A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I
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Title
A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 26, Issue 16, Pages 3056-3068
Publisher
Oxford University Press (OUP)
Online
2017-05-20
DOI
10.1093/hmg/ddx190
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Note: Only part of the references are listed.- Inhibitors of histone deacetylase as antitumor agents: A critical review
- (2016) Mohammed Manal et al. BIOORGANIC CHEMISTRY
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- (2016) Fernande Freyermuth et al. Nature Communications
- Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy
- (2016) Guiying Chen et al. Scientific Reports
- Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy
- (2015) Suzanne G. Rzuczek et al. ACS Chemical Biology
- MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain
- (2015) Marianne Goodwin et al. Cell Reports
- Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor
- (2014) Chun-Ho Wong et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease
- (2014) Ranjan Batra et al. MOLECULAR CELL
- Myotonic Dystrophy
- (2014) Charles A. Thornton NEUROLOGIC CLINICS
- Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects
- (2014) Jason W. Hoskins et al. NUCLEIC ACIDS RESEARCH
- Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1
- (2014) Marzena Wojciechowska et al. RNA Biology
- The Mef2 Transcription Network Is Disrupted in Myotonic Dystrophy Heart Tissue, Dramatically Altering miRNA and mRNA Expression
- (2014) Auinash Kalsotra et al. Cell Reports
- Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts
- (2013) Matthew D. Disney DRUG DISCOVERY TODAY
- Compound loss of muscleblind-like function in myotonic dystrophy
- (2013) Kuang-Yung Lee et al. EMBO Molecular Medicine
- Myotonic dystrophy type 1 (DM1): A triplet repeat expansion disorder
- (2013) Ashok Kumar et al. GENE
- Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice
- (2013) Michael G. Poulos et al. HUMAN MOLECULAR GENETICS
- High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines
- (2013) Ami Ketley et al. HUMAN MOLECULAR GENETICS
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Design and Analysis of Effects of Triplet Repeat Oligonucleotides in Cell Models for Myotonic Dystrophy
- (2013) Anchel González-Barriga et al. Molecular Therapy-Nucleic Acids
- RNA-binding proteins in microsatellite expansion disorders: Mediators of RNA toxicity
- (2012) Gloria V. Echeverria et al. BRAIN RESEARCH
- Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
- (2012) Eric T. Wang et al. CELL
- Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise
- (2012) Christopher M. Chamberlain et al. HUMAN MOLECULAR GENETICS
- RNA Interference Targeting CUG Repeats in a Mouse Model of Myotonic Dystrophy
- (2012) Krzysztof Sobczak et al. MOLECULAR THERAPY
- Targeting nuclear RNA for in vivo correction of myotonic dystrophy
- (2012) Thurman M. Wheeler et al. NATURE
- Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
- (2012) Konstantinos Charizanis et al. NEURON
- RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1
- (2012) J. E. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of CaV1.1 calcium channel
- (2011) Zhen Zhi Tang et al. HUMAN MOLECULAR GENETICS
- Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy
- (2011) Frédérique Rau et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Bidirectional transcription stimulates expansion and contraction of expanded (CTG)•(CAG) repeats
- (2010) Masayuki Nakamori et al. HUMAN MOLECULAR GENETICS
- Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
- (2010) Hongqing Du et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing
- (2010) Emily S. Goers et al. NUCLEIC ACIDS RESEARCH
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ribonuclear inclusions and MBNL1 nuclear sequestration do not affect myoblast differentiation but alter gene splicing in myotonic dystrophy type 2
- (2009) Rosanna Cardani et al. NEUROMUSCULAR DISORDERS
- Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
- (2008) John C Castle et al. NATURE GENETICS
- A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
- (2008) A. Kalsotra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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