Article
Peripheral Vascular Disease
Muhammad B. Khan, Rebecca Scherzer, Cora E. Lewis, Rakesh Malhotra, Joachim H. Ix, Michael G. Shlipak, Orlando M. Gutierrez
Summary: This study examined the associations between urine biomarkers and incident hypertension in young adults, and found that higher levels of urine EGF were associated with a lower risk of developing hypertension and lower increases in blood pressure over a 10-year period.
Article
Peripheral Vascular Disease
Corey K. Bradley, Eunhee Choi, Marwah Abdalla, Hiroyuki Mizuno, Michael Lam, Maria Cepeda, Dona Sangapalaarachchi, Justin Liu, Paul Muntner, Kazuomi Kario, Anthony J. Viera, Joseph E. Schwartz, Daichi Shimbo
Summary: For most people, high home blood pressure can be identified or ruled out with a high degree of confidence within 3 days or less of monitoring.
Article
Peripheral Vascular Disease
Bonita Falkner, Samuel S. Gidding, Carissa M. Baker-Smith, Tammy M. Brady, Joseph T. Flynn, Leslie M. Malle, Andrew M. South, Andrew H. Tran, Elaine M. Urbina
Summary: The overall prevalence of hypertension in childhood is 2% to 5%, with primary hypertension being the leading type, especially in adolescence. Excess adiposity, suboptimal lifestyles, and other factors like environmental stress, low birth weight, and genetic factors contribute to primary hypertension in children. Hypertensive children are at high risk of developing hypertension in adulthood and experiencing target organ injuries. Ambulatory and home blood pressure monitoring can aid in diagnosis. Primordial prevention through healthier diet and increased physical activity, along with evidence-based treatment guidelines, is crucial in reducing the prevalence of primary hypertension. Further research and clinical trials are needed to enhance recognition, diagnosis, and treatment outcomes.
Article
Peripheral Vascular Disease
Tali Elfassy, Charles A. German, Paul Muntner, Eunhee Choi, Gabriel Contreras, Daichi Shimbo, Eugene Yang
Summary: This study found that the association between blood pressure and cardiovascular disease mortality is sex-specific, with women having a higher risk of cardiovascular disease mortality at lower levels of systolic blood pressure compared to men.
Article
Peripheral Vascular Disease
Keisuke Narita, Satoshi Hoshide, Kazuomi Kario
Summary: This study analyzed the association between home and ambulatory blood pressure monitoring and cardiovascular risk in hypertensive outpatients, and found that both home blood pressure and ambulatory blood pressure were independently associated with cardiovascular risk. Home blood pressure had a modest superiority to predict cardiovascular prognosis compared to ambulatory blood pressure.
Article
Peripheral Vascular Disease
Paolo Palatini, Lucio Mos, Francesca Saladini, Marcello Rattazzi
Summary: This study found that an exaggerated systolic blood pressure response to standing is associated with sympatho-adrenergic hyperreactivity and is an independent predictor of major adverse cardiovascular and renal events in young hypertensive subjects. Orthostatic blood pressure assessment provides prognostic information in addition to ambulatory blood pressure monitoring.
Article
Peripheral Vascular Disease
Ramachandran S. Vasan, Rebecca J. Song, Vanessa Xanthakis, Alexa Beiser, Charles DeCarli, Gary F. Mitchell, Sudha Seshadri
Summary: This study examined the prevalence, correlates, and prognosis of hypertension-mediated organ damage (HMOD) in a community-based study. The findings showed that the prevalence of HMOD varied across different blood pressure guidelines and that the presence of HMOD increased the risk of cardiovascular disease.
Article
Peripheral Vascular Disease
Eva Munoz Aguilera, Jean Suvan, Marco Orlandi, Queralt Miro Catalina, Jose Nart, Francesco D'Aiuto
Summary: Recent evidence suggests a close relationship between hypertension and periodontitis, with individuals suffering from periodontitis showing higher systolic and diastolic blood pressure compared to those without. The diagnosis of periodontitis is associated with higher systolic blood pressure independently from common cardiovascular risk factors. Promoting periodontal and systemic health strategies may help reduce the burden of hypertension and its complications.
