TRPM4 expression is associated with activated B cell subtype and poor survival in diffuse large B cell lymphoma

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

(2016) Luigi Leanza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Calcium role in human carcinogenesis: a comprehensive analysis and critical review of literature

(2016) Bernard Kadio et al.   CANCER AND METASTASIS REVIEWS

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I

(2016) Xavier Daumy et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia

(2016) David B. Kurland et al.   Journal of Neuroinflammation

HIF-1α expression and high microvessel density are characteristic features in serrated colorectal cancer

(2016) Anne Tuomisto et al.   VIRCHOWS ARCHIV

Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer

(2016) Maryrose Constantine et al.   Scientific Reports

The Ca2+-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy

(2015) Miklós Kecskés et al.   BASIC RESEARCH IN CARDIOLOGY

TRPM4 in cardiac electrical activity

(2015) Romain Guinamard et al.   CARDIOVASCULAR RESEARCH

Novel perspectives in cancer therapy: Targeting ion channels

(2015) Annarosa Arcangeli et al.   DRUG RESISTANCE UPDATES

Low HIP1R mRNA and protein expression are associated with worse survival in diffuse large B-cell lymphoma patients treated with R-CHOP

(2015) Kah Keng Wong et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Diffuse Large B-Cell Lymphoma Classification System That Associates Normal B-Cell Subset Phenotypes With Prognosis

(2015) Karen Dybkær et al.   JOURNAL OF CLINICAL ONCOLOGY

Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis

(2015) Tapas K. Makar et al.   Journal of Neuroinflammation

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas

(2015) P J Brown et al.   LEUKEMIA

Increases in reactive oxygen species enhance vascular endothelial cell migration through a mechanism dependent on the transient receptor potential melastatin 4 ion channel

(2015) Daniela Sarmiento et al.   MICROVASCULAR RESEARCH

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

TRPM4 protein expression in prostate cancer: a novel tissue biomarker associated with risk of biochemical recurrence following radical prostatectomy

(2015) Kasper Drimer Berg et al.   VIRCHOWS ARCHIV

Myeloid differentiation primary response gene 88-leukotriene B4 receptor 2 cascade mediates lipopolysaccharide-potentiated invasiveness of breast cancer cells

(2015) Geun-Soo Park et al.   Oncotarget

TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility

(2015) Mónica Cáceres et al.   PLoS One

Rituximab: modes of action, remaining dispute and future perspective

(2014) Abdulmunem Abulayha et al.   Future Oncology

Focal adhesion protein expression in human diffuse large B-cell lymphoma

(2014) Rosa Bosch et al.   HISTOPATHOLOGY

Toll-Like Receptor 4 Prompts Human Breast Cancer Cells Invasiveness via Lipopolysaccharide Stimulation and Is Overexpressed in Patients with Lymph Node Metastasis

(2014) Huan Yang et al.   PLoS One

Transient receptor potential (TRP) channels, promising potential diagnostic and therapeutic tools for cancer

(2014) Jianpeng Chen et al.   BioScience Trends

Myeloid Differentiation Factor 88 Promotes Growth and Metastasis of Human Hepatocellular Carcinoma

(2013) B. Liang et al.   CLINICAL CANCER RESEARCH

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients

(2013) K K Wong et al.   LEUKEMIA

TRPM4 inhibition promotes angiogenesis after ischemic stroke

(2013) Kok Poh Loh et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A Microarray Platform-Independent Classification Tool for Cell of Origin Class Allows Comparative Analysis of Gene Expression in Diffuse Large B-cell Lymphoma

(2013) Matthew A. Care et al.   PLoS One

Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma

(2012) Pablo Conesa-Zamora et al.   INTERNATIONAL JOURNAL OF CANCER

Immunohistochemical Double-Hit Score Is a Strong Predictor of Outcome in Patients With Diffuse Large B-Cell Lymphoma Treated With Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone

(2012) Tina Marie Green et al.   JOURNAL OF CLINICAL ONCOLOGY

The TRPM4 Channel Controls Monocyte and Macrophage, but Not Neutrophil, Function for Survival in Sepsis

(2012) N. Serafini et al.   JOURNAL OF IMMUNOLOGY

Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program Study

(2012) C Visco et al.   LEUKEMIA

Influx of extracellular calcium participates in rituximab-enhanced ionizing radiation-induced apoptosis in Raji cells

(2012) Min Fengling et al.   TOXICOLOGY LETTERS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Gene-expression profiling and not immunophenotypic algorithms predicts prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy

(2011) G. Gutierrez-Garcia et al.   BLOOD

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

(2011) I. Salaverria et al.   BLOOD

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

(2011) Alvaro Becerra et al.   CARDIOVASCULAR RESEARCH

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

CD40 stimulation sensitizes CLL cells to rituximab-induced cell death

(2011) M Jak et al.   LEUKEMIA

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Trpm4 Differentially Regulates Th1 and Th2 Function by Altering Calcium Signaling and NFAT Localization

(2010) K. S. Weber et al.   JOURNAL OF IMMUNOLOGY

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

(2010) R. Eric Davis et al.   NATURE

CD20 as a Target for Therapeutic Type I and II Monoclonal Antibodies

(2010) Stephen A. Beers et al.   SEMINARS IN HEMATOLOGY

Rituximab inhibits B-cell receptor signaling

(2009) S. Kheirallah et al.   BLOOD

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

A requirement for calcium in the caspase-independent killing of Burkitt lymphoma cell lines by Rituximab

(2008) Ian Daniels et al.   BRITISH JOURNAL OF HAEMATOLOGY

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

(2008) T Grand et al.   BRITISH JOURNAL OF PHARMACOLOGY

TRPM4 regulates migration of mast cells in mice

(2008) Takahiro Shimizu et al.   CELL CALCIUM

Induction of Cytosolic Calcium Flux by CD20 Is Dependent upon B Cell Antigen Receptor Signaling

(2008) Claire A. Walshe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis

(2008) Verena Brune et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells

(2008) Gaëtan Barbet et al.   NATURE IMMUNOLOGY

Stromal Gene Signatures in Large-B-Cell Lymphomas

(2008) G. Lenz et al.   NEW ENGLAND JOURNAL OF MEDICINE