Article
Chemistry, Applied
Xiaonan Duan, Xuepeng Wang, Xingkun Chen, Jisong Zhang
Summary: A continuous flow system based on a micropacked bed reactor was developed for the selective hydrogenation of heterocyclic nitroaromatics, achieving high yields in model reactions and exceeding 97.5% in all relevant nitroaromatic reductions. Compared with batch reactors, the continuous flow system enables efficient hydrogenation of nitroaromatics with shorter reaction times and safer operation.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2021)
Article
Engineering, Chemical
Chi Ma, Mengmeng Huang, Jiabin Yin, Fengyan Lou, Jisong Zhang
Summary: A slurry circulation method for coating nickel foam supports with small pore size is proposed to prepare monolithic catalysts for micropacked beds. The method is demonstrated to be universal and applicable for various supports, resulting in uniform coatings with predictable weight. The monolithic catalysts prepared by this method exhibit high activity, long-term stability, and mechanical stability in the hydrogenation reaction of alpha-methylstyrene.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Yang Si, Song Liu, Weixing Ming, Wei Wei, Lu Ji, JianJun Zhang, Tingwang An, Dangsheng Gong, Jingnan Zhao, Qingwei Meng, Dongmao Yan
Summary: Due to the complexity of the hydrogenation process of aromatic dinitro compounds, using a micropacked-bed reactor in a continuous flow system can improve the conversion rate and selectivity. In this study, the hydrogenation of 2,4-dinitroanisole was used as a model reaction, and different catalysts were tested in a continuous flow system. The experiment achieved high conversion, high selectivity, and good durability.
Article
Chemistry, Multidisciplinary
Zhou Lan, Yangcheng Lu
Summary: The successful matching of micro-dispersion state and reaction kinetics in the nitration reaction process was achieved in this study, allowing for fast and efficient reactions. By utilizing adiabatic conditions, a micropacked-bed reactor, and partial product circulation, the synthesis of 3,4-dichloronitrobenzene from o-dichlorobenzene was completed within 5 seconds with over 89% selectivity.
JOURNAL OF FLOW CHEMISTRY
(2021)
Article
Engineering, Chemical
Jiangshan Liu, Jesse Zhu
Summary: The reactor performance of bubbling fluidized bed (BFB) and turbulent fluidized bed (TFB) were carefully examined and compared, with TFB showing better performance due to its higher conversion and homogeneous gas-solids mixing. The flow structures essentially dictate the reactor performance in the low-velocity fluidized beds.
Article
Energy & Fuels
Mehrdad Ghasabehi, Moosa Ashrafi, Mehrzad Shams
Summary: The study introduces a novel parallel flow field design to enhance the electrochemical performance and reduce the parasitic power loss of proton exchange membrane fuel cells. By comparing different structures and utilizing techniques such as tapered main channels and manipulating manifolds, the best flow field design is determined, with increasing cathode stoichiometry identified as the most effective factor in enhancing power density.
Article
Chemistry, Multidisciplinary
Xiaonan Duan, Jiabin Yin, Aoxing Feng, Mengmeng Huang, Weisong Fu, Wanfu Xu, Zhenfu Huang, Jisong Zhang
Summary: A H-flow system was developed for the selective hydrogenation of halogenated nitroaromatic compounds, showing high yield and reduced dehalogenation effects.
JOURNAL OF FLOW CHEMISTRY
(2022)
Article
Engineering, Environmental
Chien-Ping Wang, Yong-kun Pan, Ming-Han Li
Summary: A novel planar water disinfection reactor with parallel-channel configurations is proposed to enhance the efficiency of water sterilization. The experimental results show that the reactor with four channels achieves the highest inactivation efficiency due to high flow uniformity, sufficient exposure time, and elimination of circulation. Increasing the number of channels and baffle width can improve the disinfection efficiency.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Yang Si, Weixing Ming, Song Liu, Wei Wei, Lu Ji, Dangsheng Gong, Jing Wang, Cuncun Zuo, Haofei Huang, Dongmao Yan
Summary: In this study, a continuous selective catalysis of 4-(Trifluoromethoxy)aniline, a key intermediate in the preparation of riluzole, was conducted using a micropacked-bed reactor packed with Pt/BAC catalysts. The continuous hydrogenation process showed higher efficiency, selectivity, and safety with less energy consumption compared to the traditional batch reduction process.