Article
Peripheral Vascular Disease
Guoying Wang, Jessie P. Buckley, Tami R. Bartell, Xiumei Hong, Colleen Pearson, Xiaobin Wang
Summary: This study found that cord blood insulin concentration is associated with the occurrence of hypertension in childhood. Fetuses with higher blood insulin concentration are more likely to develop hypertension later in life. Elevated cord blood insulin concentration beyond the normal range may increase the risk of hypertension.
Article
Peripheral Vascular Disease
Han Ma, Fangchao Liu, Jianxin Li, Jichun Chen, Jie Cao, Shufeng Chen, Xiaoqing Liu, Xueli Yang, Keyong Huang, Chong Shen, Ling Yu, Yingxin Zhao, Xianping Wu, Liancheng Zhao, Ying Li, Dongsheng Hu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
Summary: Based on a study conducted in China, the association between socioeconomic status (SES) and hypertension remains uncertain. Individuals with lower SES are at a higher risk of developing hypertension compared to those with higher SES. Moreover, women are more susceptible to the adverse effects of lower SES on hypertension.
Article
Peripheral Vascular Disease
Christopher E. Clark, Fiona C. Warren, Kate Boddy, Sinead T. J. McDonagh, Sarah F. Moore, Maria Teresa Alzamora, Rafel Ramos Blanes, Shao-Yuan Chuang, Michael H. Criqui, Marie Dahl, Gunnar Engstrom, Raimund Erbel, Mark Espeland, Luigi Ferrucci, Maelenn Guerchet, Andrew Hattersley, Carlos Lahoz, Robyn L. McClelland, Mary M. McDermott, Jackie Price, Henri E. Stoffers, Ji-Guang Wang, Jan Westerink, James White, Lyne Cloutier, Rod S. Taylor, Angela C. Shore, Richard J. McManus, Victor Aboyans, John L. Campbell
Summary: The study found that using blood pressure readings from the higher arm instead of the lower arm can more accurately diagnose and manage hypertension. Models based on higher arm BP performed better in predicting cardiovascular events and resulted in a higher reclassification rate of participants.
Review
Peripheral Vascular Disease
Gonzalo Saco-Ledo, Pedro L. Valenzuela, Miguel Ramirez-Jimenez, Javier S. Morales, Adrian Castillo-Garcia, James A. Blumenthal, Luis M. Ruilope, Alejandro Lucia
Summary: Studies have shown that a single bout of acute aerobic exercise can effectively reduce 24-hour, daytime, and nighttime blood pressure in hypertensive patients, with similar effects in both medicated and non-medicated individuals. Aerobic exercise has the most significant impact on blood pressure, while resistance or combined (aerobic and resistance) exercise has no significant effects on blood pressure.
Article
Peripheral Vascular Disease
Chloe Douglas, Jennifer T. Roem, Joseph L. Flynn, Susan A. Furth, Bradley M. Warady, Susan Halbach
Summary: Using data from the CKiD Study, this study found that younger children with chronic kidney disease are more likely to have unrecognized and untreated hypertensive blood pressure, highlighting the need for efforts to improve blood pressure control in this population.
Article
Peripheral Vascular Disease
Eun Hui Bae, Sang Yeob Lim, Bongseong Kim, Tae Ryom Oh, Su Hyun Song, Sang Heon Suh, Hong Sang Choi, Eun Mi Yang, Chang Seong Kim, Seong Kwon Ma, Kyung-Do Han, Soo Wan Kim
Summary: This study found that higher blood pressure is associated with an increased risk of end-stage renal disease (ESRD) in patients with diabetes. The risk is particularly higher in younger individuals. Age, sex, use of antihypertensive medication, and history of chronic kidney disease have different effects on the risk of ESRD.
