Blinded histopathological characterisation of POLE exonuclease domain- mutant endometrial cancers: sheep in wolf's clothing

The genetic landscape of endometrial clear cell carcinomas

(2017) Deborah F DeLair et al.   JOURNAL OF PATHOLOGY

Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition

(2017) Florine A. Eggink et al.   OncoImmunology

P16INK4a protein expression in endocervical, endometrial and metastatic adenocarcinomas of extra-uterine origin: Diagnostic and clinical considerations

(2017) Maria Angela Caponio et al.   Cancer Biomarkers

Regression of Chemotherapy-Resistant Polymerase   (POLE) Ultra-Mutated and MSH6 Hyper-Mutated Endometrial Tumors with Nivolumab

(2016) A. D. Santin et al.   CLINICAL CANCER RESEARCH

Endometrial Carcinomas with POLE Exonuclease Domain Mutations Have a Favorable Prognosis

(2016) M. K. McConechy et al.   CLINICAL CANCER RESEARCH

Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts

(2016) Ellen Stelloo et al.   CLINICAL CANCER RESEARCH

Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer

(2016) Janice M. Mehnert et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular genetic heterogeneity in undifferentiated endometrial carcinomas

(2016) Juan M Rosa-Rosa et al.   MODERN PATHOLOGY

A clinically applicable molecular-based classification for endometrial cancers

(2015) A Talhouk et al.   BRITISH JOURNAL OF CANCER

POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

(2015) I. C. van Gool et al.   CLINICAL CANCER RESEARCH

Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials

(2015) Tjalling Bosse et al.   EUROPEAN JOURNAL OF CANCER

Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients

(2015) Stefania Bellone et al.   GYNECOLOGIC ONCOLOGY

Histopathological features of endometrial carcinomas associated withPOLEmutations: implications for decisions about adjuvant therapy

(2015) Salwa Bakhsh et al.   HISTOPATHOLOGY

Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative

(2015) Ellen Stelloo et al.   MODERN PATHOLOGY

Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

(2015) Brooke E. Howitt et al.   JAMA Oncology

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

(2014) Eve Shinbrot et al.   GENOME RESEARCH

POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium

(2014) Bo Meng et al.   GYNECOLOGIC ONCOLOGY

Prognostic Significance of POLE Proofreading Mutations in Endometrial Cancer

(2014) David N. Church et al.   JNCI-Journal of the National Cancer Institute

Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations

(2014) Yaser R Hussein et al.   MODERN PATHOLOGY

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

(2013) David N. Church et al.   HUMAN MOLECULAR GENETICS

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

(2013) S. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-grade, Low-stage Endometrioid Endometrial Adenocarcinoma

(2012) Charles M. Quick et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Endometrial Giant Cell Carcinoma: A Case Series and Review of the Spectrum of Endometrial Neoplasms Containing Giant Cells

(2010) Anna Marie Mulligan et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial

(2010) RA Nout et al.   LANCET

Revised FIGO staging for carcinoma of the endometrium

(2009) William Creasman   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Morules in endometrioid proliferations of the uterus and ovary consistently express the intestinal transcription factor CDX2

(2008) O Houghton et al.   HISTOPATHOLOGY

Histologic and immunohistochemical decision-making in endometrial adenocarcinoma

(2008) Lesley Lomo et al.   MODERN PATHOLOGY