Article
Engineering, Chemical
Chi Ma, Le Sang, Xiaonan Duan, Jiabin Yin, Jisong Zhang
Summary: This study compared and screened methods of coating Al2O3 on nickel micro-foam to prepare monolithic catalyst coatings. Optimal slurry circulation at 162 ml.min(-1) was found, and changing pretreatment conditions can control the pore size on the substrate surface. An empirical correlation for predicting pore size was proposed, and the adhesion of coatings with substrate pretreatment was significantly better than without.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2021)
Article
Environmental Sciences
Asfak Patel, Arvind Kumar Mungray, Alka Mungray
Summary: A novel Vertical Up-Flow Forward Osmosis (VUF-FO) reactor was designed and evaluated to improve the performance of the FO process. By optimizing the contacting patterns of feed and draw agent and using pulsating inlets for recirculation, the VUF-FO reactor showed a more consistent water flux and reduced reverse salt flux compared to the basic H-shape reactor. This design led to less decline in water flux and reverse salt flux, improving the overall performance of FO.
Article
Engineering, Environmental
Mei Yang, Lina Yang, Jia Zheng, Nicole Hondow, Richard A. Bourne, Tom Bailey, George Irons, Elliot Sutherland, Daniela Lavric, Ke-Jun Wu
Summary: The study conducted continuous synthesis of Ag nanoparticles using the Corning Advanced-Flow Reactor (AFR) and optimized mixing characteristics by controlling flow rate ratio and total flow rate, finding significant effects on the average particle size and particle size distribution of Ag NPs.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biochemical Research Methods
Matteo Antognoli, Daniel Stoecklein, Chiara Galletti, Elisabetta Brunazzi, Dino Di Carlo
Summary: This study optimized mixing efficiency by analyzing sequences of cylindrical obstacles in the inertial regime, predicted and optimized interfacial stretching of co-flowing fluids using a specialized software, and tested new passive mixer designs using confocal microscopy and CFD simulations, achieving mixing efficiencies around 80%.
Article
Engineering, Chemical
Xin Liu, Zhujun Zou, Dong Wang, Dongyu Du, Zhuo Li, Weiyi Li
Summary: The key to sustainable development of membrane technology is the green fabrication of biopolymer membranes. This study focuses on fabricating chitosan membranes via wet precipitation and optimizing their filtration performance. By using pure ethanol as the coagulant at a subzero temperature, a laminated substructure is formed which enhances water permeance without decreasing the rejection of micron-sized particles and macromolecules. Optical coherence tomography is also used to characterize the film formation and understand the effects of coagulating conditions on membrane characteristics.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Mathematics
Mai The Vu, Khalid A. Alattas, Yassine Bouteraa, Reza Rahmani, Afef Fekih, Saleh Mobayen, Wudhichai Assawinchaichote
Summary: This paper proposes an optimal fuzzy enhanced sliding mode control approach for a Stewart parallel robot platform, which achieves optimum performance and minimum control effort by designing a table of rules for the fuzzy system to provide the required coefficients of the sliding mode controller. The proposed approach reduces chattering and effectively responds to control energy demands, while preventing actuator saturation.
Article
Nanoscience & Nanotechnology
Hirotada Hirama, Satoshi Wada, Jiro Shimamura, Yusuke Komazaki, Tomoya Inoue, Toru Torii
MICROFLUIDICS AND NANOFLUIDICS
(2017)
Article
Biotechnology & Applied Microbiology
Hirotada Hirama, Taku Satoh, Shinji Sugiura, Kazumi Shin, Reiko Onuki-Nagasaki, Toshiyuki Kanamori, Tomoya Inoue
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
(2019)
Article
Chemistry, Multidisciplinary
Hirotada Hirama, Yusuke Sugiura, Yusuke Komazaki, Tom Torii
Article
Chemistry, Multidisciplinary
Hirotada Hirama, Takahiro Iida, Yusuke Komazaki, Torn Torii, Harutaka Mekaru
Article
Chemistry, Multidisciplinary
Hirotada Hirama, Satoshi Yoshii, Yusuke Komazaki, Shinya Kano, Toru Torii, Harutaka Mekaru
Summary: The digital microfluidic device with downward electrodes allows for droplet manipulation, including transportation, dispensing, and coalescence, without technical constraints. It is expected to be useful for droplet-based multi-content screening and high-throughput screening in the analysis and synthesis field.
