Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid

Clinical Use of Glutamine Supplementation

(2018) Jan Wernerman   JOURNAL OF NUTRITION

Pyrazinamide-induced hepatotoxicity and gender differences in rats as revealed by a 1H NMR based metabolomics approach

(2017) He Zhao et al.   Toxicology Research

Chemical Shifts to Metabolic Pathways: Identifying Metabolic Pathways Directly from a Single 2D NMR Spectrum

(2015) Abhinav Dubey et al.   ANALYTICAL CHEMISTRY

Biochemical characterization of blood plasma of coronary artery disease patients by in vitro high-resolution proton NMR spectroscopy

(2015) Anu Malik et al.   JOURNAL OF BIOSCIENCES

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?

(2015) Paula Iruzubieta et al.   Biomed Research International

Evaluation of mechanism of hepatotoxicity of leflunomide using albino wistar rats

(2014) Lal Lodhi   African Journal of Pharmacy and Pharmacology

Metabolite characterisation in peritoneal dialysis effluent using high-resolution1H and1H-13C NMR spectroscopy

(2014) Anupam Guleria et al.   MAGNETIC RESONANCE IN CHEMISTRY

A Novel Mechanism Underlies the Hepatotoxicity of Pyrazinamide

(2013) Tung-Yuan Shih et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metabolic signatures of esophageal cancer: NMR-based metabolomics and UHPLC-based focused metabolomics of blood serum

(2013) Xiaoli Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Olfactory disturbance related to pyrazinamide

(2013) C.- C. Tsou et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties

(2012) Sudipta Saha et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gene expression profiling reveals potential key pathways involved in pyrazinamide-mediated hepatotoxicity in Wistar rats

(2012) Yun Zhang et al.   JOURNAL OF APPLIED TOXICOLOGY

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Creatine as an antioxidant

(2011) Piero Sestili et al.   AMINO ACIDS

Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling

(2011) A. D. Patterson et al.   CANCER RESEARCH

Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst

(2011) Jianguo Xia et al.   Nature Protocols

Effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome

(2010) Domenico Giordano et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Plasma metabolomic profile in nonalcoholic fatty liver disease

(2010) Satish C. Kalhan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Monitoring liver alterations during hepatic tumorigenesis by NMR profiling and pattern recognition

(2010) Debora Paris et al.   Metabolomics

Direct toxicity effects of sulfo-conjugated troglitazone on human hepatocytes

(2010) Sudipta Saha et al.   TOXICOLOGY LETTERS

Amino acids: metabolism, functions, and nutrition

(2009) Guoyao Wu   AMINO ACIDS

Protein Carbonylation

(2009) Yuichiro J. Suzuki et al.   ANTIOXIDANTS & REDOX SIGNALING

NMR metabolomics and drug discovery

(2009) Robert Powers   MAGNETIC RESONANCE IN CHEMISTRY

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

(2009) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Liver cirrhosis and diabetes: Risk factors, pathophysiology, clinical implications and management

(2009) Diego Garcia-Compean et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo

(2008) Robin P. da Silva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

Anti-tuberculosis medication side-effects constitute major factor for poor adherence to tuberculosis treatment

(2008) Niyi Awofeso   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity

(2008) Alma Tostmann et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Evaluation of Population Pharmacokinetics and Exposure-Response Relationship With Coadministration of Amlodipine Besylate and Olmesartan Medoxomil

(2008) Shashank Rohatagi et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Metabolic Changes in Flatfish Hepatic Tumours Revealed by NMR-Based Metabolomics and Metabolic Correlation Networks

(2008) Andrew D. Southam et al.   JOURNAL OF PROTEOME RESEARCH

Antituberculosis drug-induced hepatotoxicity: Concise up-to-date review

(2007) Alma Tostmann et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY