Comprehensive characterization of RSPO fusions in colorectal traditional serrated adenomas

RNF43 Is an Early and Specific Mutated Gene in the Serrated Pathway, With Increased Frequency in Traditional Serrated Adenoma and Its Associated Malignancy

(2016) Jia-Huei Tsai et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

(2016) John Hilkens et al.   GUT

Frequent PTPRK-RSPO3 fusions and RNF43 mutations in colorectal traditional serrated adenoma

(2016) Shigeki Sekine et al.   JOURNAL OF PATHOLOGY

R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice

(2016) Eugene Kang et al.   PLoS One

Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia and adenocarcinoma of the duodenum

(2015) A Matsubara et al.   BRITISH JOURNAL OF CANCER

Serrated tubulovillous adenoma of the large intestine

(2015) Mark Bettington et al.   HISTOPATHOLOGY

Traditional serrated adenoma (TSA): morphological questions, queries and quandaries

(2015) Runjan Chetty   JOURNAL OF CLINICAL PATHOLOGY

Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function

(2015) Elaine E. Storm et al.   NATURE

Wnt addiction of genetically defined cancers reversed by PORCN inhibition

(2015) B Madan et al.   ONCOGENE

The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength

(2014) W. de Lau et al.   GENES & DEVELOPMENT

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

(2014) Marion Lapierre et al.   JOURNAL OF CLINICAL INVESTIGATION

A clinicopathological and molecular analysis of 200 traditional serrated adenomas

(2014) Mark L Bettington et al.   MODERN PATHOLOGY

RSPO fusion transcripts in colorectal cancer in Japanese population

(2014) Kazuya Shinmura et al.   MOLECULAR BIOLOGY REPORTS

RNF43 is frequently mutated in colorectal and endometrial cancers

(2014) Marios Giannakis et al.   NATURE GENETICS

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

(2012) Bon-Kyoung Koo et al.   NATURE

Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma

(2011) Shigeki Sekine et al.   CANCER SCIENCE