Article
Biology
Chenhao Yu, Joel Martin Sacris, Yan Gai, Chi Hou Lei
Summary: This study presents a realistic three-dimensional model that accurately captures the deformation and stress distribution of sitting on an air-cell-based cushion. It resolves several shortcomings in previous models and allows for optimization of cushion design and operating conditions.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Plant Sciences
Longzhe Quan, Keyong Chen, Tianbao Chen, Hailong Li, Wenchang Li, Tianyu Cheng, Fulin Xia, Zhaoxia Lou, Tianyu Geng, Deng Sun, Wei Jiang
Summary: Currently, mechanical and chemical damage is the main method of weed control. The use of chlorophyll fluorescence technology to monitor the physiological state of weeds is significant in understanding the damage mechanism of mechanical and chemical stresses. The study provides insights into the effects of mechanical and chemical stresses on weed CF parameters and can guide efficient weed control operations in the future.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Immunology
Yan Li, Zhiguo Wang, Ye Liu, Hui Zhang, Yan Huang, Pengyu Gao, Yingzhe Hu, Quanchen Xu
Summary: This study observed the effect of hyperocclusion on the remodeling of gingival tissues in mice, finding that it triggered a series of adaptive responses including apoptosis, proliferation, and changes in inflammatory factor levels. The expression of p65, proinflammatory factors, and beta-catenin peaked at specific time points under hyperocclusion conditions, indicating a dynamic process of remodeling in the gingival tissues.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Chemistry, Physical
Jingjing Xia, Jun Yu, Siwen Lu, Qiushi Huang, Chun Xie, Zhanshan Wang
Summary: In this study, the nature of chemical and mechanical material removal during CMP is theoretically investigated and a microscale material removal model is established to predict the silicon surface morphology and explain the evolution of surface roughness and the source of polishing scratches.
Article
Biophysics
Jonas F. Eichinger, Maximilian J. Grill, Iman Davoodi Kermani, Roland C. Aydin, Wolfgang A. Wall, Jay D. Humphrey, Christian J. Cyron
Summary: The study presents a novel computational framework based on the finite element method to simulate key mechanobiological mechanisms of mechanical homeostasis. The framework replicates many experimental observations on short time scales, providing a systematic tool for future research on mechanical homeostasis.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2021)
Review
Materials Science, Multidisciplinary
Bhavesh Patel, Alessio Gizzi, Javad Hashemi, Yousif Awakeem, Hans Gregersen, Ghassan Kassab
Summary: The gastrointestinal tract is a continuous channel in the body responsible for digestion and waste elimination. The mechanical behavior of GI tissues is crucial for proper GI function. This article provides a systematic review of biomechanical constitutive models for GI tissues and identifies the need for more advanced modeling techniques.
MATERIALS & DESIGN
(2022)
Article
Engineering, Multidisciplinary
Chi Zhang, Long Qian, Hongwei Zhao
Summary: Research on the mechanical properties of different regions of the porcine cerebral cortex revealed variations in viscosity, shear modulus, and sensitivity to indentation speed. These findings provide valuable information for the establishment of a finite element model of the brain and the placement of brain chips.
JOURNAL OF BIONIC ENGINEERING
(2021)
Article
Physics, Multidisciplinary
Junxiang Huang, James O. Cochran, Suzanne M. Fielding, M. Cristina Marchetti, Dapeng Bi
Summary: This study investigates the mechanical properties of confluent tissues under shear deformation using a computational model. The findings show that undeformed tissues acquire finite rigidity above a critical strain and exhibit shear-driven rigidity and nonlinear response.
