Journal
HETEROCYCLES
Volume 95, Issue 2, Pages 1121-1131Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-16-S(S)83
Keywords
Cycloaddition Reaction; Cyclic Peptide; Triyne; Amino Acid
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Funding
- ACT-C from JST (Japan)
- Waseda University Grant for Special Research Projects
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Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.
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