 Receptor Antagonist Rescues Memory and Neurogenesis Impairments in an Alzheimer’s Disease Model

(2013) Ofra Ben-Menachem-Zidon et al.   NEUROPSYCHOPHARMACOLOGY

Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels

(2013) Anna M. Lilja et al.   PLoS One

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition

(2012) Paramita Chakrabarty et al.   Molecular Neurodegeneration

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Mitochondrial ROS fuel the inflammasome

(2011) Matthew T Sorbara et al.   CELL RESEARCH

Cost of disorders of the brain in Europe 2010

(2011) Anders Gustavsson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), and 5-Lipoxygenase, Modifies COX-2 Gene Expression, and Acts as an Antioxidant

(2011) Bruce P. Burnett et al.   MEDIATORS OF INFLAMMATION

Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Aβ aggregation in SH-SY5Y cells

(2011) Fei Yin et al.   NEUROSCIENCE LETTERS

Pharmacotherapies for Alzheimer's disease: Beyond cholinesterase inhibitors

(2011) Haythum O. Tayeb et al.   PHARMACOLOGY & THERAPEUTICS

EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP

(2010) Jamie Winderbaum Fernandez et al.   FEBS LETTERS

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications

(2010) Rebecca Banerjee et al.   TRENDS IN NEUROSCIENCES

Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268

(2009) Daniela Giuliani et al.   BRAIN BEHAVIOR AND IMMUNITY

Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

(2009) Lenka Munoz et al.   NEUROPHARMACOLOGY

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

(2008) Linda A. Kotilinek et al.   BRAIN

Cyclooxygenase-2 in Synaptic Signaling

(2008) Hongwei Yang et al.   CURRENT PHARMACEUTICAL DESIGN

5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer’s disease

(2007) Omidreza Firuzi et al.   FASEB JOURNAL