Review
Chemistry, Analytical
Ji Zheng, Xiaoxing Fang, Liping Li, Ruiping Zhang, Chao Li
Summary: This review focuses on the design, fabrication, and use of fluorescent nanoprobes for detecting biomolecules in living cells. The main elements of nanoprobes, such as nanocarriers, recognition elements, and signal transduction strategies, are briefly described. The advantages and disadvantages of representative biomolecule-responsive nanoprobes in practical applications are also analyzed. This review aims to stimulate discussion on the construction of next-generation nanoprobes for intelligent and precise detection in living cells, as well as the opportunities and challenges of translating these tools into clinical use.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Polymer Science
Nour M. AlSawaftah, Nahid S. Awad, William G. Pitt, Ghaleb A. Husseini
Summary: Stimuli-responsive nanoparticles have shown promising potential in overcoming the limitations of conventional chemotherapy. pH-sensitive nanoparticles, in particular, have proven to be highly efficient in delivering drugs to tumors compared to conventional nanoparticles. This review summarizes the different strategies used to develop pH-sensitive nanoparticles for cancer therapy.
Article
Chemistry, Multidisciplinary
Ruidong Cheng, Mingwei Xu, Xuehui Zhang, Jinqiang Jiang, Qiuyu Zhang, Yue Zhao
Summary: Poly(acrylic acid-co-N-vinylcaprolactam) (PAN) hydrogels with multiple hydrogen bonds exhibit pH-induced reversible dynamic behaviors. Transparent hydrogels placed in acid or DI water undergo a transition from transparency to opacity due to the formation of hydrogen bonds or protonation/deprotonation of COOH groups, respectively. This two-way dynamic transparency evolution in PAN-based hydrogel material enables a dynamic memory system for information memorizing-forgetting and recalling-forgetting.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Luzhi Liu, Qingqing Zhou, Qin He, Wengui Duan, Yan Huang
Summary: This study successfully constructed supramolecular vesicles with pH-triggering effect for drug delivery, which are formed by the complexation between a cationic pillar[5]arene and sodium dodecyl sulfonate. These vesicles efficiently loaded anticancer drug doxorubicin under neutral conditions and could control drug release in the simulated weak acid environment of tumor cells, showing promising potential for various biomedical applications.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Pierre Picchetti, Stefano Volpi, Marianna Rossetti, Michael D. Dore, Tuan Trinh, Frank Biedermann, Martina Neri, Alessandro Bertucci, Alessandro Porchetta, Roberto Corradini, Hanadi Sleiman, Luisa De Cola
Summary: The development of smart nanoparticles with responsive features has expanded the applications of NP-based drugs, vaccines, and diagnostic tools. By combining nucleic acid interactions and sol-gel chemistry, researchers have successfully incorporated synthetic nucleic acids into organosilica nanoparticles, enabling them to respond to various biological, physical, and chemical inputs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Polymer Science
Rachel Yie Hang Tan, Choy Sin Lee, Mallikarjuna Rao Pichika, Sit Foon Cheng, Ki Yan Lam
Summary: This review summarizes the applications of pH-responsive polyurethane in the biomedical and drug delivery fields in recent years, including controlled drug delivery systems for oral administration, intravaginal administration, and targeted drug delivery systems for chemotherapy treatment. Additionally, it discusses other applications such as surface biomaterials, sensors, and optical imaging probes.
Article
Engineering, Environmental
Yifan Wang, Zhengjie Peng, Youqing Yang, Zhonnan Li, Yujiao Wen, Meng Liu, Shikai Li, Lezhu Su, Zhi Zhou, Yongfa Zhu, Nan Zhou
Summary: By modifying the structure of gamma-FeOOH nanoarrays, the accurate controlled release of agrochemicals can be achieved, addressing the issue of environmental pollution caused by agrochemical abuse.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Polymer Science
Hsi-Chin Wu, Wei-Ting Kuo
Summary: The study developed a smart tumor-targeting co-delivery system capable of simultaneously delivering chemotherapy drugs and siRNA, with dual responsiveness and high cellular uptake efficiency. This system shows potential for application in functional co-delivery and tumor therapy.
Article
Chemistry, Physical
Chaolei Hu, Yimeng Sun, Gil van Wissen, Yitong Peng, Andrij Pich
Summary: In this study, visible light- and temperature-responsive poly(N-vinylcaprolactam) microgels decorated by donor-acceptor Stenhouse adducts (DASAs) were synthesized for the first time using a robust and straightforward post-modification synthesis route. The microgels exhibited homogeneous distributions and temperature responsiveness in aqueous solutions. The photoswitching behaviors of the microgels in different solvents were systematically investigated, and their size in aqueous solutions could be modulated by visible light irradiation. Moreover, the microgels showed potential application in the photostimulated delivery of hydrophobic drugs.
