A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease

A splice site mutation inHERC1leads to syndromic intellectual disability with macrocephaly and facial dysmorphism: Further delineation of the phenotypic spectrum

(2016) Shagun Aggarwal et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Involvement of B-cell CLL/lymphoma 2 promoter methylation in cigarette smoke extract-induced emphysema

(2016) Huihui Zeng et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

(2016) András Kotschy et al.   NATURE

The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update

(2015) Waseem Ahmad Siddiqui et al.   ARCHIVES OF TOXICOLOGY

BiallelicHERC1mutations in a syndromic form of overgrowth and intellectual disability

(2015) O. Ortega-Recalde et al.   CLINICAL GENETICS

A nonsense variant in HERC1 is associated with intellectual disability, megalencephaly, thick corpus callosum and cerebellar atrophy

(2015) Lam Son Nguyen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Vascular complications in autosomal dominant polycystic kidney disease

(2015) Ronald D. Perrone et al.   Nature Reviews Nephrology

The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics

(2015) A. N. Hata et al.   Cancer Discovery

Immuno-miRs: critical regulators of T-cell development, function and ageing

(2014) Bart-Jan Kroesen et al.   IMMUNOLOGY

miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2

(2012) H. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes

(2012) Dan-Xia Zhu et al.   CARCINOGENESIS

Apoptotic Vascular Smooth Muscle Cell Depletion via BCL2 Family of Proteins in Human Ascending Aortic Aneurysm and Dissection

(2012) Serkan Durdu et al.   Cardiovascular Therapeutics

MicroRNA-181a – a tale of discrepancies

(2012) Aliaa M. Seoudi et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

DNA Methylation and Its Basic Function

(2012) Lisa D Moore et al.   NEUROPSYCHOPHARMACOLOGY

miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis

(2011) Haitao Bai et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease

(2011) Andrew W. Roberts et al.   JOURNAL OF CLINICAL ONCOLOGY

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes

(2011) Yi-Bing Ouyang et al.   MITOCHONDRION

Opposing effects of bim and bcl-2 on lung endothelial cell migration

(2010) Cathy Grutzmacher et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Post-transcriptional and post-translational regulation of Bcl2: Figure 1

(2010) Shaun Willimott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

(2010) L. Galluzzi et al.   CANCER RESEARCH

Bim is responsible for the inherent sensitivity of the developing retinal vasculature to hyperoxia

(2010) Shoujian Wang et al.   DEVELOPMENTAL BIOLOGY

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

Attenuation of retinal endothelial cell migration and capillary morphogenesis in the absence of bcl-2

(2008) Shuji Kondo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

Rescue of renal hypoplasia and cystic dysplasia in Bcl-2 −/− mice expressing Bcl-2 in ureteric bud derived epithelia

(2008) Shuji Kondo et al.   DEVELOPMENTAL DYNAMICS

Transforming Growth Factor-β Signaling in Thoracic Aortic Aneurysm Development: A Paradox in Pathogenesis

(2008) Jeffrey A. Jones et al.   JOURNAL OF VASCULAR RESEARCH

Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo

(2008) Feng Wei et al.   KIDNEY INTERNATIONAL