Article
Chemistry, Analytical
Jie Xu, Ninghao Wang, Tianxiang Chu, Bingqian Yang, Xiaohua Jian, Yaoyao Cui
Summary: This paper proposes a high-frequency ultrasound imaging system based on mechanical scanning, which achieves reciprocating scanning in a range of 14 mm at a speed of 168 mm/s. The system has the characteristics of simple structure, high frequency, real-time, and good imaging performance, and can meet the clinical needs of high-resolution ultrasound images.
Article
Acoustics
Zakiullah Ali, Christian Zakian, Qian Li, Jerome Gloriod, Sophie Crozat, Francois Bouvet, Guillaume Pierre, Vassilis Sarantos, Massimiliano Di Pietro, Krzysztof Flisikowski, Peter Andersen, Wolfgang Drexler, Vasilis Ntziachristos
Summary: A 360-degree, 50 Hz frame rate scanning capsule optoacoustic endoscope for human gastrointestinal tract imaging is reported in this study. The imaging penetration depth and translational potential of the instrument were validated using an intralipid solution to simulate light scattering in human esophageal tissue and a pig esophagus.
Article
Gastroenterology & Hepatology
Bin Jiang, Yang-Yang Qian, Yuan-Chen Wang, Jun Pan, Xi Jiang, Jia-Hui Zhu, Xiao-Ou Qiu, Wei Zhou, Zhao-Shen Li, Zhuan Liao
Summary: Researchers developed a novel capsule endoscopy system for the upper and mid gastrointestinal tract using a modified detachable string magnetically controlled capsule endoscopy. The clinical application of this system demonstrated its feasibility, with successful observation of the esophagus and duodenum and high diagnostic sensitivity and safety. This alternative screening modality may be indicated for cases of suspected upper and small bowel GI bleeding.
BMC GASTROENTEROLOGY
(2023)
Article
Engineering, Electrical & Electronic
Seyed Shahim Vedaei, Khan A. Wahid
Summary: Wireless capsule endoscopy is a useful diagnostic tool for visualizing the gastrointestinal tract, but lacks location information. To address this issue, the authors propose a hybrid method called MagnetOFuse, which combines magnetic localization and low-resolution cameras to accurately localize the capsule and compensate for gastrointestinal movements.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2022)
Article
Acoustics
Boquan Wang, Yulin Zhou, Yuchen Wang, Xiaoniu Li, Liyuan He, Zhiyi Wen, Teng Cao, Lei Sun, Dawei Wu
Summary: This study proposes a new scanning method using a helical ultrasonic motor for 3-D IVUS imaging, which overcomes the challenges of existing systems that use electromagnetic motors. The ultrasonic motor is compact, lightweight, free of EMI, and shows promising application potential in mobile imaging devices. Experimental results demonstrate superior signal-to-noise ratio, rotary speed, and positioning accuracy of the proposed imaging device, with successful imaging of phantoms and porcine coronary artery.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Review
Computer Science, Information Systems
Weiyuan Chen, Jianbo Sui, Chengyong Wang
Summary: Capsule endoscopy is a non-invasive procedure that uses a wireless camera inside a capsule to capture images of the gastrointestinal tract. However, the current capsule endoscope has limitations in controllable locomotion and lacks extended functions. Magnetic actuation offers a solution to expand the capabilities of capsule endoscopy and develop multifunctional capsule robots.
Review
Medicine, General & Internal
Ji Hyung Nam, Kwang Hoon Lee, Yun Jeong Lim
Summary: Capsule endoscopy (CE) is a non-invasive diagnostic tool that allows direct visualization of the gastrointestinal tract. Initially developed for small-bowel investigation, its clinical application is expanding and there are ongoing technological advances. The future development of a mouth to anus (M2A) capsule that can investigate the entire GI tract with a single capsule is discussed in this review.
Article
Medicine, General & Internal
Yang-Chao Lin, Ching-Lin Chen, Yi-Wei Kao, Ching-Yao Tsai, Mingchih Chen, Chih-Kuang Liu
Summary: Portable magnetic-assisted capsule endoscopy (MACE) provides satisfactory patient experience and safety with comparable performance in diagnosis to conventional upper gastrointestinal endoscopy. However, it is costly and time-consuming.
Article
Nanoscience & Nanotechnology
Junxiang Cai, Yiyun Wang, Daohuai Jiang, Songsong Zhang, Yuandong Alex Gu, Liang Lou, Fei Gao, Tao Wu
Summary: This paper describes the use of an aluminum nitride (AlN) piezoelectric micromachined ultrasound transducer (PMUT) array for high-resolution photoacoustic (PA) imaging. By utilizing the high-order resonance modes of the PMUT, the imaging resolution is improved. The PMUT, based on microelectromechanical systems (MEMS), is suitable for PA endoscopic imaging of blood vessels and bronchi due to its small size and high sensitivity. The study focuses on the characterization and analysis of the PMUT's high-order resonance modes, which provide higher frequencies and wider bandwidth for PA signal detection, leading to increased resolution compared to working at the fundamental resonance mode.