Article
Chemistry, Analytical
Hirotada Hirama, Ryutaro Otahara, Shinya Kano, Masanori Hayase, Harutaka Mekaru
Summary: Nanoparticles, including exosomes, are widely used in medicinal applications and can be handled effectively using PDMS-based microchannels. The adsorption of nanoparticles on PDMS substrates and microchannels is influenced by electrostatic interactions, as demonstrated by atomic force microscopy studies. By understanding the electrostatic interactions between nanoparticles and microchannels, preconcentration, separation, and sensing of nanoparticles can be improved in PDMS-based microfluidic devices.
Article
Chemistry, Multidisciplinary
Yusuke Komazaki, Hirotada Hirama, Sei Uemura, Kiyomi Fuchigami, Toru Torii
Summary: This study presents a rapid prototyping method for droplet generators using pipette tips and glass capillaries, showing high reproducibility and controllability with less than 5% variation in droplet size among different devices. Bead encapsulation using the developed PiT-CMD device is also successfully demonstrated.
Article
Polymer Science
Hirotada Hirama, Ryutaro Otahara, Katsuo Mogi, Masanori Hayase, Toru Torii, Harutaka Mekaru
Summary: A rapid prototyping method for nanoparticle concentrators (NPCs) using hydrogel molding was developed, successfully fabricating NPCs with both straight and branched channels. The generation of ion concentration polarization (ICP) was verified, and NP concentration tests using charged NPs showed promising results, indicating the effectiveness and potential of this method for liquid biopsy and analysis applications.
Article
Chemistry, Multidisciplinary
Yusuke Komazaki, Kenji Kanazawa, Taiki Nobeshima, Hirotada Hirama, Yuichi Watanabe, Kouji Suemori, Sei Uemura
Summary: In this study, a hygroelectric cell that generates electricity based on humidity variations was modeled and the power generated by the cell was predicted through simulations. The simulation results, which took into account the water activity-dependent evaporation and condensation rates of water, as well as the water permeability of the ion-exchange membrane, were consistent with experimental results.
Article
Physics, Applied
Yusuke Komazaki, Taiki Nobeshima, Hirotada Hirama, Yuichi Watanabe, Kouji Suemori, Sei Uemura
Summary: In this study, the voltage and power output of a hygroelectric cell (HEC) were enhanced by suppressing self-discharge through the addition of polyethylene glycol (PEG) in the electrolyte solution. The addition of 2 wt% PEG4000 increased the peak-to-peak voltage from 48 mV to 128 mV under humidity changes between 30% and 90%RH, while the addition of 5 wt% PEG4000 improved the output power from 4.4 mu W to 36.7 mu W (6.4 mu W cm(-2)). The effectiveness of PEG addition was also demonstrated in an outdoor environment.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2023)
Article
Materials Science, Multidisciplinary
Hirotada Hirama, Yuya Ishikura, Shinya Kano, Masanori Hayase, Harutaka Mekaru
Summary: This study introduced a new method for preparing monodispersed polymer microcapsules, which were successfully applied in transdermal drug delivery systems. These microcapsules demonstrated good water solubility and stability, releasing drugs in the skin over time.
MATERIALS ADVANCES
(2021)
Article
Chemistry, Physical
Yusuke Komazaki, Kenji Kanazawa, Taiki Nobeshima, Hirotada Hirama, Yuichi Watanabe, Kouji Suemori, Sei Uemura
Summary: A novel type of hygroelectric generator called hygroelectric cell (HEC) was developed in this study, which can generate high current output and store energy by utilizing ambient moisture. The HEC could produce a peak-to-peak voltage of 42 mV and a short-circuit current of 5 mA at maximum humidity variation between 30-90% RH, demonstrating its potential for energy harvesting applications.
SUSTAINABLE ENERGY & FUELS
(2021)
Article
Chemistry, Multidisciplinary
Hirotada Hirama, Tomoya Inoue
Article
Physics, Applied
Y. Komazaki, H. Hirama, T. Torii
JOURNAL OF APPLIED PHYSICS
(2015)