Article
Dentistry, Oral Surgery & Medicine
Myong Ji Kim, Jae-Kook Cha, Kyeong-Won Paeng, Young Woo Song, Daniel S. Thoma, Ronald E. Jung, Ui-Won Jung
Summary: The study compared the healing patterns between immediate and delayed applications of BMP-2 in damaged extraction sockets in dogs. The results showed that delayed application of BMP-2 2 weeks after surgery did not provide any advantage over immediate application in terms of new bone formation, despite observing larger bone formation area in the control group.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Immunology
Duchenhui Li, Xiao Li, Jie Zhang, Zhenglong Tang, Ai Tian
Summary: This study found that IL-4 injection can promote bone regeneration at the site of bone defects in aged rats by reducing inflammation and regulating macrophage polarization.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Infectious Diseases
Glauco Chisci, Luca Fredianelli
Summary: This study investigates the potential use of oral bromelain in alveolar ridge preservation. The results show that patients who used bromelain had significantly lower inflammation, swelling, and Visual Analogue Scale scores after surgery compared to those who used a placebo.
Review
Chemistry, Multidisciplinary
Xu Xue, Yan Hu, Yonghui Deng, Jiacan Su
Summary: Hydrogels are promising candidates for bone tissue engineering due to their unique 3D network structure. Injectable hydrogels based on biocompatible materials offer advantages in minimally invasive surgery and drug delivery. Advanced approaches and innovative ideas of bioactive hydrogels are expected to enhance the quality of life for patients with bone injuries.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Zhiwei Cao, Haitao Shi, Liru Hu, Kun Zhang, Xiaohui Zhang, Jian Pan
Summary: YAP promotes bone formation, cell proliferation, and reduces adipogenic differentiation and apoptosis during the middle to late stages of tooth extraction socket healing.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Polymer Science
Janhavi Sonatkar, Balasubramanian Kandasubramanian
Summary: Bioactive glasses have been traditionally used for permeating and repairing bone defects, with 45S5 Bio glass being a prime artificial material developed by Larry Hench. These materials have exceptional biocompatibility and can form a HA coat in the body. Various synthesis techniques have been developed for bioactive glasses containing biocompatible polymers, aiming to review the modern evolution of glass for bone regeneration. These glasses can connect to osseous matter and restore new bone growth over time, ultimately restoring the ailing or defective bone to its original condition and function.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Medicine, General & Internal
Ugo Covani, Enrica Giammarinaro, Daniele Panetta, Piero A. Salvadori, Saverio Cosola, Simone Marconcini
Summary: The study evaluated alveolar bone remodeling after tooth extraction in a rabbit model, with or without the use of a collagen plug, through micro-computed tomography. It found that sockets treated with the collagen plug showed significantly less dimensional resorption compared to the natural-healing group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Physical
Marco Mozzati, Margherita Tumedei, Giorgia Gallesio, Giulio Menicucci, Carlo Manzella, Tiziano Testori, Massimo Del Fabbro
Summary: This study evaluated the effectiveness of CGFs in enhancing the healing process and reducing postoperative pain in alveolar socket. The results showed that CGFs can accelerate healing, improve the healing index, and reduce postoperative pain.
Article
Chemistry, Multidisciplinary
Sung-Wook Yoon, Young Woo Song, Ui-Won Jung, Jae-Kook Cha
Summary: This case report discusses the use of alveolar ridge preservation (ARP) technique in two cases post tooth extraction, showing that it can effectively reduce invasiveness and maintain alveolar ridge morphology based on clinical observations and radiographic analyses.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Jessica S. Martinez, Sara Peterson, Cathleen A. Hoel, Daniel J. Erno, Tony Murray, Linda Boyd, Jae-Hyuk Her, Nathan Mclean, Robert Davis, Fiona Ginty, Steven J. Duclos, Brian M. Davis, Gautam Parthasarathy
Summary: Lithography based additive manufacturing techniques, such as digital light processing (DLP), have the potential to construct complex orthopaedic implants using polymers, metals, and ceramics. In this study, hydroxyapatite (HA) coupons printed using DLP were evaluated for their biological performance in supporting cell viability, proliferation, and osteogenic differentiation. The results showed that the HA coupons had favorable characteristics for cell culture and did not impact cell behavior. The study concluded that the DLP process and LithaBone HA400 slurry are biocompatible and suitable for osteogenic applications.
Article
Chemistry, Applied
Dan Yan, Siyi Zhang, Fei Yu, Danni Gong, Jinyou Lin, Qinke Yao, Yao Fu
Summary: The study developed PLA EFMs with surface coatings of cellulose nanofibrils and silk peptide, enhancing biocompatibility and promoting conjunctival epithelial cell proliferation. The composite scaffolds loaded with levofloxacin showed excellent therapeutic effects for severe conjunctival fibrosis while reducing antibiotic use.
CARBOHYDRATE POLYMERS
(2021)
Article
Biology
Antonello Falco, Francesco Bataccia, Lorenzo Vittorini Orgeas, Federico Perfetti, Mariangela Basile, Roberta Di Pietro
Summary: This study assessed the clinical and histological healing of a post-extractive alveolus in a patient receiving oral bisphosphonates for more than 6 years, showing successful socket preservation using specific materials. The case report supports the eligibility of surgical therapy for patients undergoing oral bisphosphonate therapy, highlighting the need for more clinical studies to further support this evidence.