CHEMISTRY OF MATERIALS
(2022)
Article
Engineering, Chemical
Dan-Na Hu, Xiao-Jie Ju, Xing-Qun Pu, Rui Xie, Wei Wang, Zhuang Liu, Liang-Yin Chu
Summary: The copolymer Alg-g-PNA shows temperature and glucose responsiveness, with the ability to transition between sol and gel states for insulin delivery based on environmental conditions. Additionally, the hydrogels demonstrate good biocompatibility and reversible sol-gel transitions in response to changes in blood glucose levels, making them a promising option for self-regulating insulin delivery in diabetes therapy.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Review
Chemistry, Multidisciplinary
Jing-Xin Liu, Kai Chen, Carl Redshaw
Summary: Since the successful separation of different cucurbit[n]uril homologues in 2001, the field of cucurbit[n]uril supramolecular chemistry has rapidly developed. The combination of Q[n] cavity size and various external stimuli has led to the creation of various Q[n]-based mechanically interlocked molecules (MIMs), including (pseudo)rotaxanes, catenanes, dendrimers, and poly(pseudo)rotaxanes. This review article highlights the important advancements in the field of Q[n]-based MIMs over the past two decades, discusses examples of heterowheel (pseudo)rotaxanes and poly(pseudo)rotaxanes involving Q[n]s, and reflects on the opportunities and challenges of constructing Q[n]-based stimuli-responsive MIMs.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Biochemistry & Molecular Biology
Yandong Ma, Zhihua Zhang, Fan Sun, Pierre Mesdom, Xin Ji, Pierre Burckel, Gilles Gasser, Min-Hui Li
Summary: Polymer micelles/vesicles made of a red-light-responsive block copolymer are developed as a model system for anticancer phototherapy. The system can release Ru complexes and generate ROS under red-light irradiation, leading to high cytotoxicity against cancer cells.
Article
Polymer Science
Zahn Stanvliet, Yiyi Deng, Dietmar Appelhans, Silvia Moreno, Susanne Boye, Jens Gaitzsch, Albena Lederer
Summary: This study investigates the temperature sensitivity of polymeric nanoparticles based on tertiary amine methacrylate block copolymers. The research shows that these nanoparticles can undergo a reversible morphological transformation in response to changes in pH and temperature. The findings also demonstrate the ability to lock their intermediate self-assembly structures through cross-linking and validate the morphology transition using analytical tools, which opens up new possibilities for responsive nanocarriers.
Article
Polymer Science
Yiluo Hu, Yohan Kim, Inki Hong, Moosung Kim, Seunho Jung
Summary: Agarose/succinoglycan hydrogels exhibit significantly improved flexibility, stability, and swelling pattern compared to agarose gels alone, and they also demonstrate pH-responsive drug delivery of ciprofloxacin. The non-toxicity of these hydrogels makes them potential natural biomaterials for biomedical applications.
Article
Chemistry, Physical
Feng-Qin Luo, Guojun Chen, Wei Xu, Daojia Zhou, Jia-Xian Li, Yong-Cong Huang, Run Lin, Zhen Gu, Jin-Zhi Du
Summary: The study presents a novel glucose-responsive insulin delivery system using pH-sensitive insulin-loaded nanoparticles and glucose oxidase-catalase-loaded pH-insensitive nanoparticles. This system effectively regulates blood glucose levels within normal ranges for a prolonged period and reduces inflammation risks towards normal skin.
Article
Engineering, Electrical & Electronic
Xiangen Zhao, Juhyeong Lee, Gang Liu, Lei Jia, Yang Liu, Junjia He, Yaping Du
Summary: Multiple corona bursts occur in long positive sparks before leader inception, and they happen in different locations. The time sequence of the electrodes influences the discharge in the first five corona bursts. The first corona current is a single pulse, while the following corona currents are mostly a superposition of multiple pulses. These findings are significant for optimizing long spark experiments.
