Sialic acid deficiency is associated with oxidative stress leading to muscle atrophy and weakness in GNE myopathy

Substantial deficiency of free sialic acid in muscles of patients with GNE myopathy and in a mouse model

(2017) Yiumo Michael Chan et al.   PLoS One

Sialyllactose ameliorates myopathic phenotypes in symptomatic GNE myopathy model mice

(2014) Takahiro Yonekawa et al.   BRAIN

Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

(2014) Ronald L. Schnaar et al.   PHYSIOLOGICAL REVIEWS

The Role of Metallothionein in Oxidative Stress

(2013) Branislav Ruttkay-Nedecky et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypothalamic S-Nitrosylation Contributes to the Counter-Regulatory Response Impairment following Recurrent Hypoglycemia

(2013) Xavier Fioramonti et al.   PLoS One

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Heterozygous UDP-GlcNAc 2-epimerase and N-acetylmannosamine kinase domain mutations in the GNE gene result in a less severe GNE myopathy phenotype compared to homozygous N-acetylmannosamine kinase domain mutations

(2012) Madoka Mori-Yoshimura et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Relationship between Human Aging Muscle and Oxidative System Pathway

(2012) Enrico Doria et al.   Oxidative Medicine and Cellular Longevity

Mechanistic Links Between Oxidative Stress and Disuse Muscle Atrophy

(2011) Scott K. Powers et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulfiredoxin Protein Is Critical for Redox Balance and Survival of Cells Exposed to Low Steady-state Levels of H2O2

(2011) Jin Young Baek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exacerbation of pathology by oxidative stress in respiratory and locomotor muscles with Duchenne muscular dystrophy

(2011) John M. Lawler   JOURNAL OF PHYSIOLOGY-LONDON

N-Acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis

(2011) Jessica R. Terrill et al.   NEUROMUSCULAR DISORDERS

Thiol Redox Transitions in Cell Signaling: a Lesson from N-Acetylcysteine

(2011) Tiziana Parasassi et al.   TheScientificWorldJOURNAL

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

(2010) Emilie Tresse et al.   Autophagy

Oxidative stress by monoamine oxidases is causally involved in myofiber damage in muscular dystrophy

(2010) Sara Menazza et al.   HUMAN MOLECULAR GENETICS

Prophylactic treatment with sialic acid metabolites precludes the development of the myopathic phenotype in the DMRV-hIBM mouse model

(2009) May Christine V Malicdan et al.   NATURE MEDICINE

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

Muscle weakness correlates with muscle atrophy and precedes the development of inclusion body or rimmed vacuoles in the mouse model of DMRV/hIBM

(2008) May Christine V. Malicdan et al.   PHYSIOLOGICAL GENOMICS