Article
Cardiac & Cardiovascular Systems
Shishir Rao, Milad Nazarzadeh, Dexter Canoy, Yikuan Li, Jing Huang, Mohammad Mamouei, Gholamreza Salimi-Khorshidi, Aletta E. Schutte, Bruce Neal, George Davey Smith, Kazem Rahimi
Summary: This study analyzed health data from 475,442 individuals in the UK aged 60-90 who had at least one prescription of paracetamol. It found that paracetamol formulations containing sodium bicarbonate were associated with increased blood pressure, cardiovascular diseases, and all-cause mortality. However, further analysis showed that this association was primarily due to confounding by indication related to dysphagia and related conditions. Therefore, this study concludes that short-term use of sodium bicarbonate paracetamol in routine clinical practice does not increase the risk of elevated blood pressure and cardiovascular events.
EUROPEAN HEART JOURNAL
(2023)
Article
Environmental Sciences
Cataia Ives, Huaqin Pan, Stephen W. Edwards, Mark Nelms, Hannah Covert, Maureen Y. Lichtveld, Emily W. Harville, Jeffrey K. Wickliffe, Wilco Zijlmans, Carol M. Hamilton
Summary: The use of standardized measurement protocols and data standards improves the quality and consistency of data collection in environmental health studies, facilitating the combination of information from multiple studies. Our analysis of clinical measures and exposure assays from NIH resources revealed a wide collection of environmental assessment data and a lesser prevalence of biological assessment data. NIH resources can aid in identifying common data for meta-analysis and support data sharing.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Editorial Material
Public, Environmental & Occupational Health
Emily W. Harville
Summary: A recent study found that the COVID-19 vaccine has no impact on fertility in men or women, while COVID-19 infection may temporarily reduce male fertility. These findings are reassuring for those seeking pregnancy and highlight the need to incorporate reproductive health into clinical trials and advance fertility research on a global scale.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Peripheral Vascular Disease
Tao Zhang, Bingbing Fan, Shengxu Li, Xuan Wang, Yawei Kong, Lydia Bazzano, Jiang He, Wei Chen, Yinkun Yan
Summary: This study found that the impact of childhood body mass index (BMI) on adult carotid intima-media thickness (cIMT) is partly mediated by multiple cardiovascular risk factors in later life. The deleterious effects of adiposity on vascular structure begin early in life and accumulate over time.
Article
Peripheral Vascular Disease
Bingbing Fan, Wei Lv, Jie Xu, Xiwa Hao, Aichun Cheng, Xia Meng, Wei Chen, Tao Zhang, Yongjun Wang
Summary: This study examines the associations between functional outcomes following acute ischemic stroke and ambulatory pulse rate (PR), finding that PR is associated with short-term neurologic disability and demonstrates distinct variations throughout a 24-hour cycle.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Environmental Sciences
Zhiqiang Che, Huixun Jia, Renjie Chen, Keyu Pan, Zhe Fan, Chang Su, Zhenyu Wu, Tao Zhang
Summary: This study found that exposure to a mixture of brominated flame retardants is positively associated with metabolic syndrome and its components in adults. PBB153, PBDE28, and PBDE209 were identified as significant chemicals in this association.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Cardiac & Cardiovascular Systems
Yinkun Yan, Xuan Wang, Shengxu Li, Dianjianyi Sun, Lijun Fan, Lydia Bazzano, Jiang He, Tao Zhang, Wei Chen
Summary: This study aims to investigate the temporal relationship between uric acid (UA) and insulin and their joint impact on type 2 diabetes mellitus (T2DM) in middle-aged adults. The results suggest that UA and insulin influence each other in non-diabetic individuals and play pathogenic roles in the development of T2DM.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Clinton Hall, Ava Marie S. Conlin, Monica Burrell, Celeste J. Romano, Anna T. Bukowinski, Gia R. Gumbs, Emily W. Harville, Dana L. Thomas, Hristina Denic-Roberts, Jennifer A. Rusiecki
Summary: This study evaluated the potential adverse health outcomes among infants born to US Coast Guard responders to the Deepwater Horizon oil spill disaster. The health outcomes of infants born to male responders were similar to non-responders, while infants born to female responders had a higher frequency of poor live birth outcomes. However, the findings should be interpreted with caution due to the small sample size.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Environmental Sciences
Josh Alarcon, Lauren Ward, Ke Pan, Elaina Gonsoroski, Christopher K. Uejio, Leslie Beitsch, Maureen Y. Lichtveld, Emily W. Harville, Samendra Sherchan
Summary: Increased occurrences of harmful algal blooms (HAB) in the Gulf of Mexico and worldwide have raised concerns about brevetoxin exposure leading to respiratory illness or death, highlighting the need for extensive scientific research and human health monitoring.