Article
Chemistry, Multidisciplinary
Xiaomeng Shi, Zhichao Zeng, Hongtu Zhang, Yunhui Huang, Chun-Hua Yan, Yaping Du
Summary: Rare earth-based halide solid electrolytes (RE-HSEs) are promising due to their comprehensive properties. A highly purified RE-HSE Li3ErBr6 (LErB) with high ionic conductivity and electrochemical window is successfully synthesized. The LErB is used in a solid Li-SeS2 battery, showing stable cycling performance and good rate performance. The assembled pouch-type cell with LErB can light a diode array after bending and cutting, proving the practicality of LErB-based Li-SeS2 cells in battery packaging and operation.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Mathematics
Yaping Du, Jian-Wen Sun
Summary: This paper focuses on a class of nonlocal dispersal problem with Dirichlet boundary conditions. The limit of solutions is analyzed when the dispersal kernel is rescaled. The main results show that the solutions of the Dirichlet heat equation can be approximated by the nonlocal dispersal equation. The investigation also reveals that the nonlocal dispersal equation is similar to the convection-diffusion equation by using another special kernel function.
BULLETIN OF THE MALAYSIAN MATHEMATICAL SCIENCES SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Xiaoyun Chen, Xiaomeng Shi, Mingren Cheng, Mengzhen Zhang, Jiamin Ma, Zhong Liang, Xinyun Zhai, Yaping Du
Summary: Recently, there has been extensive research on metal organic framework (MOF) derived electrode materials. The porous structure of MOFs provides a large contact area on the electrode/electrolyte interface, which enhances mass transfer and volume buffering during cycling. In this study, a polyhedron morphology Fe3O4@N-doped carbon hybrid material (Fe3O4@NC) was synthesized by coating MIL-53(Fe) with polydopamine (PDA). The porous encapsulation structure with well-connected carbon networks improves ion intercalation and the stability of the solid electrolyte interface (SEI) layer. Porous Fe3O4@NC nanorods exhibited a specific capacity of 750 mA h g(-1) after 700 cycles at a high current density of 0.5 A g(-1) and high-rate capability of 272 mA h g(-1) at 5 A g(-1). The synthesis of FeS2@NC demonstrates the possibility of modifying electrode materials. This work provides a design scheme to enhance the electrochemical performances of MOF-derived electrode materials and offers a general strategy for synthesizing other energy storage and conversion materials.
Article
Geosciences, Multidisciplinary
Xiangen Zhao, Nikolay A. A. Popov, Quan Gan, Yuxuan Ding, Yaping Du, Junjia He
Summary: The mechanism of space stem formation under lightning impulse voltage in a 1.35 m air gap was studied using high-speed direct imaging and Schlieren photography. The average length and diameter of the space stem were found to be approximately 5 mm and 0.5 mm, which are about 1/3 and 1/10 of the length and diameter of the local luminous region, respectively. Furthermore, the space stem exhibited a non-uniform distributed temperature with a maximum value of several hundred Kelvin for tens of microseconds. Thus, a possible mechanism was proposed involving the propagation of a secondary ionization wave from the HV electrode at the primary corona streamer boundary, which was sustained by fast gas heating and production of atomic oxygen.
GEOPHYSICAL RESEARCH LETTERS
(2023)
Article
Engineering, Electrical & Electronic
Jinxin Cao, Amedeo Andreotti, Yaping Du, Nagananthini Ravichandran, Yuxuan Ding
Summary: This letter discusses the selection of a lateral distance in the assessment area to evaluate the flashover rate caused by indirect lightning. An inappropriate choice can lead to assessment errors or increased computational burden. Unfortunately, there is no systematic discussion on this issue in the literature. The influence of this lateral distance on the flashover rate evaluation is discussed, and the concept of utmost lateral distance is introduced. A general procedure is provided to determine this utmost lateral distance, which can relieve the computational burden while preserving assessment accuracy.
IEEE TRANSACTIONS ON ELECTROMAGNETIC COMPATIBILITY
(2023)
Article
Engineering, Electrical & Electronic
Zhe Li, Yuxuan Ding, Yaping Du, Jinxin Cao, Mingli Chen
Summary: This article presents an integrated model for analyzing the interaction between the lightning channel and tall structures on the ground. The model takes into account the nonlinear, nonuniform, and time evolution characteristics of the lightning channel, and uses a partial element equivalent circuit method to model the wire structure on the ground. Experimental data verification and simulation results show that the proposed model more accurately describes the characteristics of lightning surges compared to the simple current source model.