MICROSYSTEMS & NANOENGINEERING
(2022)
Article
Computer Science, Artificial Intelligence
Panguluri Padmavathi, Jonnadula Harikiran
Summary: This study proposes a novel deep-learning technique to classify gastrointestinal diseases from wireless capsule endoscopy images. The method achieves high accuracy through denoising, feature extraction, and classification using optimization algorithms.
TRAITEMENT DU SIGNAL
(2023)
Article
Engineering, Electrical & Electronic
Chao Zhou, Kunpeng Qiu, Can Chen, Dengyin Zhang, Yongxin Guo
Summary: This study addresses two challenges in wireless capsule endoscopy (WCE) applications, namely the lack of high-resolution counterparts and the difficulty of utilizing temporal correlations to enhance recovery performance. A novel training dataset and an effective alignment network are proposed to tackle these challenges. Experimental results demonstrate the superiority of the proposed method in practical WCE applications over other approaches.
IEEE SENSORS JOURNAL
(2022)
Article
Automation & Control Systems
Sanghyeon Park, Hyoryong Lee, Dong-in Kim, Hyeonwoo Kee, Sukho Park
Summary: The gut microbiome plays an important role in the host organism and multiple samplings and analyses are needed to understand its relationship with the host. This article proposes an active multiple-sampling capsule that can be moved to specific locations in the gastrointestinal tract to collect gut-microbe-containing intestinal fluid samples, reducing cross-contamination.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2022)
Article
Medicine, General & Internal
Joowon Chung, Dong Jun Oh, Junseok Park, Su Hwan Kim, Yun Jeong Lim
Summary: In this study, a deep learning algorithm was developed to classify gastrointestinal organs in capsule endoscopy videos. A novel method for visualizing the transitional area of each organ was proposed. The model achieved high accuracy and could be effectively used in clinical practice.
Article
Robotics
Yunjiang Wang, Tianjian Liu, Xinben Hu, Keji Yang, Yongjian Zhu, Haoran Jin
Summary: Robot-assisted ultrasound scanning can reconstruct the volume with more intuitive images for examination and surgery guidance. A compliant joint based robotic ultrasound system (CJRUS) is proposed to provide safety and adaptive capacity for scanning the human spine.
IEEE ROBOTICS AND AUTOMATION LETTERS
(2023)
Review
Gastroenterology & Hepatology
Priya Oka, Mark McAlindon, Reena Sidhu
Summary: Capsule endoscopy is a non-invasive and well-tolerated method for examining the entire gastrointestinal tract. It has the potential to provide a comprehensive examination of the small bowel. In routine clinical practice, the diagnostic sensitivity of colon capsule is comparable to colonoscopy.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2022)
Article
Acoustics
Haochen Kang, Xuejun Qian, Ruimin Chen, Robert Wodnicki, Yizhe Sun, Runze Li, Yan Li, K. Kirk Shung, Zhongping Chen, Qifa Zhou
Summary: A new method called 2-D ultrasonic array-based OCE imaging was proposed in this study, which combines the advantages of 3-D dynamic electronic steering of the 2-D ultrasonic array and high-resolution OCT. The system was validated and calibrated using a homogeneous phantom and tested on ex vivo rabbit corneal tissue, showing accurate mapping capabilities for tissue biomechanical properties and potential as a diagnostic tool in ophthalmology.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2021)
Article
Engineering, Electrical & Electronic
Yao Lu, Daquan Yu, Lixi Wan, Xiaodong Zhang, Min Xiang, Zhiqiang Zhang, Min Su, Weibao Qiu
Summary: A novel redistribution layer-first embedded fan-out wafer-level packaging process is proposed for 2-D ultrasonic transducer arrays, allowing signals to be fanned-out to a region larger than the array size. An anisotropic conductive film with low curing temperature is used for electrical and mechanical connection, ensuring that ultrasonic transducer arrays do not lose their piezoelectric property due to high curing temperatures. This process successfully fabricates thin film circuits with multilayer RDLs, offering a promising solution to the individual electrical connection challenge in the arrays.
IEEE ELECTRON DEVICE LETTERS
(2021)
Article
Acoustics
Suzi Liang, Zhiqiang Zhang, Xingying Wang, Min Su, Weibao Qiu, Hairong Zheng
Summary: The study developed a 40-MHz ultrahigh-frequency focused ultrasound transducer for picoliter precision liquid transfer, with a droplet ejection accuracy ranging from 28 to 439 pL. The effects of acoustic parameters on droplet size were studied, showing that a wide range of droplet sizes could be obtained by adjusting these parameters. This flexible picoliter liquid transfer based on a wide bandwidth, high-frequency ultrasound transducer makes automation easier and has broad prospects in biological research and industrial applications.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2021)
Article
Physics, Applied
Min Su, Xiangxiang Xia, Baoqiang Liu, Zhiqiang Zhang, Rong Liu, Feiyan Cai, Weibao Qiu, Lei Sun
Summary: A high frequency transducer with a Fresnel zone plate (FZP) for intravascular ultrasound imaging is proposed and optimized in this study, showing superior lateral imaging resolution in experiments.