PHYSICAL REVIEW LETTERS
(2022)
Article
Green & Sustainable Science & Technology
Guofeng Song, Xianzhi Song, Fuqiang Xu, Gensheng Li, Yu Shi, Jiayan Ji
Summary: This research aims to quantify the contributions of mechanical and chemical behaviors to reservoir feature variation during geothermal production, and a fully coupled THMC model is developed. The findings show that the mechanical effect plays a major role near the injection well and in a short term, while the chemical effect is dominated far from the injection well.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Thermodynamics
Xudong Liu, Shuxun Sang, Xiaozhi Zhou, Ziliang Wang
Summary: In this paper, a fully coupled AHTMC model is constructed and applied to study CO2 enhanced coalbed methane. The simulation results show that CO2 injection can significantly decrease CH4 adsorption capacity, increase production rate, but also affect CO2 storage and drainage pH. The injection rate of CO2 has a significant influence on CO2-ECBM.
Article
Chemistry, Physical
Qing Mu, Zhuji Jin, Xiaolong Han, Ying Yan, Zili Zhang, Ping Zhou
Summary: The study investigated the effects of slurry pH on the chemical and mechanical actions of YAG in chemical mechanical polishing process. The results demonstrated the removal mechanisms at different pH values, providing insights for optimizing the polishing process.
APPLIED SURFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Louis Combe, Melina Durande, Helene Delanoe-Ayari, Olivier Cochet-Escartin
Summary: Mechanical cues such as stresses and strains play important roles in biological processes. Segmentation of individual cells can provide information on their mechanical environment, but traditional methods are time consuming and prone to errors. In this paper, we propose a simple Convolutional Neural Network approach for cell shape measurement, and we optimize the architecture and complexity of the network to achieve better performance.
Article
Chemistry, Physical
Sen Yang, Yongjun Lu, Bingbing Liu, Qi Che, Fenghui Wang
Summary: A multilayer thermo-chemical-mechanical model was proposed to investigate the effects of defect diffusion, thermal expansion mismatch, and mechanical bending deformation on mixed ionic-electronic conducting (MIEC) membranes used in solid oxide fuel cells (SOFCs). The study found that high tensile stress relieved the overall structural curvature of the multilayer system. Constraining the oxygen partial pressure significantly reduced the overall stress of the multilayer structure. Lowering the sintering temperature and chemical expansion coefficient improved the reliability of planar SOFCs. The results provide theoretical support for designing stable planar solid fuel cells.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Biochemistry & Molecular Biology
Youn-Bok Lee, Emma L. Scotter, Do-Young Lee, Claire Troakes, Jacqueline Mitchell, Boris Rogelj, Jean-Marc Gallo, Christopher E. Shaw
Summary: This study investigates the role of cytoplasmic TDP-43 in stress granule formation and response to stress, with findings suggesting that TDP-43 relocalizes to the cytoplasm through different mechanisms under different stress conditions. Additionally, the study demonstrates that relocalization of TDP-43 induces PARP cleavage, leading to cellular toxicity, and reveals changes in other cytoplasmic structures during stress recovery.
HUMAN MOLECULAR GENETICS
(2022)
Article
Clinical Neurology
Fei Mao, John L. Robinson, Travis Unger, Marijan Posavi, Defne A. Amado, Lauren Elman, Murray Grossman, David A. Wolk, Edward B. Lee, Vivianna M. Van Deerlin, Silvia Porta, Virginia M. Y. Lee, John Q. Trojanowski, Alice S. Chen-Plotkin
Summary: The study revealed that genotypes at the TMEM106B locus and hexanucleotide repeat expansions in C9orf72 were associated with the severity and regional distribution of TDP-43 pathology in neurodegenerative diseases. While C9orf72 expansions were linked to greater TDP-43 pathology in ALS, the relationship between TMEM106B genotype and TDP-43 pathology remained consistent. Manipulating TMEM106B levels showed a causal role in modifying the development of TDP-43 proteinopathy.
ACTA NEUROPATHOLOGICA
(2021)
Article
Biology
Charles A. Elder, Jensen S. Smith, Mustafa Almosawi, Ethan Mills, Brett R. Janis, Jonathan A. Kopechek, Willem F. Wolkers, Michael A. Menze
Summary: By using a biomimetics approach and trehalose as a cryoprotective agent, red blood cells can be successfully preserved for long-term storage without the need for time-consuming washing steps.
