Trehalose activates autophagy and decreases proteasome inhibitor-induced endoplasmic reticulum stress and oxidative stress-mediated cytotoxicity in hepatocytes

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

(2016) Brian J. DeBosch et al.   Science Signaling

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

(2016) Brian J. DeBosch et al.   Science Signaling

Alleviation mechanisms against hepatocyte oxidative stress in patients with chronic hepatic disorders

(2015) Masaaki Hiura et al.   HEPATOLOGY RESEARCH

Trehalose Reverses Cell Malfunction in Fibroblasts from Normal and Huntington's Disease Patients Caused by Proteosome Inhibition

(2014) Maria Angeles Fernandez-Estevez et al.   PLoS One

Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation

(2013) Yuichi Honma et al.   EXPERIMENTAL CELL RESEARCH

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

The autophagosome: origins unknown, biogenesis complex

(2013) Christopher A. Lamb et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy and apoptosis dysfunction in neurodegenerative disorders

(2013) Saeid Ghavami et al.   PROGRESS IN NEUROBIOLOGY

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation

(2012) Raymond Kwan et al.   FASEB JOURNAL

Chronic inflammation, immune escape, and oncogenesis in the liver: A unique neighborhood for novel intersections

(2012) Jimmy K. Stauffer et al.   HEPATOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Mallory–Denk Bodies Are Associated With Outcomes and Histologic Features in Patients With Chronic Hepatitis C

(2011) Mina O. Rakoski et al.   Clinical Gastroenterology and Hepatology

Endpoints and clinical trial design for nonalcoholic steatohepatitis

(2011) Arun J. Sanyal et al.   HEPATOLOGY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Mutant superoxide dismutase 1 overexpression in NSC-34 cells: Effect of trehalose on aggregation, TDP-43 localization and levels of co-expressed glycoproteins

(2010) Catarina Gomes et al.   NEUROSCIENCE LETTERS

Autophagy induction by trehalose counter-acts cellular prion-infection

(2009) Yasmine Aguib et al.   Autophagy

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Autophagy modulates keratin-containing inclusion formation and apoptosis in cell culture in a context-dependent fashion

(2008) M. Harada et al.   EXPERIMENTAL CELL RESEARCH

Huntington’s disease: degradation of mutant huntingtin by autophagy

(2008) Sovan Sarkar et al.   FEBS Journal

Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation

(2008) Masaru Harada et al.   HEPATOLOGY

Experimental and Computational Studies Investigating Trehalose Protection of HepG2 Cells from Palmitate-Induced Toxicity

(2007) Sukit Leekumjorn et al.   BIOPHYSICAL JOURNAL