Cumulus cells surrounding oocytes with high developmental competence exhibit down-regulation of phosphoinositol 1,3 kinase/protein kinase B (PI3K/AKT) signalling genes involved in proliferation and survival

Cited2 protein level in cumulus cells is a biomarker for human embryo quality and pregnancy outcome in one in vitro fertilization cycle

(2016) Yuan Fang et al.   FERTILITY AND STERILITY

Epigenetic alterations of CYP19A1 gene in Cumulus cells and its relevance to infertility in endometriosis

(2016) Elham Hosseini et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Segmented ART – The new era in ART?

(2016) Kemal Ozgur et al.   Reproductive Biology

Competence Classification of Cumulus and Granulosa Cell Transcriptome in Embryos Matched by Morphology and Female Age

(2016) Rehannah Borup et al.   PLoS One

Oxidative Stress Induces Mouse Follicular Granulosa Cells Apoptosis via JNK/FoxO1 Pathway

(2016) Qiannan Weng et al.   PLoS One

Use of Both Cumulus Cells’ Transcriptomic Markers and Zona Pellucida Birefringence to Select Developmentally Competent Oocytes in Human Assisted Reproductive Technologies

(2015) Mourad ASSIDI et al.   BMC GENOMICS

Assessing embryo quality by combining non-invasive markers: early time-lapse parameters reflect gene expression in associated cumulus cells

(2015) Elizabeth R. Hammond et al.   HUMAN REPRODUCTION

Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization

(2015) Giovanni Coticchio et al.   HUMAN REPRODUCTION UPDATE

Viability of cumulus cells is associated with basal AMH levels in assisted reproduction

(2014) Thomas Ebner et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update

(2014) Annu Makker et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Characterization of the human cumulus cell transcriptome during final follicular maturation and ovulation

(2014) G.M. Yerushalmi et al.   MOLECULAR HUMAN REPRODUCTION

Changes in granulosa cells gene expression associated with growth, plateau and atretic phases in medium bovine follicles

(2014) Gabriel Douville et al.   Journal of Ovarian Research

Comparison of gene expression profiles in granulosa and cumulus cells after ovulation induction with either human chorionic gonadotropin or a gonadotropin-releasing hormone agonist trigger

(2013) Tanni Borgbo et al.   FERTILITY AND STERILITY

Gene expression profiles of cumulus cells obtained from women treated with recombinant human luteinizing hormone + recombinant human follicle-stimulating hormone or highly purified human menopausal gonadotropin versus recombinant human follicle-stimulating hormone alone

(2013) Valentina Gatta et al.   FERTILITY AND STERILITY

Cumulus and granulosa cell markers of oocyte and embryo quality

(2013) Asli Uyar et al.   FERTILITY AND STERILITY

The transcriptome of follicular cells: biological insights and clinical implications for the treatment of infertility

(2013) Elpida Fragouli et al.   HUMAN REPRODUCTION UPDATE

New molecular markers for the evaluation of gamete quality

(2013) G. Ruvolo et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Wnt/β-catenin signaling regulates follicular development by modulating the expression of Foxo3a signaling components

(2013) Lei Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The study of mammalian oocyte competence by transcriptome analysis: progress and challenges

(2013) R. Labrecque et al.   MOLECULAR HUMAN REPRODUCTION

Expression of Cyclins and Cyclin-Dependent Kinase Inhibitors in Granulosa Cells from Bovine Ovary

(2013) T Shimizu et al.   REPRODUCTION IN DOMESTIC ANIMALS

Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo and in vitro oocyte maturation

(2012) Zamalou Gisèle Ouandaogo et al.   HUMAN REPRODUCTION

Incidence of apoptosis and transcript abundance in bovine follicular cells is associated with the quality of the enclosed oocyte

(2012) D. Janowski et al.   THERIOGENOLOGY

Transcriptome dynamics and molecular cross-talk between bovine oocyte and its companion cumulus cells

(2011) A Regassa et al.   BMC GENOMICS

Follicle environment and quality of in vitro matured oocytes

(2011) Marc-André Sirard   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Functional roles of the phosphatidylinositol 3-kinases (PI3Ks) signaling in the mammalian ovary

(2011) Wenjing Zheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Effects of reproductive aging and postovulatory aging on the maintenance of biological competence after oocyte vitrification: insights from the mouse model

(2011) Carla Tatone et al.   THERIOGENOLOGY

In Vitro Oocyte Maturation and Preantral Follicle Culture from the Luteal-Phase Baboon Ovary Produce Mature Oocytes

(2010) M. Xu et al.   BIOLOGY OF REPRODUCTION

Biomarkers of human oocyte developmental competence expressed in cumulus cells before ICSI: a preliminary study

(2010) Mourad Assidi et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Regulation of cell death in human fetal and adult ovaries—Role of Bok and Bcl-XL

(2010) Minna Jääskeläinen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome

(2010) Zhongwei Huang et al.   MOLECULAR HUMAN REPRODUCTION

Human cumulus cells as biomarkers for embryo and pregnancy outcomes

(2010) S. Assou et al.   MOLECULAR HUMAN REPRODUCTION

Subfertility Caused by Altered Follicular Development and Oocyte Growth in Female Mice Lacking PKBalpha/Akt11

(2009) Caitlin Brown et al.   BIOLOGY OF REPRODUCTION

Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration

(2009) Emad Afrasiabi et al.   CELLULAR SIGNALLING

Oocyte aging: cellular and molecular changes, developmental potential and reversal possibility

(2009) Y.-L. Miao et al.   HUMAN REPRODUCTION UPDATE

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

(2009) Lisette Stolk et al.   NATURE GENETICS

Akt expression in mouse oocytes matured in vivo and in vitro

(2009) Sandra Cecconi et al.   REPRODUCTIVE BIOMEDICINE ONLINE

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

Expression of forkhead transcription factors in human granulosa cells

(2008) Margareta D. Pisarska et al.   FERTILITY AND STERILITY

Assisted reproductive technologies in Canada: 2005 results from the Canadian Assisted Reproductive Technologies Register

(2008) Joanne Gunby et al.   FERTILITY AND STERILITY

Identification of differentially expressed markers in human follicular cells associated with competent oocytes

(2008) Melanie Hamel et al.   HUMAN REPRODUCTION