APPLIED PHYSICS LETTERS
(2021)
Article
Engineering, Biomedical
Zhiqiang Zhang, Rong Liu, Guofeng Li, Min Su, Fei Li, Hairong Zheng, Weibao Qiu
Summary: The dual-mode ultrasound array offers a new and reliable strategy for image-guided ultrasound therapy applications, with advantages of real-time use, low cost, portability, and inherent registration between imaging and therapeutic coordinate systems. This technology enables three-dimensional ultrasound imaging and focus control, demonstrating its multifunctional capability in ultrasound imaging and therapeutic applications for small animal brains. The dual-mode 2D matrix array shows promising results for practical use in ultrasound image-guided non-invasive therapy applications.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Acoustics
Suzi Liang, Min Su, Baoqiang Liu, Rong Liu, Hairong Zheng, Weibao Qiu, Zhiqiang Zhang
Summary: This study evaluated the influence of blood on HD-IVUS imaging and found that blood significantly affects the imaging quality, with a 71.7% decrease in signal-to-noise ratio. Additionally, the study identified dextran 5% as a suitable flushing agent for HD-IVUS due to its minimal signal attenuation.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Article
Acoustics
Yizhe Sun, Laiming Jiang, Ruimin Chen, Runze Li, Haochen Kang, Yushun Zeng, Yongke Yan, Shashank Priya, Qifa Zhou
Summary: This study successfully developed a highly textured piezoelectric ceramic material and fabricated a 15 MHz ultrasound transducer based on this material. The experimental results showed that the fabricated transducer performed well in terms of image quality and has the potential for application in biomedical imaging.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Review
Acoustics
Danyang Ren, Chiye Li, Junhui Shi, Ruimin Chen
Summary: Photoacoustic imaging is a new hybrid biomedical imaging modality that combines the benefits of optical and ultrasound imaging. The advancement in high-frequency ultrasound transducer technology has greatly influenced the applications of photoacoustic imaging.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Article
Chemistry, Analytical
Chong Li, Ruimin Chen, Da Gao
Summary: This study presents two types of ultrasonic vibrators and comparatively analyzes their dust removal properties for microscopic particles. The experimental results indicate that the dust removal performance of the traveling wave oscillator is better than that of the standing wave oscillator. The two operating modes of the traveling wave vibrator produce orthogonal vibration displacements, which help improve the dust removal characteristics of the vibrators.
Review
Chemistry, Analytical
Danyang Ren, Yonggang Yin, Chiye Li, Ruimin Chen, Junhui Shi
Summary: Ultrasonic transducers have been widely used in ultrasonic and photoacoustic imaging systems, converting acoustic and electrical signals. Effort has been made to transform rigid transducers to become flexible and wearable, enabling self-alignment to complex surfaces and high quality detection performance. The review summarizes recent advances in flexible transducers, including material optimization, designs, and practical applications, and discusses potential challenges and future directions.
Article
Engineering, Biomedical
Baoqiang Liu, Min Su, Zhiqiang Zhang, Rong Liu, Lei Sun, Hairong Zheng, Weibao Qiu
Summary: A dual-element imaging catheter is proposed to overcome non-uniform rotational distortion (NURD) in intravascular ultrasound (IVUS) imaging. By replacing abnormal images with normal ones, obtained from a back-to-back arrangement of two similar elements, the NURD is eliminated and the imaging frame rate is doubled. The strategy shows promising results in clinical studies.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2023)
Article
Computer Science, Interdisciplinary Applications
Ruofan Wang, Jing Zhu, Yuqian Meng, Xuanhao Wang, Ruimin Chen, Kaiyue Wang, Chiye Li, Junhui Shi
Summary: This study proposes an adaptive machine learning method to predict and complement photoacoustic sensor channel data, improving image reconstruction in PACT imaging. The method achieved superior performance in simulation, phantom experiments, and in vivo experiments.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2023)
Article
Acoustics
Yu Qiang, Xingying Wang, Rong Liu, Xuan Han, Hairong Zheng, Weibao Qiu, Zhiqiang Zhang
Summary: In this work, a high-contrast sub-aperture volumetric imaging strategy is proposed to improve the imaging quality of a dual-mode matrix array. The experimental results show that the proposed sub-aperture imaging method can achieve comparable resolution to full aperture imaging, and improve the intensity of noise signal and the signal-to-noise ratio of tissue images.
Article
Computer Science, Information Systems
Bartas Abaravicius, Sandy Cochran, Srinjoy Mitra
Summary: A hybrid charge pump design with zero-reversion loss cross-coupled stage and a new self-biased serial-parallel design has been developed, showing a 60% area reduction compared to traditional Schottky diode-based Dickson charge pump. Post-layout simulations demonstrated a peak efficiency of 38% and achieving the maximum specified output voltage.
Article
Engineering, Biomedical
Gengxi Lu, Runze Li, Xuejun Qian, Ruimin Chen, Laiming Jiang, Zeyu Chen, K. Kirk Shung, Mark S. Humayun, Qifa Zhou
Summary: The study proposed a multi-layer model for layer-specific viscoelasticity estimation of biological tissues, and demonstrated its potential to significantly improve accuracy and expand clinical applications of shear wave elastography through experimental validation.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