IEEE TRANSACTIONS ON ELECTROMAGNETIC COMPATIBILITY
(2023)
Article
Chemistry, Physical
Zhichao Zeng, Xiaomeng Shi, Mingzi Sun, Hongtu Zhang, Wei Luo, Yunhui Huang, Bolong Huang, Yaping Du, Chun-Hua Yan
Summary: Rare-earth halide solid electrolytes (HSEs) have become a promising research area for all-solid-state lithium batteries due to their favorable electrochemical and mechanical properties. However, only a few high-performance HSEs have been reported so far. In this study, a vacuum evaporation-assisted method was used to synthesize Li3TbBr6 (LTbB), a RE-HSE, with an impressive ionic conductivity of 1.7 mS center dot cm(-1), wide electrochemical window, and good formability. A solid Li-Te battery based on LTbB showed excellent cycling stability for up to 600 cycles, surpassing previous reports. Various in situ and ex situ characterizations were conducted to investigate the discharge/charge processes of Li-Te batteries. Theoretical calculations revealed that the direct [octahedral]-[octahedral] ([Oct]-[Oct]) pathway played a dominant role in Li ion migrations in the electrolyte, with efficient electron transfer at the Tb sites and unaffected Li 2s orbitals during migration, resulting in a low activation barrier. The successful fabrication and application of LTbB offer a competitive solution for solid electrolytes in all-solid-state lithium batteries and highlight the potential of RE-based HSEs in energy devices.
Article
Chemistry, Physical
Zhong Liang, Lianpeng Song, Mingzi Sun, Bolong Huang, Yaping Du
Summary: In this study, novel single-atom InCe/CN catalysts were successfully prepared on a nitrogen-doped carbon matrix. Both AC-HAADF-STEM images and EXAFS spectra confirmed the well-dispersed In and Ce atoms. The prepared InCe/CN catalysts exhibited high Faradaic efficiency (77%) and current density (j(HCOOH)) for HCOOH formation in CO2 reduction reaction. Theoretical calculations showed that the introduced Ce single atom sites not only promoted electron transfer, but also increased the selectivity towards HCOOH formation by optimizing the In-5p orbitals. This work extends the design of single-atom catalysts to main group and Ln metals, providing more potential applications.
Review
Chemistry, Multidisciplinary
Hao Fu, Yaping Du
Summary: This review summarizes a strategy to prepare ultrathin nanowires (UCNWs) using nanoclusters as templates, which has the potential to be a general synthesis method for UCNWs.
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
(2023)
Article
Automation & Control Systems
Jiahua Lyu, Hong Cai Chen, Yaping Du, Qingsha S. Cheng
Summary: This article proposes an efficient numerical calculation algorithm named LitzImp for fast impedance extraction of Litz wire coil (LWC). LitzImp provides different simplification schemes for different coil structures, reducing the resource consumption in the repeated calculation for the same structures and improving efficiency while maintaining high accuracy. Comparative verification with finite element method (FEM) and analytical method shows the advantages of LitzImp in terms of efficiency and accuracy.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Article
Chemistry, Multidisciplinary
Shuai Zhang, Leilei Yin, Qingqing Li, Siyuan Wang, Weihua Wang, Yaping Du
Summary: Intermetallic Ir2Sm nanoparticles were synthesized and demonstrated to be excellent electrocatalysts for acidic oxygen evolution reaction. These nanoparticles exhibited significantly improved mass activity and stability compared to pure Ir nanoparticles. The alloying of Sm with Ir atoms in the Ir2Sm nanoparticles modulated the electronic nature of Ir, leading to enhanced oxygen evolution reaction activity.
Article
Green & Sustainable Science & Technology
Shuai Zhang, Mingzi Sun, Leilei Yin, Siyuan Wang, Bolong Huang, Yaping Du, Chun-Hua Yan
Summary: A solid-phase synthesis strategy is developed for the preparation of Ir-Ln (Ln = La, Ce, Pr, Nd) alloy nanoparticles on carbon supports, which serve as superior acidic OER catalysts. Among them, Ir2Pr alloy catalyst exhibits a maximum mass activity of 2.10 A mg(Ir)(-1) at 300 mV overpotential and stability over 200 h at 10 mA cm(-2) in 0.5 m H2SO4, which is 9.5 and 20 times higher compared to pure Ir nanoparticles. Theoretical calculations confirm the correlation between the OER performances and the rare earth elements in the alloy.