Review
Chemistry, Physical
Maria Pia Ferraz
Summary: This review summarizes the various materials used for bone defect replacement or repair in dentistry and oral and maxillofacial surgeries. Factors such as tissue viability, size, shape, and defect volume influence the choice of material. Autologous bone is the gold standard for bone grafting but has limitations. Alternatives include allografts, xenografts, and synthetic materials. Calcium-phosphate-based ceramics, especially hydroxyapatite, are commonly used due to their similarity to natural bone. This review aims to provide a comprehensive analysis of grafting materials in dentistry and discusses their properties, advantages, and challenges.
Article
Polymer Science
Carlos Humberto Valencia-Llano, Diego Lopez-Tenorio, Carlos David Grande-Tovar
Summary: This study compared the biological response of two commercial xenografts and a commercial collagen membrane, demonstrating their biocompatibility and potential through a series of tests.
Review
Dentistry, Oral Surgery & Medicine
Mauricio G. Araujo, Debora R. Dias, Flavia Matarazzo
Summary: Following tooth extraction, socket healing occurs with a marked reduction in ridge dimensions. The quantity and quality of socket walls influence ridge diminution. A damaged socket with fewer walls and a thin buccal bone wall negatively impact healing outcome. Periodontally compromised sockets lead to extensive dimensional changes. Angulation between tooth and basal bone, as well as basal bone dimensions, also affect socket healing. Anatomical characteristics of the alveolar process and basal bone play a role in socket healing.
PERIODONTOLOGY 2000
(2023)
Letter
Endocrinology & Metabolism
K. Onbasi, H. Hatipoglu, S. Ucgun, M. Gungor Hatipoglu
ACTA ENDOCRINOLOGICA-BUCHAREST
(2015)
Article
Medicine, General & Internal
Hasan Hatipoglu, Sibel Canbaz Kabay, Mujgan Gungor Hatipoglu, Hilmi Ozden
MEDICAL PRINCIPLES AND PRACTICE
(2016)
Article
Medicine, General & Internal
Erim Gulcan, Serdar Toker, Hasan Hatipoglu, Aynur Gulcan, Aysun Toker
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
(2008)
Article
Dentistry, Oral Surgery & Medicine
Serap Karakis Akcan, Berceste Guler, Hasan Hatipoglu
JOURNAL OF PERIODONTOLOGY
(2019)
Article
Chemistry, Physical
Berceste Guler, Ahu Uraz, Hasan Hatipoglu, Mehmet Yalim
Summary: The aim of this study was to compare the surface chemistries of two different implant surfaces in failing dental implants. The results indicated that different parts of the implants affected by peri-implant inflammation showed varying surface chemistries, but there was no significant difference between implants with different surfaces.
Article
Medicine, General & Internal
Ezgi Gurbuz, Mujgan Gungor, Hasan Hatipoglu
Summary: This study aimed to analyze the prevalence of tonsilloliths and investigate the association between tonsilloliths and dental plaque-related pathologies. The findings indicated that cases with tonsilloliths had a higher number of missing teeth and apical periodontitis compared to cases without tonsilloliths. The mean percentage of bone loss was also significantly higher in the tonsillolith group. Computed tomography studies and randomized, prospective, clinical trials are needed to confirm these associations.
MEDICAL PRINCIPLES AND PRACTICE
(2022)
Review
Clinical Neurology
Hasan Hatipoglu, Sibel Canbaz Kabay, Mujgan Gungor Hatipoglu
TURKISH JOURNAL OF NEUROLOGY
(2015)
Review
Endocrinology & Metabolism
H. Hatipoglu, F. Yaylak, Y. Gungor
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2015)
Article
Geriatrics & Gerontology
Burak Demiralp, Guliz N. Guncu, Nermin Yamalik, Hasan Hatipoglu, Erdem Karabulut, Reha Alpar, Haviye Nazliel-Erverdi
TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
(2011)
Article
Dentistry, Oral Surgery & Medicine
G. Pekkan, A. Kilicoglu, H. Hatipoglu
COMMUNITY DENTAL HEALTH
(2011)
Article
Medicine, General & Internal
Mujgan Gungor Hatipoglu, Guliz Guncu, Hasan Hatipoglu, Feriha Caglayan
JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE
(2011)
Article
Dentistry, Oral Surgery & Medicine
Hasan Hatipoglu, Faik Yaylak, Mujgan Gungor Hatipoglu
ACTA STOMATOLOGICA CROATICA
(2008)
Article
Dentistry, Oral Surgery & Medicine
Hasan Hatipoglu, Huseyin Gencay Keceli, Guliz N. Guncu, Dilek Sengun, Tolga F. Tozum
CLINICAL ORAL INVESTIGATIONS
(2007)
Article
Dentistry, Oral Surgery & Medicine
Hasan Hatipoglu, Nermin Yamalik, Atilla Berberoglu, Kenan Eratalay
JOURNAL OF PERIODONTOLOGY
(2007)