JOURNAL OF WATER AND HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Emily W. Harville, Moira E. Wood, Elizabeth F. Sutton
Summary: The effect of social distancing due to the COVID-19 pandemic on the mental health of pregnant women is of particular concern. The study found that greater social distancing was associated with more anxiety symptoms, but worse mental health, particularly anxiety, may also have contributed to greater social distancing behaviors.
Article
Oncology
Bingbing Gu, Shuai Zhang, Zhe Fan, Jiajing Che, Shuting Li, Yunfei Li, Keyu Pan, Jiali Lv, Cheng Wang, Tao Zhang, Jialin Wang
Summary: This study constructed a prognostic gene model for esophageal cancer (EC) by screening differentially expressed miRNAs (demiRNAs) and their target genes. Six genes (ARHGAP11A, H1.4, HMGB3, LRIG1, PRR11, and COL4A1) were identified as prognostic biomarkers for EC and showed significant clinical significance in EC prognosis.
TRANSLATIONAL CANCER RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Cheng Li, Yanzhi Li, Min Zhao, Cheng Zhang, Pascal Bovet, Bo Xi
Summary: According to the LE8, overall cardiovascular health (CVH) did not change among US adults from 2005 to 2018, as well as three components (diet, physical activity, and blood pressure). However, metrics such as nicotine exposure, blood lipids, and sleep health improved, while BMI and blood glucose deteriorated over time.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Public, Environmental & Occupational Health
Chuanwei Ma, Yayang Huang, Sixuan Li, Min Zhao, Xinying Zeng, Xinbo Di, Costan G. Magnussen, Bo Xi, Shiwei Liu
Summary: It is well-known that secondhand smoke exposure among adolescents in China is associated with increased morbidity and mortality. This study found that while prevalence of secondhand smoke exposure decreased from 2013-2014 to 2019, it still remains unacceptably high. More effective strategies and stronger action are needed in China to further reduce secondhand smoke exposure among adolescents.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Public, Environmental & Occupational Health
Ke Pan, Lydia A. Bazzano, Kalpana Betha, Brittany M. Charlton, Jorge E. Chavarro, Christina Cordero, Erica P. Gunderson, Catherine L. Haggerty, Jaime E. Hart, Anne Marie Jukic, Sylvia H. Ley, Gita D. Mishra, Sunni L. Mumford, Enrique F. Schisterman, Karen Schliep, Jeffrey G. Shaffer, Daniela Sotres-Alvarez, Joseph B. Stanford, Allen J. Wilcox, Lauren A. Wise, Edwina Yeung, Emily W. Harville
Summary: The PrePARED Consortium has created a valuable resource by merging data from multiple cohort studies to address preconception health. They have pooled individual-level data from 12 prospective studies and used a crosswalk-cataloging-harmonization procedure. The study provides opportunities to examine uncommon preconception risk factors and pregnancy-related events.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Jiahong Sun, Yanan Qiao, Min Zhao, Costan G. Magnussen, Bo Xi
Summary: This study provides a standardized and comprehensive estimation of the burden of cardiovascular diseases (CVDs) in youths and young adults, including prevalence, incidence, disability-adjusted life years (DALY), and mortality rate. The study found that while the overall burden of CVDs has decreased, the incidence and prevalence rates have increased. The burden of CVDs varies by age, sex, region, and country. The study highlights the importance of prevention and treatment of CVDs in young people.
Article
Oncology
Bingbing Gu, Shuai Zhang, Zhe Fan, Jiajing Che, Shuting Li, Yunfei Li, Keyu Pan, Jiali Lv, Cheng Wang, Tao Zhang, Jialin Wang
Summary: This study identified six genes as potential prognostic biomarkers for esophageal cancer and constructed a predictive model. The high-risk group showed shorter survival time and higher expression of M2 macrophages, while the expression of STAT3 checkpoints was attenuated compared to the low-risk group.
TRANSLATIONAL CANCER RESEARCH
(2023)