ADVANCED ENERGY AND SUSTAINABILITY RESEARCH
(2023)
Article
Chemistry, Physical
Hongtu Zhang, Zhichao Zeng, Xiaomeng Shi, Chun-Hai Wang, Yaping Du
Summary: One key aspect of solid-state electrolytes (SSEs) research is the ionic conductivity. However, the current SSEs have relatively low ionic conductivity, which cannot meet the requirements of practical applications. In this study, scandium-based halide SSEs (Li3-xSc1-x(Zr/Hf)(x)Cl-6, x = 0 to 0.5) were constructed. The highest ionic conductivities (1.61 and 1.33 mS/cm) and the lowest activation energies (0.326 and 0.323 eV) were observed in Li2.6Sc0.6Zr0.4Cl6 (LSZC ~0.4) and Li2.6Sc0.6Hf0.4Cl6 (LSHC ~0.4), respectively. The crystal structures and Li chemical environments were analyzed, indicating weaker Li-Cl bond strengths that facilitate the transportation of Li+. The potential explanation for the increased ionic conductivity was determined based on the bond valence site energy theory.
Article
Chemistry, Multidisciplinary
Mengdie Jin, Zhichao Zeng, Hao Fu, Siyuan Wang, Zongyou Yin, Xinyun Zhai, Qian Zhang, Yaping Du
Summary: In this study, highly stable perovskite nanocrystals were developed by doping Eu2+ into CsPbBr3. The Eu2+-doped CsPbBr3 nanocrystals exhibit tunable green-to-cyan emissions, high photoluminescence quantum yield, and good resistance to adverse conditions. The thermal stability of CsPbBr3 nanocrystals after Eu2+ doping is greatly enhanced, and they also show emissions of Eu2+. A cyan light emitting diode based on Eu2+-doped CsPbBr3 nanocrystals was fabricated, which displays narrow exciton emission under different current densities. This work provides a new approach to advancing perovskite nanomaterials for practical applications.
Article
Chemistry, Multidisciplinary
Abu Talha Aqueel Ahmed, Sankar Sekar, Shubhangi S. Khadtare, Nurul Taufiqu Rochman, Bathula Chinna, Abu Saad Ansari
Summary: In this study, MnCo2S4 nanosheet catalyst was successfully synthesized and found to exhibit superior performance in hydrogen evolution. Compared to MnCo2S4, MnCo2S4 showed low overpotentials, moderate Tafel slope, and excellent sustainability. The outstanding performance can be attributed to the increased number of electrochemically active sites and enhanced electronic conductivity on the catalyst surface.
Article
Chemistry, Multidisciplinary
Victor V. Maltsev, Elena A. Volkova, Elizaveta V. Koporulina, Diana D. Mitina, Vladimir L. Kosorukov, Anna I. Jiliaeva, Daniil A. Naprasnikov, Konstantin N. Gorbachenya, Viktor E. Kisel
Summary: The phase relationships, crystal properties and luminescence kinetics of two complex systems were studied, including unit cell parameters, segregation coefficients of impurities, and lifetimes of energy levels.
Article
Chemistry, Multidisciplinary
Xiaoman Zhang, Wangwang Xu, W. J. Meng, Andrew C. Meng
Summary: This study successfully grew high-quality single crystal AlScN nanowires through ultra-high vacuum reactive sputtering technique and characterized their structure and properties. The nanowires exhibit significantly reduced mosaic spread and predominantly single ferroelectric domains, as well as a high piezoelectric constant.
Article
Chemistry, Multidisciplinary
Tom E. de Vries, Elias Vlieg, Rene de Gelder
Summary: Networks are important for describing relationships between people, roads between cities, reactions between chemicals, and other interactions. Bipartiteness, dividing the network into two groups, can facilitate the study of the network's structure. We have developed an algorithm that can find a near-optimal bipartisation within a reasonable time frame and used it to uncover the hidden structure of the CSD cocrystal network.
Article
Chemistry, Multidisciplinary
Chuchu Han, Jing Yang, Xin Zhang, Aisen Li, Jiang Peng
Summary: An elastic crystal based on a photo-reactive acylhydrazone derivative is reported, which exhibits reversible bending behavior under UV irradiation and heating. The crystal undergoes reversible E<->Z isomerization under light and heating conditions. The crystal demonstrates excellent elastic properties and the bending can be controlled to control the output direction of red light.
Article
Chemistry, Multidisciplinary
Lingfeng Zhang, Yu Wang, Yefeng Wang, Shuai Liu, Na Zhang, Mingmin Yang, Haixia Ma, Zhaoqi Guo
Summary: This study designs and synthesizes a series of high-energy salts compounds without heavy metal ions and azide groups. The molecular structures and stability of the compounds are confirmed through single-crystal X-ray diffraction and intermolecular interaction analysis. Furthermore, the thermal stability, energetic properties, and electrical initiation properties of the compounds are investigated, suggesting their potential as primary explosives.
